Protein Alignment nrv1 and ATP1B1

DIOPT Version :10

• Sequence 1: NP_477167.1
• Gene: nrv1 / 33952
• FlyBaseID: FBgn0015776
• Length: 309
• Species: Drosophila melanogaster
• Sequence 2: NP_001668.1
• Gene: ATP1B1 / 481
• HGNCID: 804
• Length: 303
• Species: Homo sapiens
• Alignment Length: 313
• Identity: 105/313 - (33%)
• Similarity: 154/313 - (49%)
• Gaps: 47/313 - (15%)

  Fly     9 AKGEFEFPQPAKKQ-TFSEMIYNPQEGTFFGRTGKSWSQLLLFYTIFYIVLAALFTICMQGLLST 72
            |:|:      ||:: ::.:.|:|.::..|.||||.||.::||||.|||..||.:|...:|.:|.|
Human     2 ARGK------AKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLT 60

  Fly    73 ISDTEPKWKLQDSLIGTNPGLGFRPLSEQTERGSVIAFDGKKPAESDYWIELIDDFLRDYNHTEG 137
            ||:.:|.:  ||.:  ..|||...|..::||    |:|....|...:.::..|..||..|..:..
Human    61 ISEFKPTY--QDRV--APPGLTQIPQIQKTE----ISFRPNDPKSYEAYVLNIVRFLEKYKDSAQ 117

  Fly   138 RD---MKHCG-----------FGQVLEPTDVCVVNTDLFGGCSKANN--YGYKTNQPCIFLKLNK 186
            ||   .:.||           |........||....:..|.||..|:  ||||..:|||.:|||:
Human   118 RDDMIFEDCGDVPSEPKERGDFNHERGERKVCRFKLEWLGNCSGLNDETYGYKEGKPCIIIKLNR 182

  Fly   187 IFGWIPEVYDKEEKDMPDDLKKVINETKTEERQQVWVSCNGHLGKDKENFQNIRYF---PSQGFP 248
            :.|:.|:....|..:....:|...|...        |.|.|...:||:...|:.||   .|.|||
Human   183 VLGFKPKPPKNESLETYPVMKYNPNVLP--------VQCTGKRDEDKDKVGNVEYFGLGNSPGFP 239

  Fly   249 SYYYPF---LNQPGYLSPLVAVQFNSPPKGQMLDVECRAWAKNIQYSGSVRDR 298
            ..|||:   |.||.||.||:||||.:......:.:||:|:.:||.|  |.:||
Human   240 LQYYPYYGKLLQPKYLQPLLAVQFTNLTMDTEIRIECKAYGENIGY--SEKDR 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nrv1	NP_477167.1	Na_K-ATPase	20..303	CDD:459748	102/302 (34%)
ATP1B1	NP_001668.1	Na_K_ATPase_bet	1..303	CDD:273446	105/313 (34%)
		immunoglobulin-like	191..303		38/110 (35%)