DRSC/TRiP Functional Genomics Resources

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Protein Alignment LUBEL and ITT1

DIOPT Version :9

Sequence 1:NP_723214.2 Gene:LUBEL / 33950 FlyBaseID:FBgn0031857 Length:2892 Species:Drosophila melanogaster
Sequence 2:NP_013643.1 Gene:ITT1 / 854934 SGDID:S000004533 Length:464 Species:Saccharomyces cerevisiae


Alignment Length:325 Identity:75/325 - (23%)
Similarity:120/325 - (36%) Gaps:87/325 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly  2454 VIEDPAIL-----ARKYVDQELVTNIAEAQIAATLVSMKFSEDVALWAARECSDLDQAIAMLQQE 2513
            :|:|.|||     .||.:.|:......:....|||..:..|.    :....|.::::.:.|::..
Yeast   136 LIDDTAILLFPNGIRKCLTQDQYDLFKQISEEATLQKVSRSN----YHCCICMEMEKGVRMIKLP 196

  Fly  2514 CELCMNSYPMNQMVSMLKCLHKCCKQCAKSYFTVQITDRSINDCSCPFCKLPELSNEAQHEDEHL 2578
            ||        |..|.     |..|:.|||||||..|.:..|:...||.|:..||.         |
Yeast   197 CE--------NANVE-----HYLCRGCAKSYFTAMIQENRISSVRCPQCEYKELK---------L 239

  Fly  2579 EYFSNLD-------------IFLKSILDNDVHELFQRKLRDRSLLQDPNF-----KWCIQCSSGF 2625
            |.|.:..             .|||.::|.::.|.:::...:::..:...:     ..|.:|.|..
Yeast   240 EDFKSYKKMLKALFTPLIPVSFLKEVIDTELCERYEKMFYNQAATRLSKYCPYACVTCRRCDSWC 304

  Fly  2626 FARPKQKRLI-CPDCGSVTCAQCRKPWERQHEGSSC-----------EAYLE---WKRENDPELQ 2675
            ........:| |..|..|.|..|...|...:  :.|           |.||:   ...|...:|:
Yeast   305 TKEDLDDAMIQCQKCHFVFCFDCLHAWHGYN--NKCGKKVSLSTDIIEEYLDDTVTSYERKRKLE 367

  Fly  2676 AQ--------GVQEHLAQNGID------------CPKCKFRYSLARGGCMHFTCTQCKFEFCYGC 2720
            |:        .|.::||:..:|            |||||.....:. ||....|..|...||:.|
Yeast   368 AKYGRRVLELEVNDYLAEKMLDLAIKKEGSNLQRCPKCKVVVERSE-GCNKMKCEVCGTLFCFIC 431

  Fly  2721  2720
            Yeast   432  431

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LUBELNP_723214.2 Bbox1_HOIP 89..132 CDD:380873
Med15 <336..>483 CDD:312941
ZnF_RBZ 737..761 CDD:197784
RanBP2-type Zn finger 738..757 CDD:275376
HOIP-UBA 1036..1184 CDD:406963
PRK01741 1199..>1402 CDD:234977
rne <1482..1771 CDD:236766
Streccoc_I_II <2159..>2307 CDD:411384
RING-HC_RNF169 2513..2563 CDD:319465 17/49 (35%)
IBR 2598..2660 CDD:214763 11/67 (16%)
IBR <2690..2724 CDD:396187 12/31 (39%)
E3_UbLigase_RBR 2760..2858 CDD:407926
ITT1NP_013643.1 RING-HC_RNF169 179..233 CDD:319465 19/66 (29%)
IBR 272..334 CDD:214763 11/61 (18%)
IBR 385..433 CDD:396187 13/48 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - oto99663
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.910

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