Protein Alignment TTLL3A and Ttll4

DIOPT Version :10

• Sequence 1: NP_609069.1
• Gene: TTLL3A / 33947
• FlyBaseID: FBgn0031854
• Length: 992
• Species: Drosophila melanogaster
• Sequence 2: NP_001414011.1
• Gene: Ttll4 / 690512
• RGDID: 1594742
• Length: 1198
• Species: Rattus norvegicus
• Alignment Length: 1082
• Identity: 215/1082 - (19%)
• Similarity: 355/1082 - (32%)
• Gaps: 362/1082 - (33%)

  Fly    30 ASATLAKKPVTPPAAPP-------------PTPSNRVVAPLTVPVIQLTPAQSDSPVKLARPATP 81
            :.||...|||:.|...|             |.|.:..|......|:      .|....:| |:||
  Rat   232 SQATDGLKPVSSPKIQPVSWHHSGGTGDCVPQPGDHKVPQSIATVL------DDVTAPMA-PSTP 289

  Fly    82 KETAISVPDHSNKENQPARTPPPSKSCPLGAPT-NYVARRTWITTERMNELRRKAQEAAKQNKIF 145
            ....||....::.:...:.....:..|.|...| :..|.:....||.:.:|..|..|...:....
  Rat   290 STLNISTASVASSQCSQSNFRREAHPCGLDENTDSQSATKEVHFTEAVRKLAAKGFEKMPRQGYQ 354

  Fly   146 TIRGCF--NSVRNALLMRGWVEKLDVHRKVMPAGQMTYEDLTQRLPKRKAGETRRQYVQKCERNI 208
            ..:.||  .|.:..||.|.        |:..|.       :.||.|:...|
  Rat   355 FEQACFVNPSFQWGLLNRS--------RRWKPL-------MGQRFPQEDIG-------------- 390

  Fly   209 MSRFLEHMPVDFLWTNRKEKCDYIDQAKNPGMTINKFHRAPFTSKEGL-----CSQLRDFHWFFE 268
                                   :|....||.          :...||     |::....|....
  Rat   391 -----------------------LDSGILPGA----------SDTLGLDSTVFCTKRISIHLLAS 422

  Fly   269 EGTAEMYFPRCYNVWSPEELGEFIENFKLTAC-----VAFLRAMLCKYH-----KQGSDA--VFS 321
            ........|.|.:|..|:.|||.......::.     ||.:...|...|     |:..:|  :.|
  Rat   423 HVHGLNPSPTCGSVVDPQLLGEDRAPVPPSSSLQPLGVAEVATRLSSVHLGQPGKEPEEAKDLNS 487

  Fly   322 CSGKIPYSAIDFAYKRL------------VEYIDSCQHNDIDFED-------------------- 354
            ||.|...|..|...|:|            :|  |||.|::.:.|:
  Rat   488 CSTKGDCSPTDLRPKQLEPEDSEDELGDGLE--DSCSHDENEEEEGDSECSSLSVVSPSESVAII 550

  Fly   355 -------------------------------PPKI-------------WEH-------------- 361
                                           .|.|             ||.
  Rat   551 SRNCVDLMSKSISNHEKVVRPALIYSLFPNVSPTIYFGTRDERVEKLPWEQRRLLRWKMSTVTPN 615

  Fly   362 ------------------DW----------DAF--LFQHQQLVNEDGRIQHDGGQRLEPMVKSCL 396
                              ||          ..|  :.:||:|.:..|..|.....||...:....
  Rat   616 IVKQTIGRSHFKISKRNDDWLGCWGHHMKSPGFRSIREHQKLNHFPGSFQIGRKDRLWRNLSRMQ 680

  Fly   397 SLVDKMKVHW-------PQYSL-------DGYQNMWIVKPANKCRGRGIILMDNLKKILGVVNLS 447
            |...|.:..:       ||.|.       ...:..|||||....||.||.::....:
  Rat   681 SRFGKKEFSFFPQSFILPQDSKLLRKAWESSSRQKWIVKPPASARGIGIQVIHKWSQ-------- 737

  Fly   448 IASKSRYVVQKYIERPLILFQTKFDIRQWFLITNTQPLVVWFYRESYLRFSSQEY-----SLSNH 507
            :..:...:||:|:.:|.::..:|||:|.:..:|:..||.::.:.:..:||:|.:|     ||||
  Rat   738 LPKRRPLLVQRYLHKPYLISGSKFDLRIYVYVTSYDPLRIYLFSDGLVRFASCKYSPSMKSLSN- 801

  Fly   508 HESVHLTNYAIQKKYT--NGKRDKRLPSENMWDCYSFQAYLRQIGKYNMWLERIFPGMRKAIVGC 570
             :.:|||||::.||..  ....|:.....:.|...:...||.|.|..:   :.|:..::..:|..
  Rat   802 -KFMHLTNYSVNKKNAEYQANADETACQGHKWALKALWNYLSQKGVNS---DAIWEKIKDVVVKT 862

  Fly   571 MLASQENMD-------RRP-NTFELFGADFMICENFYPWLIEINSSPDLGATTSVTARMCPQCLE 627
            :::|:..:.       ||| :..||||.|.|:.||..||::|:|.||.|.:.:.:...:..|.:.
  Rat   863 IISSEPYVTNLLKLYVRRPYSCHELFGFDIMLDENLKPWVLEVNISPSLHSNSPLDISIKGQMIR 927

  Fly   628 DVVKV----------VIDRRTDPKAELG---NFELAYRQVVPPTPAYMGLNLFVKGKQVLQKANH 679
            |::.:          ::...:.|.:..|   :...:.|:....||.:.       ..|.::||
  Rat   928 DLLNLAGFVLPNMEDILSSSSSPSSSSGSSTSLPSSPREKCQMTPEHF-------TAQKMKKA-- 983

  Fly   680 GGGHGHYYYQQQRKERSLATSSV-----------------YRQRSAI--IHPATSISRIHRAMPT 725
                  ||..|:..::...:|.:                 :.:|...  |.|:...||..|....
  Rat   984 ------YYLTQKVPDQDFYSSVLDVLTPDDVRVLVEMEDEFSRRGQFERIFPSRISSRYLRFFEQ 1042

  Fly   726 ---FN--ATEYMEKYMVEPLSS-----------------SRSSLCSQLPQKSPSAAPALTATPSG 768
               ||  .|::.:||....|..                 |.|:....||....:|:.. ..||:.
  Rat  1043 PRYFNILTTQWEQKYHGNKLKGVDLLRNWCYKGFHTGIVSDSAPLWSLPTSLMNASKG-DGTPNA 1106

  Fly   769 ATSSYILKQAGRSITQLLSATHKRNTGGSLSGEQVQSTALPPKRQRSCGP----RLSSTNPVEST 829
            .:.|...|...:|.::          |.|..|    .|:.|.|.|....|    .|||.|. |:|
  Rat  1107 VSRSDHNKSRKKSCSE----------GNSEDG----PTSKPKKSQAGLSPISRKTLSSKNN-ENT 1156

  Fly   830 EKKFK-----ILIKNYSSNGNE-NMQDARPEVANSATATAIS 865
            .|:.|     :.:..||..|:. :...|...:|:| ..||:|
  Rat  1157 SKQSKRSTQGLPVLKYSGQGSRLSASSASQSIADS-LLTAVS 1197

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL3A	NP_609069.1	TTL	342..640	CDD:397308	88/444 (20%)
Ttll4	NP_001414011.1	None