Protein Alignment nrv2 and ATP4B

DIOPT Version :9

• Sequence 1: NP_001014475.1
• Gene: nrv2 / 33953
• FlyBaseID: FBgn0015777
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_000696.1
• Gene: ATP4B / 496
• HGNCID: 820
• Length: 291
• Species: Homo sapiens
• Alignment Length: 341
• Identity: 80/341 - (23%)
• Similarity: 128/341 - (37%)
• Gaps: 90/341 - (26%)

  Fly     9 IDGFQQYYSRPPERPKKKSLKQMVYDSEDNSYFGRSMDSWAKIGIFYVAFYGVLAALVAICMWAF 73
            ::.||:|...|                :.....||::..|..|.::|||||.|:..|.|:|::..
Human    14 MEEFQRYCWNP----------------DTGQMLGRTLSRWVWISLYYVAFYVVMTGLFALCLYVL 62

  Fly    74 FQTLDPRIPKWTLDRSLIGTNPGLGFRP-------LPPVDNVESTLIWYKGTQHENYKHWTDSLD 131
            .||:||..|.:. |:.   .:||:..||       |..|.||.....|...||         :|.
Human    63 MQTVDPYTPDYQ-DQL---RSPGVTLRPDVYGEKGLEIVYNVSDNRTWADLTQ---------TLH 114

  Fly   132 DFLAVYKVPGLTPGRGQNIYNC---------DYNQPPPKGQVCDVDIKTWSPCT--KENNYSYHK 185
            .|||     |.:|...::..||         .:..|......|.........|:  .:.|:.:.:
Human   115 AFLA-----GYSPAAQEDSINCTSEQYFFQESFRAPNHTKFSCKFTADMLQNCSGLADPNFGFEE 174

  Fly   186 SAPCIFLKLNKIYGWIPEYYNRSNDLPANMPASLKTYIAEVEKTQPEKLNTIWVSCEGENPADQE 250
            ..||..:|:|:|..::|     ||.....:..:.        ..||.:|.         .|..
Human   175 GKPCFIIKMNRIVKFLP-----SNGSAPRVDCAF--------LDQPRELG---------QPLQ-- 215

  Fly   251 NIGAVNYLPIRG-FPGYFYPYQNSEG---YLSPLVAVHFQRPKRGIIINVECRAWARNII----H 307
                |.|.|..| |..:::||...:.   |.:||||.......|...:.:.|:..|.::.    |
Human   216 ----VKYYPPNGTFSLHYFPYYGKKAQPHYSNPLVAAKLLNIPRNAEVAIVCKVMAEHVTFNNPH 276

  Fly   308 DRKERIGSVHYELLID 323
            |..|  |.|.::|.|:
Human   277 DPYE--GKVEFKLKIE 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nrv2	NP_001014475.1	Na_K-ATPase	24..317	CDD:278704	73/318 (23%)
ATP4B	NP_000696.1	Na_K_ATPase_bet	2..291	CDD:273446	80/341 (23%)
		immunoglobulin-like	194..291		26/122 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3927
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45736
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000357
OrthoInspector	1	1.000	-	-		mtm8622
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11523
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X254
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.920