Protein Alignment Daao2 and daao-1

DIOPT Version :10

• Sequence 1: NP_609075.1
• Gene: Daao2 / 33955
• FlyBaseID: FBgn0031860
• Length: 341
• Species: Drosophila melanogaster
• Sequence 2: NP_500234.3
• Gene: daao-1 / 3565775
• WormBaseID: WBGene00022076
• Length: 322
• Species: Caenorhabditis elegans
• Alignment Length: 1341
• Identity: 227/1341 - (16%)
• Similarity: 380/1341 - (28%)
• Gaps: 538/1341 - (40%)

  Fly    29 ETNKVNGQ----HIDSFNYFINVDIKKIVQANQEVKSDADPCFYLKYLNVHVGKPDVEEGFNNTK 89
            |...|.|:    |.:..|.....:.......||..|...|...:..|..           .|.:|
 Worm   141 ENKSVEGERNLRHPNRQNRTSESERSSKAHTNQNTKETEDSAIFRPYAR-----------RNRSK 194

  Fly    90 STTPHECRLRDMTYSAPITVDIEYTRG---TQRVVRNGLLIGRMPIMLRSSNCV--LTGKSDYQL 149
            .:       ||...|:  :.|:...||   |...:|.|.:.|:        .|:  ...:.|...
 Worm   195 IS-------RDPARSS--STDLVQNRGGLATSISIRRGSVEGK--------GCIPEAANQKDMHT 242

  Fly   150 SKVNECPMDPGGYFIIRGTEKVILIQEQLSWNKMITE-DYNGVIQCQVTSSTHEKKSRTILLTKH 213
            :.|: ||       :...:...|:.:.::|.|.:.|: |...|::    .||  ..|:|.||...
 Worm   243 TSVS-CP-------VFANSNGNIVPKNRVSSNSLNTKVDGEPVVR----EST--AGSKTSLLKDE 293

  Fly   214 GRYYLKHNSMTEEIPVAIILKAMGIASDQEIMQLVGIDPET-----QKRFAPSL---------LE 264
            ..  :.::..:..:||.    ..|:|.::..:...|..|:.     ||..:..|         .|
 Worm   294 AD--ISYSKSSAYLPVG----ESGLAGEKAQLVSTGGSPKAATIAGQKNSSTQLNGLRDSTVEEE 352

  Fly   265 AANHKVFTQQRALEYMGSKLIAKRFTTAATKYKTTADEARDLL---------------------- 307
            :..::..|....||...|.         |...:...|..|||.
 Worm   353 SLTNRGATGTNGLESESSH---------ANNVEVNVDNERDLYKVDKLDSDEISMQKTLRVEGLL 408

  Fly   308 ------------------ATTILAHVPVPSFNFQVKAIYVALMIRRVMAAELDRSAVDDRDYYGN 354
                              :|||::.. :|....|:|::.:.....| ..||:.   ..::.....
 Worm   409 DQTVGEMTKTKIEDETGQSTTIISEC-IPECEMQMKSVKIENQSHR-STAEMQ---TKEKSSETE 468

  Fly   355 KRLE----------LAGSLLS---------------------LMFEDLFKRFNWELKMIADKNIP 388
            |||:          ..||:||                     .:...|....:.|    |.|:.|
 Worm   469 KRLQDGLVVLENDSKVGSILSENPSSTLCSGIPQASVDTSSCTVGNSLLSGTDIE----ALKHQP 529

  Fly   389 KIKAAQFDVGKH---MREALI--------------TAGLET--------AISTGNWTIKRFKMER 428
            ...|...|..|.   :.||.|              ||.:|.        .:....|....|..||
 Worm   530 SSDAVMLDTVKEDAILEEARIIQAKKKRIAELSCGTAPVEVREKSQWDFVLEEMAWLANDFAQER 594

  Fly   429 ----AGVTQVLSRLSYISALGMMTRVNSQFEKTRKVSGPRSLQPSQWGMLCPSDTP---EGEACG 486
                ....|:..|::....|....|  :|..|.:|::...|....|:.....::.|   |..:.|
 Worm   595 LWKMTAAAQICHRVALTCQLRFEER--NQHRKLKKIASVLSNAILQFWSSVEAEVPGELEETSLG 657

  Fly   487 LVKNLALMTHITTEVDEEPVIRLAYNAGVEDIRLLGGETINNPKVFMVFINGNILGVTIAYRRLV 551
            :||
 Worm   658 IVK-------------------------------------------------------------- 660

