DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nrv1 and Shbg

DIOPT Version :9

Sequence 1:	NP_001260163.1	Gene:	nrv1 / 33952	FlyBaseID:	FBgn0015776	Length:	309	Species:	Drosophila melanogaster
Sequence 2:	NP_035497.1	Gene:	Shbg / 20415	MGIID:	98295	Length:	403	Species:	Mus musculus

Alignment Length:	164	Identity:	36/164 - (21%)
Similarity:	55/164 - (33%)	Gaps:	72/164 - (43%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 GAKGEF---EFPQP-AKKQTFS-EMIYNPQEGTFFGR-----TGKSWSQLLLFYTIFYIVLAALF 62
            |...||   :.||| |...||| |:.:...:|:  |:     ||.:.|.|.:......:||:
Mouse   231 GTHAEFSLQDIPQPHADPWTFSLELGFKLVDGS--GQLLALGTGTNSSWLNIHLQNQSVVLS--- 290

  Fly    63 TICMQGLLSTISDTEPKWKLQDSLIGTNPGLGFRPLSEQTERGSVIAFDGKK------------- 114
                       |:.|||     .::..:.||   ||....:|..|:...|.|
Mouse   291 -----------SEAEPK-----VVLPLDVGL---PLQLTLDRVKVVLSQGPKMEVLSMSLLRPAS 336

  Fly   115 -----------------PAE--------SDYWIE 123
                             |.|        ||:|::
Mouse   337 LWRLWSHPQGHLSLGALPGESSSASFCLSDFWVQ 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nrv1	NP_001260163.1	Na_K-ATPase	20..303	CDD:278704	29/148 (20%)
Shbg	NP_035497.1	Laminin_G_1	76..206	CDD:333802
Shbg	NP_035497.1	LamG	225..369	CDD:389952	35/161 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3927
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900