DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11322 and CG2694

DIOPT Version :9

Sequence 1:	NP_609071.2	Gene:	CG11322 / 33949	FlyBaseID:	FBgn0031856	Length:	480	Species:	Drosophila melanogaster
Sequence 2:	NP_726827.1	Gene:	CG2694 / 31260	FlyBaseID:	FBgn0024991	Length:	825	Species:	Drosophila melanogaster

Alignment Length:	537	Identity:	301/537 - (56%)
Similarity:	362/537 - (67%)	Gaps:	59/537 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEIQKLPVKRHLPVTKGHGCVKNKCRRNLDEMSI-------------------QQFS-DSSSQSE 45
            |:..||..||..|.|||....|....:||:||:|                   |||. .|||||:
  Fly   291 MKTHKLGAKRRSPQTKGDVLAKKISYQNLNEMNISSNQPVVTRSGRVVVSRPNQQFDYSSSSQSK 355

  Fly    46 GDGEEDSN----DADDEEYQ-----QPEWTGRKR----------------------PPLVYLELG 79
            |||||||:    ||||:||:     |.:||.|||                      ||:||:|||
  Fly   356 GDGEEDSDEVSLDADDDEYEGEDFDQLKWTERKRRSFRNTSLAFSPDGSRSSPEATPPMVYVELG 420

  Fly    80 DKIIIVRNEPQPNVKLEDDVQLKTKMHKFLGLIPSRRKLYNPAVVYDMKPEDIE-----NINCVV 139
            .||:|:|::||||:.||||.:|||:||||||||||||||::|: .|:|...|||     ..:.|.
  Fly   421 GKIVIIRDKPQPNIVLEDDKELKTQMHKFLGLIPSRRKLFDPS-EYNMDRGDIEMDVYVPTSLVT 484

  Fly   140 N-SSHASAEPFTPSAEQPIRPKTMMTSTWSKLNLSNIDEPTPEESQAKSKNDFELWSIAFSFDQC 203
            | |..:|..|.||||...|..:|..||..|.||||:...||..|.|.|..:|..:......|.:.
  Fly   485 NPSPRSSPSPVTPSARSRIWQETTPTSICSNLNLSHTYTPTVNELQTKHMDDSIIQVNLDCFQKK 549

  Fly   204 TPDLHKEPIDLIDLPNEEQLAANCRRHKSSVPCLERHPKFYGFVRSLSPSISLNMCHPLALTYRQ 268
            |||..||||||.:||:::|||.|||||||.|..|||||.|||||:||.||:|||||||||||:|:
  Fly   550 TPDSVKEPIDLSELPSQKQLATNCRRHKSCVARLERHPHFYGFVQSLRPSVSLNMCHPLALTFRR 614

  Fly   269 NNFKICKVALAKVLFNIFNHAIFHCGLQVPIVWKHAMHTRCTCQLTVDAHGKRRAKILLLRSIKT 333
            .||:..||||||||||:||||:|||||||||||||||..|..|:|..||.|:|.|:||||.||.|
  Fly   615 TNFQQSKVALAKVLFNMFNHAVFHCGLQVPIVWKHAMKKRWKCELGFDASGRRTAQILLLHSIDT 679

  Fly   334 TAELIRCLLHEMCHVAAFVFNRELGHGDNCRRWAYQAKMALPEAPTIEDNCIDSFKYTCTMCTRC 398
            .||||..|||||||||||:||||||||||||||.||||||.||.|.:.: ||.||.|||:||:|.
  Fly   680 AAELIYLLLHEMCHVAAFLFNRELGHGDNCRRWTYQAKMAFPEVPALME-CIASFMYTCSMCSRS 743

  Fly   399 SYGVADLSMQNLRCYYCQFEVSVKNVWKSEMYDWTRSDPTMTPFKCFIWDRYLQLGEQGANTHST 463
            |||:|||...|:||||||||||||.|.|:.|::..|||.|||||||||.|:||:||.:|..|||:
  Fly   744 SYGLADLKSYNIRCYYCQFEVSVKPVSKANMHEGARSDRTMTPFKCFIRDKYLKLGAEGGVTHSS 808

  Fly   464 NMALLNEEFMRLNSTMD 480
            .||||||.|.::.:..:
  Fly   809 KMALLNEMFAKMTAATE 825

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11322	NP_609071.2	DUF45	278..422	CDD:302795	106/143 (74%)
CG2694	NP_726827.1	SprT	624..767	CDD:214794	106/143 (74%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455773
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3854
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	73	1.000	Inparanoid score	I5119
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0019318
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23099
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.890