Protein Alignment TTLL3A and ttll4

DIOPT Version :10

• Sequence 1: NP_609069.1
• Gene: TTLL3A / 33947
• FlyBaseID: FBgn0031854
• Length: 992
• Species: Drosophila melanogaster
• Sequence 2: NP_001417762.2
• Gene: ttll4 / 558702
• ZFINID: ZDB-GENE-070912-313
• Length: 1069
• Species: Danio rerio
• Alignment Length: 815
• Identity: 170/815 - (20%)
• Similarity: 291/815 - (35%)
• Gaps: 250/815 - (30%)

  Fly     1 MQTRPSS---EPHRSRDQVTDGDRNRDQPQKCASATLAKKPVTP-----PA--APPPTPSNRVVA 55
            :.|.|::   :||...:.:           :..|..|.|:..:|     ||  :||.:.|.|.|.
Zfish   114 INTTPAACHRQPHWKLESL-----------RFKSGLLGKRAFSPQLSVCPACPSPPKSSSQRGVI 167

  Fly    56 PLTVPVIQLTPAQSDSPVKL-------ARPATPKETAISVPDHSNKE-NQPART----------- 101
            ...:|..|.:|..|:   ||       .||...|     :|..|.:| :.||..
Zfish   168 EKVMPTNQSSPWTSN---KLRNNSNGVVRPPNAK-----MPTFSKQEMHSPANVMSSCNGTFSRG 224

  Fly   102 ------PPPSKSCPL-----------GAPTNYVARRTWITTERMNEL----RRKAQEAAKQNKIF 145
                  .||..|.||           |.....:.:...|..:..|||    .....||.::....
Zfish   225 LKVDAMKPPQPSVPLKDISTDVILNHGKAVKDLRQFEKIKVDNANELDCCMGHGVNEAPQRVTKI 289

  Fly   146 TIRGCFNSVRNALLMRGWVEKLDVHRKVMPAGQMTYEDLTQRLPKRKAGETRRQYVQKCERNIMS 210
            :....||:  :|:|      |.:||     |.|.|...|: .:.:...|.     |..|..:..|
Zfish   290 SSEAEFNA--SAVL------KPNVH-----ARQRTLNGLS-NVKRITVGA-----VPVCLNDEES 335

  Fly   211 RFL---------------EHMPVD-------------------------FLWTN--------RKE 227
            ||.               |..|.|                         :..||        ::|
Zfish   336 RFAPMETNSALSFGIIADEKCPSDVVCIGGDCAIPEVTGHDISPQSPSVYTVTNQISAIQLTKEE 400

  Fly   228 KC-------------DYIDQAKNPGMTINKFHRAPFTSKEGLCSQLR-------DFHWFFEEGTA 272
            .|             |...:.:..||.::       ..:|.|..:|.       ||.......||
Zfish   401 SCQASPVGPLNGEAGDDNSEIQRQGMLLD-------VDEEELPDKLEDDFSDDDDFDDCDVSSTA 458

  Fly   273 EMYFPRCYNV---WSPEELGEFIENFKLTACVAFLRAMLCKYHKQGSDAVFSCSGK----IPYSA 330
            .|  ....||   .||:..|:.:|...|...:         :....|...||.:.:    :|...
Zfish   459 SM--AASSNVEEPISPDVEGDLVERSALVPSL---------FPHMPSTLYFSTANERVELLPAEQ 512

  Fly   331 IDFAYKRLVEYIDSCQHNDI---DFEDPPKIWEHDWDAFLFQHQ-----QLVNEDGRIQHDGGQ- 386
            :.....::.....:...|.|   .|:...|  .|||......|.     :.:.|..::.|..|.
Zfish   513 MKLLKWKITTVTPNVVKNTIFRSHFKATKK--SHDWLGCWGHHMKSPGFKAIREFQKLNHFPGSF 575

  Fly   387 ---RLEPMVKSCLSLVDKMKVHW--------------PQ--------YSLDGYQNMWIVKPANKC 426
               |.:.:.::    :.||:..:              ||        :...|.:..|||||....
Zfish   576 QIGRKDRLWRN----LSKMQARFGKREFGFFPRSFILPQDIKLLRKAWDDGGSKQKWIVKPPASA 636

  Fly   427 RGRGIILMDNLKKILGVVNLSIASKSRYVVQKYIERPLILFQTKFDIRQWFLITNTQPLVVWFYR 491
            ||.||.::....:        :..|...:||||:.:|.::...|||:|.:..:|:..||.::.:.
Zfish   637 RGIGIQVIHKWSQ--------MPRKRPLLVQKYLHKPYLISGNKFDLRIYVYVTSYDPLCIYIFN 693

  Fly   492 ESYLRFSSQEYSLSN---HHESVHLTNYAIQKK---YTNGKRDKRLPSENMWDCYSFQAYLRQIG 550
            :..:||:|.:||.|.   :::.:|||||::.||   |.:...||......    ::.:|..:.:|
Zfish   694 DGLVRFASCKYSSSMKTLNNKFMHLTNYSVNKKNSEYQSNSDDKACQGHK----WALKALWQYLG 754

  Fly   551 KYNMWLERIFPGMRKAIVGCMLASQENMD-------RRP-NTFELFGADFMICENFYPWLIEINS 607
            ...:....|:..::..::..::||...::       |.| :..||||.|.|:.||..||::|:|.
Zfish   755 SQGINTTLIWEKIKDMVIKTIIASDPYVNSLVKMHVRSPYSCHELFGFDIMLDENLKPWVLEVNI 819

  Fly   608 SPDLGATTSVTARMCPQCLEDVVKV---VIDRRTD 639
            ||.|.:.|.:...:..|.:.|::.:   |:..|.|
Zfish   820 SPSLHSNTPLDVSIKGQMIRDLLNLAGFVLPLRDD 854

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL3A	NP_609069.1	TTL	342..640	CDD:397308	83/349 (24%)
ttll4	NP_001417762.2	None