Protein Alignment nrv2 and ATP1B4

DIOPT Version :10

• Sequence 1: NP_477168.1
• Gene: nrv2 / 33953
• FlyBaseID: FBgn0015777
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_001135919.1
• Gene: ATP1B4 / 23439
• HGNCID: 808
• Length: 357
• Species: Homo sapiens
• Alignment Length: 318
• Identity: 79/318 - (24%)
• Similarity: 137/318 - (43%)
• Gaps: 64/318 - (20%)

  Fly    24 KKKSLKQMVYDSEDNSYFGRSMDSWAKIGIFYVAFYGVLAALVAICMWAFFQTLDPRIPKWTLDR 88
            |.:.:.:.::|.|...:..|:..||:.|.:.|..||..|||::.:||:..|.|:.|.||.:| :|
Human    85 KLQIMSEYLWDPERRMFLARTGQSWSLILLIYFFFYASLAAVITLCMYTLFLTISPYIPTFT-ER 148

  Fly    89 SLIGTNPGLGFRPLPPVDNVESTLIWYKGTQHENYKHWTDSLDDFLAVYK----------VPGLT 143
            .   ..||:..||.     ..|....:..::.:.::|:..||:.||..|.          .|
Human   149 V---KPPGVMIRPF-----AHSLNFNFNVSEPDTWQHYVISLNGFLQGYNDSLQEEMNVDCP--- 202

  Fly   144 PGRGQNIYNCDYNQPPPKGQVCDVDIKTWSPCT--KENNYSYHKSAPCIFLKLNKIYGWIPEYYN 206
            ||:   .:..|.|:...| :.|.........|:  ::..:.|....|||.||:|:|.|:
Human   203 PGQ---YFIQDGNEDEDK-KACQFKRSFLKNCSGLEDPTFGYSTGQPCILLKMNRIVGF------ 257

  Fly   207 RSNDLPANMPASLKTYIAEVEKTQPEKLNTIWVSCEGENPADQENIGAVNYLP-IRGFPGYFYPY 270
                                   :||..:.:.|||:.:. .|:.:|.:::|.| ...|...:|||
Human   258 -----------------------RPELGDPVKVSCKVQR-GDENDIRSISYYPESASFDLRYYPY 298

  Fly   271 QNS---EGYLSPLVAVHFQRPKRGIIINVECRAWARNIIHD--RKERIGSVHYELLID 323
            ...   ..|.|||||:||....:...:.|:|:...:.:|:|  ....:|.|.:.|.|:
Human   299 YGKLTHVNYTSPLVAMHFTDVVKNQAVPVQCQLKGKGVINDVINDRFVGRVIFTLNIE 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nrv2	NP_477168.1	Na_K-ATPase	18..317	CDD:459748	76/310 (25%)
ATP1B4	NP_001135919.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	15..80
		Na_K-ATPase	82..350	CDD:459748	76/310 (25%)