DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nrv1 and Atp1b2

DIOPT Version :9

Sequence 1:	NP_001260163.1	Gene:	nrv1 / 33952	FlyBaseID:	FBgn0015776	Length:	309	Species:	Drosophila melanogaster
Sequence 2:	NP_036639.2	Gene:	Atp1b2 / 24214	RGDID:	2171	Length:	290	Species:	Rattus norvegicus

Alignment Length:	320	Identity:	97/320 - (30%)
Similarity:	147/320 - (45%)	Gaps:	62/320 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 QPAKK------QTFSEMIYNPQEGTFFGRTGKSWSQLLLFYTIFYIVLAALFTICMQGLLSTISD 75
            |..||      :.:.|.::||:...|.||||.||:.:||||.:||..|.|:||:.|..:|.|:||
  Rat     4 QKEKKSCGQVVEEWKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLTMWVMLQTVSD 68

  Fly    76 TEPKWKLQDSLIGTNPGLGFRPLSEQTERGSVIAFDGKKPAESDYW---IELIDDFLRDYNHT-- 135
            ..||:  ||.|  ..|||..||   :||...||.    ..::::.|   ::.::.||..||.:
  Rat    69 HTPKY--QDRL--ATPGLMIRP---KTENLDVIV----NISDTESWDQHVQKLNKFLEPYNDSIQ 122

  Fly   136 --------EGRDMKHCGFGQVLEPTDVCVVNTDLFGGCS---KANNYGYKTNQPCIFLKLNKIFG 189
                    .||..:....|.:..|...|..|....|.||   ...:|||.|.|||:|:|:|::..
  Rat   123 AQKNDVCRPGRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDPTHYGYSTGQPCVFIKMNRVIN 187

  Fly   190 WIPEVYDKEEKDMPDDLKKVINETKTEERQQVWVSCNGHLGKDKENFQNIRYFPSQG-FPSYYYP 253
            :.                       ....|.:.|:|.|...:|.||..:...||:.| ....|:|
  Rat   188 FY-----------------------AGANQSMNVTCVGKKDEDAENLGHFIMFPANGNIDLMYFP 229

  Fly   254 FLNQP---GYLSPLVAVQFNSPPKGQMLDVECRAWAKNIQYSGSVRDR-KGSVTFQILLD 309
            :..:.   .|..|||||:|.:......::||||..|.||. :...||: .|.|.|::.::
  Rat   230 YYGKKFHVNYTQPLVAVKFLNVTPNVEVNVECRINAANIA-TDDERDKFAGRVAFKLRIN 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nrv1	NP_001260163.1	Na_K-ATPase	20..303	CDD:278704	94/309 (30%)
Atp1b2	NP_036639.2	Na_K_ATPase_bet	2..289	CDD:273446	97/320 (30%)
Atp1b2	NP_036639.2	immunoglobulin-like. /evidence=ECO:0000250	193..290		31/97 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	137	1.000	Domainoid score	I4756
eggNOG	1	0.900	-	-		E1_KOG3927
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H36075
Inparanoid	1	1.050	137	1.000	Inparanoid score	I4445
OMA	1	1.010	-	-		QHG45736
OrthoDB	1	1.010	-	-		D422722at33208
OrthoFinder	1	1.000	-	-		FOG0000357
OrthoInspector	1	1.000	-	-		mtm9102
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11523
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X254
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.980