  Fly   552 EVFRMMRRRGLIGAFVSIHTSFTQRCVYIHTDGGRLCRPYIIVQAGRPLYLDVNEENDSFIAYQE 616
                              .|.....|:     .||.|     :.||      |.|....|:.|..
 Worm   661 ------------------ETCQESNCL-----NGRRC-----LAAG------VKEYASRFLKYNN 691

  Fly   617 RDIDPEKTTHLEIEPFTLLGVCAGLVPYPHHNQSPRNTYQCAMGKQAMGIIGYNQKNRIDTLMYN 681
            ..|.                         :|:.:| :|.......:.:.|...:|.... :|.|:
 Worm   692 SSIS-------------------------YHSAAP-STPDNMCDPEILDISMVDQLTEA-SLFYS 729

  Fly   682 IVYPQSPM-VRSRTIE--LTNFDKLPAGQNATVAVMSYSGYDIEDALILNKASIDRGYGRCLVY- 742
            :  |...| |..::||  ||..:|..:.....|   ..|.||....:..|..:.|...|....|
 Worm   730 V--PSGAMEVYLKSIESHLTRCEKSGSSMQEEV---DTSAYDTAGDIGYNVTAFDEDEGETSTYY 789

  Fly   743 ---------------KNSKCTIKRYSNQTFDRIMG---PMKDGVTG----KIIAKHECLDTDGIV 785
                           |..|..:|.:|.:::|  :|   |..:...|    .::||.    .|..:
 Worm   790 LPGAFESSRSFNISHKKRKNLMKSHSARSYD--LGDDLPYVNNTGGSNSSSLMAKR----PDSNI 848

  Fly   786 SPGE------RLTCKQTMVNKEMPAVKSNNPIEQKESGQQPIAYSARVLVSTNNEEEFLVKILLR 844
            :.|.      |...:|.:|:....|...|.|:..|..            .|:.:...|
 Worm   849 NAGSVPTRRVRTASRQRVVSPFGCATTGNLPVPSKTD------------ASSGDTSSF------- 894

  Fly   845 QTRRPEIGDKFSSRHG----QKGV----------------------------------------- 864
                   .|::||.||    |||.
 Worm   895 -------QDEYSSLHGGSAVQKGTEVESSVNFEKLLPYDMAETSGRPKKKKKTHQGSAYDQTWHL 952

  Fly   865 -TGLIVEQED----LPFNDYGMSPDMVMNPHGFPSRMTVGKTLELLGSKAGVLEGKFHYGTAFGG 924
             ..:.|||:|    .|.|::.|:.  :..||....:.|..:          ::|..|.......|
 Worm   953 DPSVHVEQKDHWKKRPENNFDMNG--LYGPHSAKKQKTTKQ----------LVENNFDMAIPHTG 1005

  Fly   925 SKCSDLQDELF-----NHGFNYLG---KDVFYSGI--------TGEP--------LEVYIYS-GP 964
            |..|....::.     |....::|   :.....|:        :|.|        |.|.::. ||
 Worm  1006 SIPSPAASQMSNMSNPNKSIKFIGGRDRGRKIKGLKISPGQHGSGNPWSLFEDQALVVLVHDMGP 1070

  Fly   965 VYYQKLKHMVQDKMHARARGPRAVLTRQPTQGRSR------------------------------ 999
            .:     .::.|.|::..:  ...:.|.||:.:.|
 Worm  1071 NW-----ELISDAMNSTLK--IKCIYRNPTECKDRHKILMDKTAGDGADSAEDSGNSQSYPSTLP 1128

  Fly  1000 ---EGGLR------LGEMERDCLISYGASM-LIMERLMI--SSDAFDVDVCNVCGRLAYSSWCHN 1052
               :|..|      .|.||.|.|.|:...: ||.::|..  :.....|.|.:....:.:||
 Worm  1129 GIPKGSARQLFQRLQGPMEEDTLKSHFEKICLIGKKLHYRKTQSVIGVSVVSFVHGIQFSS---- 1189

  Fly  1053 CRSSASVSTISMP------YACK--LLFQE---LTSMNIVP 1082
            |..:....::.:|      |:||  |.|.|   ..|..|||
 Worm  1190 CTGAGISQSLDIPGLHVSKYSCKSWLGFPENDGRDSKQIVP 1230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Daao2	NP_609075.1	DAO	4..325	CDD:426168	63/359 (18%)
daao-1	NP_500234.3	DAO	3..310	CDD:426168	41/216 (19%)