Protein Alignment nrv2 and Atp1b2

DIOPT Version :10

• Sequence 1: NP_477168.1
• Gene: nrv2 / 33953
• FlyBaseID: FBgn0015777
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_036639.2
• Gene: Atp1b2 / 24214
• RGDID: 2171
• Length: 290
• Species: Rattus norvegicus
• Alignment Length: 326
• Identity: 92/326 - (28%)
• Similarity: 137/326 - (42%)
• Gaps: 69/326 - (21%)

  Fly    24 KKKSL-------KQMVYDSEDNSYFGRSMDSWAKIGIFYVAFYGVLAALVAICMWAFFQTLDPRI 81
            :|||.       |:.|::...:.:.||:..|||.|.:||:.|||.|.|:..:.||...||:....
  Rat     6 EKKSCGQVVEEWKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLTMWVMLQTVSDHT 70

  Fly    82 PKWTLDRSLIGTNPGLGFRP----LPPVDNVESTLIWYKGTQHENYKHWTDSLDDFLAVYKVPGL 142
            ||:. ||.   ..|||..||    |..:.|:..|..|.:..|..|  .:.:..:|.:...|....
  Rat    71 PKYQ-DRL---ATPGLMIRPKTENLDVIVNISDTESWDQHVQKLN--KFLEPYNDSIQAQKNDVC 129

  Fly   143 TPGRGQNIYNCDYNQPP------PKGQVCDVDIKTWSPCT---KENNYSYHKSAPCIFLKLNKIY 198
            .|||    |   |.||.      || :.|..:......|:   ...:|.|....||:|:|:|::.
  Rat   130 RPGR----Y---YEQPDNGVLNYPK-RACQFNRTQLGNCSGIGDPTHYGYSTGQPCVFIKMNRVI 186

  Fly   199 GWIPEYYNRSNDLPANMPASLKTYIAEVEKTQPEKLNTIWVSCEGENPADQENIGAVNYLPIRG- 262
                .:|..:|                      :.:|   |:|.|:...|.||:|.....|..|
  Rat   187 ----NFYAGAN----------------------QSMN---VTCVGKKDEDAENLGHFIMFPANGN 222

  Fly   263 FPGYFYPYQNSE---GYLSPLVAVHFQRPKRGIIINVECRAWARNIIHD--RKERIGSVHYELLI 322
            ....::||...:   .|..|||||.|......:.:|||||..|.||..|  |.:..|.|.::|.|
  Rat   223 IDLMYFPYYGKKFHVNYTQPLVAVKFLNVTPNVEVNVECRINAANIATDDERDKFAGRVAFKLRI 287

  Fly   323 D 323
            :
  Rat   288 N 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nrv2	NP_477168.1	Na_K-ATPase	18..317	CDD:459748	89/318 (28%)
Atp1b2	NP_036639.2	Na_K_ATPase_bet	2..289	CDD:273446	92/326 (28%)
		immunoglobulin-like. /evidence=ECO:0000250	193..290		34/121 (28%)