DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment meng and Sbk2

DIOPT Version :9

Sequence 1:	NP_001285688.1	Gene:	meng / 33948	FlyBaseID:	FBgn0031855	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	NP_001139801.1	Gene:	Sbk2 / 381836	MGIID:	2685925	Length:	362	Species:	Mus musculus

Alignment Length:	285	Identity:	86/285 - (30%)
Similarity:	134/285 - (47%)	Gaps:	12/285 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 YNIEKTLAEGCFAKILLCRHRPTNTLVVLKAVHAELTTIKEFQKEFHYNYELSHHHHILSAYAVA 165
            |...:.|.:|.|.::||..||...|.:.||.:..:.|:::.|..||.....|..|..|::||.:.
Mouse    62 YEEVRPLGQGRFGRVLLVTHRQKGTPLALKQLPKQSTSLRGFLYEFCVGLSLGTHSAIVTAYGIG 126

  Fly   166 FQTMDYYVFAMEHAPYGDLASNIGPN-GLHENACKLISEQLSSALGFMHSKNLVHRDLKIENILV 229
            .::.:.|.|..|...:|||.:.|.|. ||.:.|.:..:.||:|||..:||..||:||||.||:||
Mouse   127 IESANSYSFLTEPVLHGDLITFIQPKVGLPQPAAQRCAAQLASALEHIHSHGLVYRDLKPENVLV 191

  Fly   230 FTPDFTRVKLCDFGATTKKGLLVH----KVKHTWTS-CVPPEQLELIKNERFQCLPVSDSWQFGI 289
            ..|...||||.|||.|..:|.|:.    .:.:|... |.||...|.:..:     |..|:|..|:
Mouse   192 CDPACQRVKLTDFGHTRPRGTLLRLTGPPIPYTAPELCAPPPLPEGLPIQ-----PSLDAWALGV 251

  Fly   290 LLYNILTGNPPWQSADWVKDQSYANFMKYE-QRKTTKVPDNFRRFSPRLMRCFRKYLSHDPEDRC 353
            |::.:|||..||.......|..:.:|:.:: ..:....|..:...||.........|...|..|.
Mouse   252 LIFCLLTGYFPWDQPLVEVDPFFEDFLIWQASGQPQDRPQPWYSLSPAADTLLWGLLDPHPRKRN 316

  Fly   354 KITEVAKYMKDRWVECRISTSKSAT 378
            .:..:..|:...|.:......:.||
Mouse   317 PVGSIKSYLGQPWKQREGEAEELAT 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
meng	NP_001285688.1	STKc_SBK1	107..366	CDD:270889	82/265 (31%)
Sbk2	NP_001139801.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26
		PKc_like	68..329	CDD:389743	82/265 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	329..362		3/13 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	165	1.000	Domainoid score	I3891
eggNOG	1	0.900	-	-		E1_KOG1345
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	169	1.000	Inparanoid score	I4135
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8812
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X768
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.820