Protein Alignment sens-2 and LOC1280253

DIOPT Version :10

• Sequence 1: NP_723223.1
• Gene: sens-2 / 33957
• FlyBaseID: FBgn0051632
• Length: 746
• Species: Drosophila melanogaster
• Sequence 2: XP_061514316.1
• Gene: LOC1280253 / 1280253
• VectorBaseID: AGAMI1_005547
• Length: 752
• Species: Anopheles gambiae
• Alignment Length: 832
• Identity: 182/832 - (21%)
• Similarity: 280/832 - (33%)
• Gaps: 292/832 - (35%)

  Fly     6 MQATSGQHLLHPAAPPAHQHHLPLDYSLGNFKPAIASDFPGPFLTSQQSSSASNSASSSAAATVP 70
            :..:|.:.:..|.:||.    :||...    .|.:....|      ...|:|.|..|.....|.
Mosquito     7 LSLSSPRGMQEPCSPPG----IPLTAK----SPTMEGAVP------DAESAADNGPSPHGPVTT- 56

  Fly    71 LQVRDLSALTAMATIPSPTQLLHQ-----RIQMSADAALGHHQQQPAQNPNPNPNHPQPQMPPAS 130
                .::..|..|||..|...:.:     .::.|....:|...:...:.......|.:
Mosquito    57 ----TITTTTTTATISRPAAKIQRPSGGATLKFSIANIMGQEHEDDEEEDREEERHDR------- 110

  Fly   131 TSPHE----------------------------------YAPMSAFKAVLPKKRNSDDASLAFSI 161
              .||                                  .:|.|....:..::.:|.:.|::
Mosquito   111 --EHEEEDEEDELEDDVDEDDEDAVVDVASEDETIELSMVSPGSGSSMLRKRRHDSHEKSMS--- 170

  Fly   162 SRLVKTEQLTAMAAAVGLKPPT-----------------------PLEDNNNSISMLSK------ 197
                   .|:|..::...:|||                       |...:|....:||:
Mosquito   171 -------PLSAAGSSPCYEPPTTAASSVAEAYDSAFKKYVPNSMHPFVASNRHQELLSQYPLLYY 228

  Fly   198 -NQQM----------HQQHHQQSHLAQRPKPAFISASEKLRRQSRSRSRSRSRSPCSSQID---- 247
             .|.|          |||||||.|.......|.::|........|..|.:.|..|..:.:.
Mosquito   229 PGQLMCAAAQYAALTHQQHHQQQHHHHHHHAAAVAALHPYGAPGRLHSPTLSPPPTGASLQTTTV 293

  Fly   248 MEDADSNHSHRSLHSRSRSRSRSRSHSRSRSHSSSSSVELEVDSPPGSPRISSPSGASASASELL 312
            ::.|..:.:|.:::.|         |..:..|..               .:|:.:.|:|:|:...
Mosquito   294 VQSASVHGAHGAMNGR---------HLHAGGHHQ---------------LLSAAAAAAAAAAAAA 334

  Fly   313 ITANGGGRSIGSKKSDLFSVSALLRRDEPPPQRRTPRSPPLGHLTSSGLAMPFNPLEAMRQGYPP 377
            .||..||:: |||:::|                ....|.....|:|||.::
Mosquito   335 ATATSGGKT-GSKRANL----------------NHSTSSTCSSLSSSGSSV-------------- 368

  Fly   378 NYDAAMFQRPLFSPALPFFAAVAFHQGQQQQQQQQQQQSGLAAGYHPDSQENLFRLRSLMVPLQS 442
                                                  .|...|..||...|
Mosquito   369 --------------------------------------GGSPGGSGPDGSLN------------- 382

  Fly   443 AGQNNSSAAAAAAAAAAAAVGVGVGVGVGVPPNGGHLGLPHSPHLHHFHHMAAKWPGLHQFSDLY 507
               ::||::||||||||||                               ||||       ...:
Mosquito   383 ---SSSSSSAAAAAAAAAA-------------------------------MAAK-------QKTF 406

  Fly   508 SCMKCEKMFSTPHGLEVHSRRTHHGKKPYACELCNKTFGHEVSLSQHRAVHNVEKVFECKQCGKR 572
            :|.:|.|:|:..:.|..| ...|.|.:|:.|::|.|.|....:|.:|:.:|..||..:|:.|||.
Mosquito   407 ACPECGKVFNAHYNLTRH-MPVHTGARPFICKICGKGFRQASTLCRHKIIHTSEKPHKCQTCGKA 470

  Fly   573 FKRSSTLSTHLLIHSDTRPYPCNYCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLIT 637
            |.|||||:||..||:..:||.|.||||.||||.:.|.|...|:|:|.:||.:|.|||.|..||..
Mosquito   471 FNRSSTLNTHTRIHAGYKPYICEYCGKGFHQKGNYKNHKLTHSGDKAYKCTICNKAFHQIYNLTF 535

  Fly   638 HSRKHTGYKPFSCKLCHKAFQRKVDLRRHKE--------------------TQHTDLRVHLGKVD 682
            |...|...|||:||:|.|.|.|..||::|..                    .||.....|.|..
Mosquito   536 HMHTHNDKKPFTCKICAKGFCRNFDLKKHMRKLHDVSMGGGHKRSRSCGTPQQHHHHHHHRGSP- 599

  Fly   683 FMSAAAAAAASAELSAAAAAAAAAGGSVP-GGGPPGSQGANAVGSAPNGAPP 733
             ::|.:.....|.|.|..|....:..:.| ...||...|:......|...||
Mosquito   600 -LTARSPVHQHASLPAPPAPPVTSASAPPMMSSPPSGTGSPPAHLHPAQQPP 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sens-2	NP_723223.1	COG5048	<504..672	CDD:227381	72/187 (39%)
		C2H2 Zn finger	509..530	CDD:275368	6/20 (30%)
		SUF4-like	534..>589	CDD:411020	24/54 (44%)
		C2H2 Zn finger	538..558	CDD:411020	6/19 (32%)
		C2H2 Zn finger	538..558	CDD:275368	6/19 (32%)
		C2H2 Zn finger	566..586	CDD:411020	12/19 (63%)
		C2H2 Zn finger	566..586	CDD:275368	12/19 (63%)
		C2H2 Zn finger	594..614	CDD:275368	11/19 (58%)
		zf-H2C2_2	606..631	CDD:463886	11/24 (46%)
		C2H2 Zn finger	622..642	CDD:275368	9/19 (47%)
		C2H2 Zn finger	650..677	CDD:275368	11/46 (24%)
LOC1280253	XP_061514316.1	None