Protein Alignment nrv2 and ATP1B1

DIOPT Version :9

• Sequence 1: NP_001014475.1
• Gene: nrv2 / 33953
• FlyBaseID: FBgn0015777
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_001668.1
• Gene: ATP1B1 / 481
• HGNCID: 804
• Length: 303
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 92/317 - (29%)
• Similarity: 141/317 - (44%)
• Gaps: 55/317 - (17%)

  Fly    22 RPKKK---SLKQMVYDSEDNSYFGRSMDSWAKIGIFYVAFYGVLAALVAICMWAFFQTLDPRIPK 83
            |.|.|   |.|:.:::||...:.||:..||.||.:|||.|||.||.:....:.....|:....|.
Human     3 RGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPT 67

  Fly    84 WTLDRSLIGTNPGLGFRPLPPVDNVESTLIWYKGTQHENYKHWTDSLDDFLAVYK---------- 138
            :. ||.   ..||     |..:..::.|.|.::....::|:.:..::..||..||
Human    68 YQ-DRV---APPG-----LTQIPQIQKTEISFRPNDPKSYEAYVLNIVRFLEKYKDSAQRDDMIF 123

  Fly   139 -----VPGLTPGRGQNIYNCDYNQPPPKGQVCDVDIKTWSPCT--KENNYSYHKSAPCIFLKLNK 196
                 ||.....||      |:|....:.:||...::....|:  .:..|.|.:..|||.:|||:
Human   124 EDCGDVPSEPKERG------DFNHERGERKVCRFKLEWLGNCSGLNDETYGYKEGKPCIIIKLNR 182

  Fly   197 IYGWIPEYYNRSNDLPANMPASLKTYIAEVEKTQPEKLNTIWVSCEGENPADQENIGAVNYLPI- 260
            :.|:.|:       .|.|  .||:||  .|.|..|   |.:.|.|.|:...|::.:|.|.|..:
Human   183 VLGFKPK-------PPKN--ESLETY--PVMKYNP---NVLPVQCTGKRDEDKDKVGNVEYFGLG 233

  Fly   261 --RGFPGYFYPYQN---SEGYLSPLVAVHFQRPKRGIIINVECRAWARNIIHDRKER 312
              .|||..:|||..   ...||.||:||.|........|.:||:|:..||.:..|:|
Human   234 NSPGFPLQYYPYYGKLLQPKYLQPLLAVQFTNLTMDTEIRIECKAYGENIGYSEKDR 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nrv2	NP_001014475.1	Na_K-ATPase	24..317	CDD:278704	91/315 (29%)
ATP1B1	NP_001668.1	Na_K_ATPase_bet	1..303	CDD:273446	92/317 (29%)
		immunoglobulin-like	191..303		38/107 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	139	1.000	Domainoid score	I4783
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	139	1.000	Inparanoid score	I4506
Isobase	1	0.950	-	0	Normalized mean entropy	S5606
OMA	1	1.010	-	-		QHG45736
OrthoDB	1	1.010	-	-		D422722at33208
OrthoFinder	1	1.000	-	-		FOG0000357
OrthoInspector	1	1.000	-	-		mtm8622
orthoMCL	1	0.900	-	-		OOG6_104632
Panther	1	1.100	-	-	O	PTHR11523
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X254
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	12	11.930