Protein Alignment sens-2 and ZFP3

DIOPT Version :10

• Sequence 1: NP_723223.1
• Gene: sens-2 / 33957
• FlyBaseID: FBgn0051632
• Length: 746
• Species: Drosophila melanogaster
• Sequence 2: NP_694563.1
• Gene: ZFP3 / 124961
• HGNCID: 12861
• Length: 502
• Species: Homo sapiens
• Alignment Length: 197
• Identity: 87/197 - (44%)
• Similarity: 112/197 - (56%)
• Gaps: 15/197 - (7%)

  Fly   484 SPHLHHFHHMAAKWPGLHQFSDLYSCMKCEKMFSTPHGLEVHSRRTHHGKKPYACELCNKTFGHE 548
            |.||.|.|.       :|.....|.|.:|.|.||....|.:| :|.|.|:|||.|..|.|||...
Human   209 SSHLIHHHR-------IHTGERPYKCEECGKAFSQNSALILH-QRIHTGEKPYECNECGKTFRVS 265

  Fly   549 VSLSQHRAVHNVEKVFECKQCGKRFKRSSTLSTHLLIHSDTRPYPCNYCGKRFHQKSDMKKHTYI 613
            ..|.||:.:|..|:..||.:|||.||.||.|..|..||:..:||.||.|||.|.|.|::.:|..|
Human   266 SQLIQHQRIHTEERYHECNECGKAFKHSSGLIRHQKIHTGEKPYLCNECGKGFGQSSELIRHQRI 330

  Fly   614 HTGEKPHKCQVCGKAFSQSSNLITHSRKHTGYKPFSCKLCHKAFQRKVDLRRHKETQHTDLRVHL 678
            |||:||::|..|||.|.|:|.:|.|.|.|||.||:.||.|.|||:...:|.||:       |:|.
Human   331 HTGDKPYECNECGKTFGQNSEIIRHIRIHTGEKPYVCKECGKAFRGNSELLRHE-------RIHT 388

  Fly   679 GK 680
            |:
Human   389 GE 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sens-2	NP_723223.1	COG5048	<504..672	CDD:227381	78/167 (47%)
		C2H2 Zn finger	509..530	CDD:275368	8/20 (40%)
		SUF4-like	534..>589	CDD:411020	26/54 (48%)
		C2H2 Zn finger	538..558	CDD:411020	8/19 (42%)
		C2H2 Zn finger	538..558	CDD:275368	8/19 (42%)
		C2H2 Zn finger	566..586	CDD:411020	10/19 (53%)
		C2H2 Zn finger	566..586	CDD:275368	10/19 (53%)
		C2H2 Zn finger	594..614	CDD:275368	9/19 (47%)
		zf-H2C2_2	606..631	CDD:463886	12/24 (50%)
		C2H2 Zn finger	622..642	CDD:275368	10/19 (53%)
		C2H2 Zn finger	650..677	CDD:275368	10/26 (38%)
ZFP3	NP_694563.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	47..103
		COG5048	139..495	CDD:227381	87/197 (44%)
		C2H2 Zn finger	143..163	CDD:275368
		C2H2 Zn finger	171..191	CDD:275368
		C2H2 Zn finger	199..219	CDD:275368	5/16 (31%)
		C2H2 Zn finger	227..247	CDD:275368	8/20 (40%)
		C2H2 Zn finger	255..275	CDD:275368	8/19 (42%)
		C2H2 Zn finger	283..303	CDD:275368	10/19 (53%)
		C2H2 Zn finger	311..331	CDD:275368	9/19 (47%)
		C2H2 Zn finger	339..359	CDD:275368	10/19 (53%)
		C2H2 Zn finger	367..387	CDD:275368	10/26 (38%)
		C2H2 Zn finger	395..415	CDD:275368
		C2H2 Zn finger	423..443	CDD:275368
		C2H2 Zn finger	451..471	CDD:275368
		C2H2 Zn finger	479..499	CDD:275368