DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nrv2 and atp1b1a

DIOPT Version :9

Sequence 1:	NP_001014475.1	Gene:	nrv2 / 33953	FlyBaseID:	FBgn0015777	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_571743.3	Gene:	atp1b1a / 64267	ZFINID:	ZDB-GENE-001127-3	Length:	306	Species:	Danio rerio

Alignment Length:	318	Identity:	84/318 - (26%)
Similarity:	125/318 - (39%)	Gaps:	72/318 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 KQMVYDSEDNSYFGRSMDSWAKIGIFYVAFYGVLAALVAICMWAFFQTLDPRIPKWTLDRSLIGT 93
            |..:::|:...:.||:..||.||.||||.|||.||.:....:.|...||....|.:. ||.   .
Zfish    12 KSFIWNSDKKEFLGRTGCSWLKIFIFYVIFYGCLAGIFIGTIQAMLLTLSNYKPTYQ-DRV---A 72

  Fly    94 NPGLGFRPLPPVDNVESTLIWYKGTQHENYKHWTDSLDDFLAVYKVPGLTPGRGQNIYNCDYNQP 158
            .|||...|.|  |..|   |.|.......|..:.:.:|.||              ..||.|..:.
Zfish    73 PPGLSHSPRP--DKAE---INYNINDESTYLPYVNHIDAFL--------------KAYNEDVQKD 118

  Fly   159 PPKGQVC---------------DVDI-------KTW-SPCT-----KENNYSYHKSAPCIFLKLN 195
            ..|.:.|               |..:       :.| ..|:     |..||.:....||:.:|||
Zfish   119 DTKFEECGDKPQFYTDRGELESDNGVRKACRFRREWLGECSGQKDEKLKNYGFDDGQPCLIVKLN 183

  Fly   196 KIYGWIPEYYNRSNDLPANMPASLKTYIAEVEKTQPEKL--NTIWVSCEGENPADQENIGAVNYL 258
            :|..::|.....::.:|              |..:| ||  |.|.:.|..:...:...:|.:.|.
Zfish   184 RIVNFMPRPPASNDSIP--------------EAVRP-KLQGNVIPIHCSSKREEEANLLGQIKYF 233

  Fly   259 PI-RGFPGYFYPYQN---SEGYLSPLVAVHFQRPKRGIIINVECRAWARNIIHDRKER 312
            .: .|||..:|||..   ...||.||||:.|......:.:.|||:.:..||.:..|:|
Zfish   234 GLGTGFPLQYYPYYGKLLQPQYLQPLVAIKFYNITTDVDVRVECKVYGENIDYSEKDR 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nrv2	NP_001014475.1	Na_K-ATPase	24..317	CDD:278704	84/318 (26%)
atp1b1a	NP_571743.3	Na_K-ATPase	8..303	CDD:298651	84/318 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	125	1.000	Domainoid score	I5399
eggNOG	1	0.900	-	-		E1_KOG3927
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	125	1.000	Inparanoid score	I4678
OMA	1	1.010	-	-		QHG45736
OrthoDB	1	1.010	-	-		D422722at33208
OrthoFinder	1	1.000	-	-		FOG0000357
OrthoInspector	1	1.000	-	-		mtm6361
orthoMCL	1	0.900	-	-		OOG6_104632
Panther	1	1.100	-	-	O	PTHR11523
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X254
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.840