DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment meng and Sbk1

DIOPT Version :9

Sequence 1:	NP_001285688.1	Gene:	meng / 33948	FlyBaseID:	FBgn0031855	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	NP_671476.1	Gene:	Sbk1 / 113907	RGDID:	628713	Length:	417	Species:	Rattus norvegicus

Alignment Length:	322	Identity:	106/322 - (32%)
Similarity:	161/322 - (50%)	Gaps:	45/322 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 PGAASVSRRSSIYKKPDKNDGGQIHLIPDVELPLMT---------------FADQYNIEKTLAEG 110
            ||||.|                     |...:||:|               ....|.:.:.|.:|
  Rat    19 PGAAPV---------------------PGAGVPLLTEDMQALTLRTLAASDVTKHYELVRELGKG 62

  Fly   111 CFAKILLCRHRPTNTLVVLKAVHAELTTIKEFQKEFHYNYELSHHHHILSAYAVAFQTMDYYVFA 175
            .:.|:.|..::.|.|.:.||.|:...|.:|.|.:|......||....|:..:.|.|:|.:.||||
  Rat    63 TYGKVDLVAYKGTGTKMALKFVNKSKTKLKNFLREVSITNSLSSSPFIIKVFDVVFETEECYVFA 127

  Fly   176 MEHAPYGDLASNIGPN-GLHENACKLISEQLSSALGFMHSKNLVHRDLKIENILVFTPDFTRVKL 239
            .|:||.|||...|.|. ||.|:..|...:||..||.||||:.|||||:|.||:|:|..:..||||
  Rat   128 QEYAPAGDLFDIIPPQVGLPEDTVKRCVQQLGLALDFMHSRQLVHRDIKPENVLLFDRECRRVKL 192

  Fly   240 CDFGATTKKGLLVHKVKHTWTSCVP---PEQLELIKNERFQCLPVSDSWQFGILLYNILTGNPPW 301
            .|||.|.:.|..|.:|..|    :|   ||..:..:.:.|......|.|.||:|::.:||||.||
  Rat   193 ADFGMTRRVGCRVKRVSGT----IPYTAPEVCQAGRADGFAVDTGVDVWAFGVLIFCVLTGNFPW 253

  Fly   302 QSADWVKDQSYANFMKYEQRKTTKVPDNFRRFSPRLMRCFRKYLSHDPEDRCKITEVAKYMK 363
            ::|... |..:..|:::::.:...:|..:|||:...:|.|::.|:.:||.|....||.:::|
  Rat   254 EAASGA-DAFFEEFVRWQRGRLPGLPSQWRRFTEPALRMFQRLLALEPERRGPAKEVFRFLK 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
meng	NP_001285688.1	STKc_SBK1	107..366	CDD:270889	96/261 (37%)
Sbk1	NP_671476.1	S_TKc	53..316	CDD:214567	97/267 (36%)
		STKc_SBK1	59..317	CDD:270889	96/261 (37%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	321..405
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348946
Domainoid	1	1.000	165	1.000	Domainoid score	I3818
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	169	1.000	Inparanoid score	I4051
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1221624at2759
OrthoFinder	1	1.000	-	-		FOG0002130
OrthoInspector	1	1.000	-	-		mtm9059
orthoMCL	1	0.900	-	-		OOG6_106722
Panther	1	1.100	-	-	O	PTHR24359
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X768
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.900