DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sens-2 and ZNF165

DIOPT Version :9

Sequence 1:	NP_001285692.1	Gene:	sens-2 / 33957	FlyBaseID:	FBgn0051632	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	NP_001363420.1	Gene:	ZNF165 / 7718	HGNCID:	12953	Length:	485	Species:	Homo sapiens

Alignment Length:	178	Identity:	68/178 - (38%)
Similarity:	97/178 - (54%)	Gaps:	18/178 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   501 HQFSDLYSCMKCEKMFSTPHGLEVHSRRTHHGKKPYACELCNKTFGHEVSLSQHRAVHNVEKVFE 565
            ||:.         |.|.:|. |..|: ....|.|.:.|..|.|.|.|...|::|:.:|..|:.:|
Human   320 HQYG---------KSFKSPK-LAKHA-AVFSGDKTHQCNECGKAFRHSSKLARHQRIHTGERCYE 373

  Fly   566 CKQCGKRFKRSSTLSTHLLIHSDTRPYPCNYCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFS 630
            |.:|||.|..||.|:.|..||:..||:.|..||:.|:..|.:.:|..|||.|||::|..|||.|.
Human   374 CNECGKSFAESSDLTRHRRIHTGERPFGCKECGRAFNLNSHLIRHQRIHTREKPYECSECGKTFR 438

  Fly   631 QSSNLITHSRKHTGYKPFSCKLCHKAFQRKVDLRRHKETQHTDLRVHL 678
            .||:||.|.|.|||.||:.|..|.:||.:..:|.:|:       |:|:
Human   439 VSSHLIRHFRIHTGEKPYECSECGRAFSQSSNLSQHQ-------RIHM 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sens-2	NP_001285692.1	COG5048	<504..672	CDD:227381	64/167 (38%)
		C2H2 Zn finger	509..530	CDD:275368	5/20 (25%)
		zf-H2C2_2	522..545	CDD:290200	7/22 (32%)
		C2H2 Zn finger	538..558	CDD:275368	7/19 (37%)
		zf-H2C2_2	550..575	CDD:290200	10/24 (42%)
		C2H2 Zn finger	566..586	CDD:275368	9/19 (47%)
		zf-H2C2_2	579..603	CDD:290200	10/23 (43%)
		C2H2 Zn finger	594..614	CDD:275368	6/19 (32%)
		zf-H2C2_2	606..631	CDD:290200	12/24 (50%)
		C2H2 Zn finger	622..642	CDD:275368	11/19 (58%)
		zf-H2C2_2	634..657	CDD:290200	11/22 (50%)
		C2H2 Zn finger	650..677	CDD:275368	7/26 (27%)
ZNF165	NP_001363420.1	SCAN	45..157	CDD:128708
		C2H2 Zn finger	297..314	CDD:275368
		zf-C2H2	344..366	CDD:333835	7/21 (33%)
		C2H2 Zn finger	346..366	CDD:275368	7/19 (37%)
		COG5048	370..>431	CDD:227381	26/60 (43%)
		zf-C2H2	372..394	CDD:333835	10/21 (48%)
		C2H2 Zn finger	374..394	CDD:275368	9/19 (47%)
		C2H2 Zn finger	402..422	CDD:275368	6/19 (32%)
		COG5048	426..>479	CDD:227381	25/59 (42%)
		C2H2 Zn finger	430..450	CDD:275368	11/19 (58%)
		C2H2 Zn finger	458..478	CDD:275368	7/26 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	158	1.000	Inparanoid score	I4275
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050