DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nrv1 and atp1b4

DIOPT Version :9

Sequence 1:	NP_001260163.1	Gene:	nrv1 / 33952	FlyBaseID:	FBgn0015776	Length:	309	Species:	Drosophila melanogaster
Sequence 2:	XP_002664470.2	Gene:	atp1b4 / 100037383	ZFINID:	ZDB-GENE-070412-1	Length:	347	Species:	Danio rerio

Alignment Length:	313	Identity:	92/313 - (29%)
Similarity:	138/313 - (44%)	Gaps:	52/313 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 PQPAKKQTFSEMI-------YNPQEGTFFGRTGKSWSQLLLFYTIFYIVLAALFTICMQGLLSTI 73
            |:|..|:|..|.|       :|.:...|.||:|||||.:||||...||.|||:|..||..|:.:|
Zfish    61 PKPKPKRTLHEKIDDLKTYLWNAETKEFMGRSGKSWSLILLFYAALYIFLAAMFAGCMCCLMWSI 125

  Fly    74 SDTEPKWKLQDSLIGTNPGLGFRPLSEQTERGSVIAFDGKKPAESDYWIELIDDFLRDYNH-TEG 137
            |...|.:  .|.::  .||:...| ...|..|..|||:....:....:.:.::..|:.|:. .:.
Zfish   126 SPYAPTY--NDRVM--PPGMTMFP-HVDTAHGFDIAFNASDRSSWRRYAKTLEAHLKPYDDGLQS 185

  Fly   138 RDMKHCGFGQVLEPTDV--------CVVNTDLFGGCS--KANNYGYKTNQPCIFLKLNKIFGWIP 192
            |....|.........|:        |..|....|.||  :..::||...:|||.:|:|:|.|::|
Zfish   186 RRNIACKGNAYFMQEDLEESAERKACQFNRSSLGACSGLQDKDFGYSKGRPCILVKMNRILGYLP 250

  Fly   193 EVYDKEEKDMPDDLKKVINETKTEERQQVWVSCNGHLGKDKENFQNIRYFPSQGFPSYYYPF--- 254
                                   .:...|.|:|....| ..|....:::||:..|...|||:
Zfish   251 -----------------------GQGTPVNVTCGLKKG-STEVLGEVKFFPNPNFDLRYYPYYGK 291

  Fly   255 LNQPGYLSPLVAVQFNSPPKGQMLDVECRAWAKNIQYSGSVRDR-KGSVTFQI 306
            |....|.||||||||.:......|.::|:...|.| .:.|..|| .|||:|.:
Zfish   292 LRHVNYSSPLVAVQFLNVQHDTPLHIQCKLNGKGI-INDSPTDRFLGSVSFTL 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nrv1	NP_001260163.1	Na_K-ATPase	20..303	CDD:278704	88/304 (29%)
atp1b4	XP_002664470.2	Na_K-ATPase	71..340	CDD:278704	86/298 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	125	1.000	Domainoid score	I5399
eggNOG	1	0.900	-	-		E1_KOG3927
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	125	1.000	Inparanoid score	I4678
OMA	1	1.010	-	-		QHG45736
OrthoDB	1	1.010	-	-		D422722at33208
OrthoFinder	1	1.000	-	-		FOG0000357
OrthoInspector	1	1.000	-	-		mtm6361
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11523
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X254
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.980