DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nrv1 and Atp1b3

DIOPT Version :9

Sequence 1:	NP_001260163.1	Gene:	nrv1 / 33952	FlyBaseID:	FBgn0015776	Length:	309	Species:	Drosophila melanogaster
Sequence 2:	NP_037045.1	Gene:	Atp1b3 / 25390	RGDID:	2172	Length:	279	Species:	Rattus norvegicus

Alignment Length:	323	Identity:	95/323 - (29%)
Similarity:	146/323 - (45%)	Gaps:	86/323 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 KKQTFSE-------MIYNPQEGTFFGRTGKSWSQLLLFYTIFYIVLAALFTICMQGLLSTISDTE 77
            :|::|.:       .||||..|.|.|||.|||..:||||.:||..||||||..|..:|.|::|..
  Rat     5 EKKSFHQSLAEWKLFIYNPTSGEFLGRTSKSWGLILLFYLVFYGFLAALFTFTMWVMLQTLNDEV 69

  Fly    78 PKWKLQDSLIGTNPGLGFRPLSEQTERGSVIAFDGKKPAESDY------------WIELIDDFLR 130
            ||::  |.:  .:|||...|               |.|...||            ::|.:.:||:
  Rat    70 PKYR--DQI--PSPGLMVFP---------------KPPTALDYTYSMSDPHTYKKFVEDLKNFLK 115

  Fly   131 DYNHTEGRDMKHCGFGQVL--EPTD--VCVVNTDLFGGCSKAN--NYGYKTNQPCIFLKLNKIFG 189
            .|:..|.:::..|..|.:.  |..|  .|.....|...||..|  |:||...|||:.:|:|:|..
  Rat   116 PYSVEEQKNLTDCPGGALFHQEGPDYSACQFPVSLLQECSGVNDSNFGYSKGQPCVLVKMNRIIE 180

  Fly   190 WIPEVYDKEEKDMPDDLKKVINETKTEERQQVWVSCNGHLGKDKENFQNIRYFPSQG------FP 248
            .:|:       ..|                  :::|   :.|: ||..||..:|..|      ||
  Rat   181 LVPD-------GAP------------------YITC---ITKE-ENIANIVTYPDDGLIDLKYFP 216

  Fly   249 SYYYPFLNQPGYLSPLVAVQ--FNSPPKGQMLDVECRA-WAKNIQYSGSVRDR-KGSVTFQIL 307
              ||......||..||||||  |.:....:.:.:||:. ..:|:: :.:.||: .|.|:|:::
  Rat   217 --YYGKKRHVGYRQPLVAVQVIFGADATKKEVTIECQIDGTRNLK-NKNERDKFLGRVSFKVI 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nrv1	NP_001260163.1	Na_K-ATPase	20..303	CDD:278704	93/317 (29%)
Atp1b3	NP_037045.1	Na_K_ATPase_bet	1..279	CDD:273446	95/323 (29%)
Atp1b3	NP_037045.1	immunoglobulin-like. /evidence=ECO:0000250	186..279		30/116 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3927
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45736
OrthoDB	1	1.010	-	-		D422722at33208
OrthoFinder	1	1.000	-	-		FOG0000357
OrthoInspector	1	1.000	-	-		mtm9102
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11523
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X254
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.930