DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nrv2 and atp1b1b

DIOPT Version :9

Sequence 1:	NP_001014475.1	Gene:	nrv2 / 33953	FlyBaseID:	FBgn0015777	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_571746.1	Gene:	atp1b1b / 64273	ZFINID:	ZDB-GENE-001127-4	Length:	302	Species:	Danio rerio

Alignment Length:	315	Identity:	82/315 - (26%)
Similarity:	126/315 - (40%)	Gaps:	49/315 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 PPERPKKKSLKQMVYDSEDNSYFGRSMDSWAKIGIFYVAFYGVLAALVAICMWAFFQTLDPRIPK 83
            |.:.......|:.|::||...:.||:..|||||.:||:.|||.||.:....:.....||....|.
Zfish     2 PAQNKDDGGWKKFVWNSEKKEFLGRTGGSWAKIFLFYLIFYGCLAGIFIGTIQILLLTLSDYKPT 66

  Fly    84 WTLDRSLIGTNPGLGFRPLPPVDNVESTLIWYKGTQHENYKHWTDSLDDFLAVYKVPGLTPGRGQ 148
            |. ||.   ..|||...|......:...|     ....::.::...:.:||..|.......  ..
Zfish    67 WQ-DRV---APPGLTHFPRSDKSEIAINL-----DDEVSFLNYVKVMREFLTSYDQEKQLD--NM 120

  Fly   149 NIYNC-----DYNQPPPKGQV-CDVDI-------KTW-SPCT--KENNYSYHKSAPCIFLKLNKI 197
            ...||     ||..   :|.: .||.:       :.| .||:  .:..:.:.:..||:..|||:|
Zfish   121 QFENCGESPLDYKN---RGDLESDVGVRRACQFSREWLGPCSGLDDPYFGFKEGKPCLIAKLNRI 182

  Fly   198 YGWIPEYYNRSNDLPANMPASLKTYIAEVE-KTQPEKLNTIWVSCEGENPADQENIGAVNYLPI- 260
            ..:.|:           .|.|.::...||: |.||   ..|.:.|..:...|...:|.|.|...
Zfish   183 VNFRPK-----------PPVSNESIPEEVQHKVQP---YLIPIHCTNKKEEDAGKLGEVRYYGFG 233

  Fly   261 RGFPGYFYPYQNS---EGYLSPLVAVHFQRPKRGIIINVECRAWARNIIHDRKER 312
            .|||..:|||...   ..||.||||:.|........:.:||:.:..||.:..|:|
Zfish   234 GGFPLQYYPYYGKLLHPQYLQPLVAIQFLNITPNTDMRIECKVYGENIYYHDKDR 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nrv2	NP_001014475.1	Na_K-ATPase	24..317	CDD:278704	81/310 (26%)
atp1b1b	NP_571746.1	Na_K-ATPase	5..301	CDD:298651	81/312 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	125	1.000	Domainoid score	I5399
eggNOG	1	0.900	-	-		E1_KOG3927
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	125	1.000	Inparanoid score	I4678
OMA	1	1.010	-	-		QHG45736
OrthoDB	1	1.010	-	-		D422722at33208
OrthoFinder	1	1.000	-	-		FOG0000357
OrthoInspector	1	1.000	-	-		mtm6361
orthoMCL	1	0.900	-	-		OOG6_104632
Panther	1	1.100	-	-	O	PTHR11523
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X254
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.840