Protein Alignment nrv1 and ATP4B

DIOPT Version :10

• Sequence 1: NP_477167.1
• Gene: nrv1 / 33952
• FlyBaseID: FBgn0015776
• Length: 309
• Species: Drosophila melanogaster
• Sequence 2: NP_000696.1
• Gene: ATP4B / 496
• HGNCID: 820
• Length: 291
• Species: Homo sapiens
• Alignment Length: 313
• Identity: 73/313 - (23%)
• Similarity: 133/313 - (42%)
• Gaps: 58/313 - (18%)

  Fly    20 KKQTFSEMIYNPQEGTFFGRTGKSWSQLLLFYTIFYIVLAALFTICMQGLLSTISDTEPKWKLQD 84
            :.:.|....:||..|...|||...|..:.|:|..||:|:..||.:|:..|:.|:....|.:  ||
Human    13 RMEEFQRYCWNPDTGQMLGRTLSRWVWISLYYVAFYVVMTGLFALCLYVLMQTVDPYTPDY--QD 75

  Fly    85 SLIGTNPGLGFRPLSEQTERGSVIAFDGKKPAESDYWIEL---IDDFLRDYNHTEGRDMKHCGFG 146
            .|  .:||:..|| ....|:|..|.::   .:::..|.:|   :..||..|:.....|..:|...
Human    76 QL--RSPGVTLRP-DVYGEKGLEIVYN---VSDNRTWADLTQTLHAFLAGYSPAAQEDSINCTSE 134

  Fly   147 QVL------EPTDV---CVVNTDLFGGCS--KANNYGYKTNQPCIFLKLNKIFGWIPE-----VY 195
            |..      .|...   |....|:...||  ...|:|::..:||..:|:|:|..::|.     ..
Human   135 QYFFQESFRAPNHTKFSCKFTADMLQNCSGLADPNFGFEEGKPCFIIKMNRIVKFLPSNGSAPRV 199

  Fly   196 DKEEKDMPDDLKKVINETKTEERQQVWVSCNGHLGKDKENFQNIRYFPSQG-FPSYYYPFLN--- 256
            |....|.|.:|.:.:                           .::|:|..| |..:|:|:..
Human   200 DCAFLDQPRELGQPL---------------------------QVKYYPPNGTFSLHYFPYYGKKA 237

  Fly   257 QPGYLSPLVAVQFNSPPKGQMLDVECRAWAKNIQYSGSVRDRKGSVTFQILLD 309
            ||.|.:||||.:..:.|:...:.:.|:..|:::.::......:|.|.|::.::
Human   238 QPHYSNPLVAAKLLNIPRNAEVAIVCKVMAEHVTFNNPHDPYEGKVEFKLKIE 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nrv1	NP_477167.1	Na_K-ATPase	20..303	CDD:459748	71/305 (23%)
ATP4B	NP_000696.1	Na_K_ATPase_bet	2..291	CDD:273446	73/313 (23%)
		immunoglobulin-like	194..291		23/124 (19%)