Protein Alignment TTLL3A and TTLL4B

DIOPT Version :10

• Sequence 1: NP_609069.1
• Gene: TTLL3A / 33947
• FlyBaseID: FBgn0031854
• Length: 992
• Species: Drosophila melanogaster
• Sequence 2: NP_722946.1
• Gene: TTLL4B / 33609
• FlyBaseID: FBgn0031574
• Length: 989
• Species: Drosophila melanogaster
• Alignment Length: 737
• Identity: 170/737 - (23%)
• Similarity: 271/737 - (36%)
• Gaps: 231/737 - (31%)

  Fly     5 PSSEPHRSRDQVTDGDRNRDQPQKCA--------SATLAKKPV---TPPAAPPP----TPSNRVV 54
            |..:..||    ....|.|..|:|.|        |...|::.:   |||.:..|    ||||
  Fly   130 PPGQKQRS----PPSPRKRLTPEKVANLGGGGGGSKVGAQRIIIRGTPPNSSTPKVAATPSN--- 187

  Fly    55 APLTVPVIQLTPAQSDSP-------VKLAR-PATPKETAISVPDHSNKENQPARTP------PPS 105
                |||:..:..||: |       :|.|| .|..|.||.:...:.|...:.|.:|      |||
  Fly   188 ----VPVVANSVLQSE-PYKKVQMLLKRAREEAFAKHTAGNSAANGNGPKRSAHSPPIQAKVPPS 247

  Fly   106 K-SCPL------GAPTNYVAR----RTWITTERMNELRRKAQEAAKQNKIFTIRGCFNSVRNALL 159
            . |||.      ..|:..|..    .:.::|::..|          ::::.|..|...|...||
  Fly   248 NMSCPSTQTLKPSPPSKIVVNSFHGSSMLSTQQQEE----------KSRLLTQNGLTKSAATAL- 301

  Fly   160 MRGWVEKLDVHRKVMPAGQMTYEDLTQRLPKRKAGETRRQYVQKCERNIMSRFLEHMPVDFLWTN 224
                             ....|..|....|                :|...:|  |.|
  Fly   302 -----------------ETSLYASLYANAP----------------QNSQPQF--HSP------- 324

  Fly   225 RKEKCDYIDQAKNPGMTINK--FHRAPFTSKEGLCSQLRDFHWFFEEGTAEMYFPRCYNVWSPEE 287
            |....|::  |...|:::||  .|......::..|:.:.|.:::.:..:.|.|      |.:|..
  Fly   325 RISGGDHV--ASYVGVSLNKGAGHDNDRKHEDDPCAAIDDINYYDDSDSEEEY------VGTPFF 381

  Fly   288 LGEFIENFKLTACVAFLRAMLCKYHKQGS--------------DAVFSCSGKIPYSAIDFAYKRL 338
            |.|  :|.: |......|.:..|...:.|              :|:.|.|          .:..:
  Fly   382 LEE--DNTE-TRQSKHTRLLPQKTPSKESVRTTDSEASVYFRPEAILSPS----------LFPHV 433

  Fly   339 VEYIDSCQHNDIDFEDP---------------PKIWEH--------------DWDAFLFQHQ--- 371
            ..|::...|.|.....|               |||.:.              ||.|...:|.
  Fly   434 PPYLNFTSHADKGPPMPAALHRVLKWKLSPVMPKIVKRVVLNSGFRIIKNTTDWMAVWEKHMKSP 498

  Fly   372 --QLVNEDGRIQHDGGQ----RLEPMVKSCLSLVDK---------------------MKVHWPQY 409
              :.:....:..|..|.    |.:.|.:|..:.:.|                     ::..||:.
  Fly   499 GFRTIRSHQKYNHIPGSFRIGRKDTMWRSIYNNMKKFGKKEFGFMQKSYIMPDDLESLRQVWPKN 563

  Fly   410 SLDGYQNMWIVKPANKCRGRGIILMDNLKKILGVVNLSIASKSR-YVVQKYIERPLILFQTKFDI 473
            :  .....|||||....||.||.:::...:.         .|.| .||||||||||::...|||:
  Fly   564 A--SKLTKWIVKPPASARGTGIRIVNKWSQF---------PKDRPLVVQKYIERPLLINDNKFDM 617

  Fly   474 RQWFLITNTQPLVVWFYRESYLRFSSQEYS--LSNHHE-SVHLTNYAIQKKYTNGKRDK------ 529
            |.:.::|:..||.::.|::...||:|.:||  |||..| .:|||||:|.|...|..:::
  Fly   618 RLYVVLTSINPLRIYMYKDGLARFASVKYSSELSNLDERCMHLTNYSINKFSQNYAKNEDFNACQ 682

  Fly   530 --RLPSENMWDCYSFQAYLRQIGKYNMWL---ERIFPGMRKAIVGCMLASQENMDRRPNTFELFG 589
              :...:::|.|..    .|.:....:|.   ..:..|:.....|.....::|::.|.|.|||||
  Fly   683 GHKWTLQSLWSCLE----NRGVNTKRLWATLRNLVIKGIVSGESGLNRMYRQNVNFRYNCFELFG 743

  Fly   590 ADFMICENFYPWLIEINSSPDL 611
            .|.::.||..|||:|||.||.|
  Fly   744 FDVLLDENLVPWLLEINISPSL 765

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL3A	NP_609069.1	TTL	342..640	CDD:397308	90/344 (26%)
TTLL4B	NP_722946.1	TTL	504..798	CDD:397308	80/277 (29%)