Protein Alignment TTLL3A and Ttll10

DIOPT Version :10

• Sequence 1: NP_609069.1
• Gene: TTLL3A / 33947
• FlyBaseID: FBgn0031854
• Length: 992
• Species: Drosophila melanogaster
• Sequence 2: NP_001355570.1
• Gene: Ttll10 / 330010
• MGIID: 1921855
• Length: 704
• Species: Mus musculus
• Alignment Length: 810
• Identity: 179/810 - (22%)
• Similarity: 280/810 - (34%)
• Gaps: 219/810 - (27%)

  Fly   100 RTPPPSK----SCPLGAPTNYVARRTWI---TTERMNELRRKAQEAAKQNKIFTIRGCFNSVRNA 157
            |.|.|||    .||:....:..|||...   ||......|..|...|.:|     |..|
Mouse    28 RLPSPSKVGAAVCPIQGLGHRAARRPRRGIGTTSASRVPRPGALMPATRN-----RPRF------ 81

  Fly   158 LLMRGWVEKLDVHRKVMPAGQMTYEDLTQRLPKRKAGETR--RQYVQKCERNIMSRFLEHMPVDF 220
                       :|.:..|             |:.:....|  |..:..|...:..
Mouse    82 -----------IHCRGQP-------------PRTRVSSKRSKRSRIHPCHTEVPG---------- 112

  Fly   221 LWTNRKEKCDYIDQAKNPGMT----------INKFHRAPFTSKEGLCSQLRDFH-------WFFE 268
             ||:.|:....:.:...|.::          ..:..|.|.||.:||..: .|..       :|:.
Mouse   113 -WTHEKQMGSSVKERLRPELSQLDQDADDLEEEEAARLPVTSPDGLLME-GDKQPSPGQGPFFYI 175

  Fly   269 EGT--AEMYFPRCYNVWSPEELGEFIENFKLTACVAFLRAMLCKYHKQGSDAVFSCSGKIPYSAI 331
            .||  |.:....|.:...........|::||..|....|...|.: ::|...:|    ::|.:
Mouse   176 GGTNGASIISNYCESKGWQRTQDSHCEDYKLKWCEIKCRDNYCSF-REGQQLLF----QLPNN-- 233

  Fly   332 DFAYKRLVEYIDSCQHNDIDFEDPPKIWEHDWDAFLFQHQQLVNEDGRIQHDGGQRLEPMVKSCL 396
                |.|...|...                   :.|.:|.:.:::            ..|:.|..
Mouse   234 ----KLLTTKIGLL-------------------SALREHARTLSK------------ARMLPSTQ 263

  Fly   397 SLVDKMKVHWPQ-YSLD------------GYQNMWIVKPANKCRGRGIILMDNLKK--ILGVVNL 446
            :.|.||:..:|: |.||            ....|||.||....:|:||.|:.:.::  .|.....
Mouse   264 TKVLKMEEFFPETYRLDIRDERQAFFALFDETQMWICKPTASNQGKGIFLIRSQEEAAALQAKTQ 328

  Fly   447 SIASKSRY-----------VVQKYIERPLILFQTKFDIRQWFLITNTQPLVVWFYRESYLRFSSQ 500
            ||.....|           |||:|::.||:|...|||:|.:.||....|.:| |:...|.|.:..
Mouse   329 SIEDDPIYRKMPFRAPQARVVQRYVQNPLLLDGKKFDVRSYMLIACAMPYMV-FFGHGYARLTLS 392

  Fly   501 EYSLSNHHESVHLTNYAIQKK---YTNGKRDKRLPSENMWDCYSFQAYL-----RQIGKYNMWLE 557
            .|:..:...|.||||..:|||   ||      .|....:|.......|:     :..|....|:.
Mouse   393 LYNPHSSDLSGHLTNQFMQKKSPLYT------LLKESTVWTMEHLNRYINDKFRKTKGLPRDWVF 451

  Fly   558 RIF-PGMRKAIVGCMLASQENMDRRPNTFELFGADFMICENFYPWLIEINSSPDLGATTSVTARM 621
            ..| ..|::.:..|.||.:..::.:...|:|.|.||:|.|||..||:|:|::|.|.....|...:
Mouse   452 TTFTKRMQQIMSHCFLAVKSKLECKLGYFDLIGCDFLIDENFKVWLLEMNANPALHTNCEVLKAV 516

  Fly   622 CP--------QCLEDVVKVVIDRRTDPKAELGNFELAYR----QVVPPTPAYMGLNLFVKGKQVL 674
            .|        ..||...|.:..::..|......|.|.|.    .:.|...:...||.........
Mouse   517 IPGVVIETLDLALETCQKSLHSQKMLPLLSQRRFVLLYNGETTDLWPRLASSRPLNRLPNPHPNP 581

  Fly   675 QKANHGGGHGHYYYQQQRKERSLATSSVYRQRSAIIHPATSISRIHRAMPTFNATEYMEKYMVEP 739
            ....|...|.|                  ...:...||..: :..|...||..|..       ..
Mouse   582 NPNPHPHPHPH------------------PNPNPHPHPHPN-ANPHPPRPTCEAAS-------SA 620

  Fly   740 LSSSRSSLCSQLP--QKSPSAAPALTATPSGATSSYILKQAGRSITQLLSATHKRNTGGSLSGEQ 802
            |||:|::: |:.|  :||..:..|...||   ..|.:...:|.||.:    :......|||.|.
Mouse   621 LSSARAAI-SERPGARKSMPSRGAPVCTP---RKSRLSDSSGSSIAE----SEPSLCSGSLEGS- 676

  Fly   803 VQSTALPPKRQRSCGPRLSSTNPVESTEKK 832
             :.||    |:.|.||      |.|..|::
Mouse   677 -RDTA----REPSLGP------PEEEREEE 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL3A	NP_609069.1	TTL	342..640	CDD:397308	84/340 (25%)
Ttll10	NP_001355570.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..32		2/3 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	46..125		20/124 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	137..170		7/33 (21%)
		CPSase_L_D2	270..525	CDD:473076	73/261 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	565..704		39/177 (22%)