DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rca1 and Fbxo43

DIOPT Version :9

Sequence 1:	NP_477214.1	Gene:	Rca1 / 33959	FlyBaseID:	FBgn0017551	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_001012117.2	Gene:	Fbxo43 / 315034	RGDID:	1310225	Length:	664	Species:	Rattus norvegicus

Alignment Length:	401	Identity:	95/401 - (23%)
Similarity:	132/401 - (32%)	Gaps:	144/401 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 LLEDAEGENCRNASNTTTFFRGLNTPSGHQEQDLYWGKPYPRTQ--PQKKFSAEEEPFSMTPRLQ 108
            :||..:|...::...|.:|....|||:.....:|:......|.:  ..::||.|.|...:. |||
  Rat   371 VLESQQGSEEKSGDLTLSFKDLSNTPALQLVCELFMKSKRKRFEQADDQEFSEEREEGKIA-RLQ 434

  Fly   109 DEHSLPKRRKKHFQSPHSSPKKSKKLLFPHIEEPPKNRFYGGVEKLDIVAKLAQWQPALQCILRH 173
              |.|             :....||:               |:|:|||:.:| |::.     |:|
  Rat   435 --HVL-------------AGLIGKKM---------------GIERLDILTEL-QYRN-----LKH 463

  Fly   174 VGAHTLDVMT--------KVSPAWK--------------------------QAVYRSQRDLERLQ 204
            :.|..||.:|        .||..|:                          .||.|.|....||:
  Rat   464 ILAMVLDSLTAESLYSAWNVSRNWRGIVAQDKRANRRRKLFIAQLKAKAQGAAVLRVQDAATRLR 528

  Fly   205 -NHRLKLNLTKENPHVPKRCSHVPKANHTVPLQTSNHSSLANSAASLMDSGNSSIHLMDVDAGRV 268
             ..||.|...:.....|.      ..|...|.|:.....|...|:|      |..||..
  Rat   529 LLSRLALRSVQAQAQAPN------GQNEQAPAQSPWGEVLTPVASS------SLTHLRS------ 575

  Fly   269 LREQTQRVKCPRCGRGSRVFISEAAKCGENLLSQTLPIGRTTSTFPCMTGPPLKRFLSLDLDEVR 333
              :|.|.:|..|     .:|..||.|          |..|..|  |....|..||.|
  Rat   576 --KQEQYLKVAR-----TLFTDEALK----------PCPRCQS--PAKYQPHKKRGL-------- 613

  Fly   334 TSPQGPPYNFAECTSVICQFRFCVNCLCKSHPGERCLVTELDTPSKLMMPRERLTPPQRAQNRDP 398
                        |:.:.|.|.|||.|||..|..|.|    ....:|....|:.|  |..||:
  Rat   614 ------------CSRLACGFDFCVLCLCAYHGSEDC----RRGSAKGRGSRDVL--PGSAQS--- 657

  Fly   399 KITRKNSLKRL 409
                |.:||||
  Rat   658 ----KRNLKRL 664

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rca1	NP_477214.1	None
Fbxo43	NP_001012117.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..98
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	315..358
		IBR	579..633	CDD:279784	24/90 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	637..664		10/39 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353704
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28JDS
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_114765
Panther	1	1.100	-	-	O	PTHR15493
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.790