Protein Alignment nrv2 and ATP1B2

DIOPT Version :9

• Sequence 1: NP_001014475.1
• Gene: nrv2 / 33953
• FlyBaseID: FBgn0015777
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_001669.3
• Gene: ATP1B2 / 482
• HGNCID: 805
• Length: 290
• Species: Homo sapiens
• Alignment Length: 326
• Identity: 93/326 - (28%)
• Similarity: 137/326 - (42%)
• Gaps: 69/326 - (21%)

  Fly    24 KKKSL-------KQMVYDSEDNSYFGRSMDSWAKIGIFYVAFYGVLAALVAICMWAFFQTLDPRI 81
            :|||.       |:.|::...:.:.||:..|||.|.:||:.|||.|.|:..:.||...||:....
Human     6 EKKSCGQVVEEWKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLTMWVMLQTVSDHT 70

  Fly    82 PKWTLDRSLIGTNPGLGFRP----LPPVDNVESTLIWYKGTQHENYKHWTDSLDDFLAVYKVPGL 142
            ||:. ||.   ..|||..||    |..:.||..|..|.:..|..|  .:.:..:|.:...|....
Human    71 PKYQ-DRL---ATPGLMIRPKTENLDVIVNVSDTESWDQHVQKLN--KFLEPYNDSIQAQKNDVC 129

  Fly   143 TPGRGQNIYNCDYNQPP------PKGQVCDVDIKTWSPCT---KENNYSYHKSAPCIFLKLNKIY 198
            .|||    |   |.||.      || :.|..:......|:   ...:|.|....||:|:|:|::.
Human   130 RPGR----Y---YEQPDNGVLNYPK-RACQFNRTQLGNCSGIGDSTHYGYSTGQPCVFIKMNRVI 186

  Fly   199 GWIPEYYNRSNDLPANMPASLKTYIAEVEKTQPEKLNTIWVSCEGENPADQENIGAVNYLPIRG- 262
                .:|..:|                      :.:|   |:|.|:...|.||:|.....|..|
Human   187 ----NFYAGAN----------------------QSMN---VTCAGKRDEDAENLGNFVMFPANGN 222

  Fly   263 FPGYFYPYQNSE---GYLSPLVAVHFQRPKRGIIINVECRAWARNIIHD--RKERIGSVHYELLI 322
            ....::||...:   .|..|||||.|......:.:|||||..|.||..|  |.:..|.|.::|.|
Human   223 IDLMYFPYYGKKFHVNYTQPLVAVKFLNVTPNVEVNVECRINAANIATDDERDKFAGRVAFKLRI 287

  Fly   323 D 323
            :
Human   288 N 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nrv2	NP_001014475.1	Na_K-ATPase	24..317	CDD:278704	90/318 (28%)
ATP1B2	NP_001669.3	Na_K_ATPase_bet	2..289	CDD:273446	93/326 (29%)
		immunoglobulin-like	193..290		34/121 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	139	1.000	Domainoid score	I4783
eggNOG	1	0.900	-	-		E1_KOG3927
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	139	1.000	Inparanoid score	I4506
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45736
OrthoDB	1	1.010	-	-		D422722at33208
OrthoFinder	1	1.000	-	-		FOG0000357
OrthoInspector	1	1.000	-	-		mtm8622
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11523
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X254
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	11	10.980