Protein Alignment TTLL3A and Ttll5

DIOPT Version :10

• Sequence 1: NP_609069.1
• Gene: TTLL3A / 33947
• FlyBaseID: FBgn0031854
• Length: 992
• Species: Drosophila melanogaster
• Sequence 2: XP_006516052.1
• Gene: Ttll5 / 320244
• MGIID: 2443657
• Length: 1337
• Species: Mus musculus
• Alignment Length: 700
• Identity: 155/700 - (22%)
• Similarity: 259/700 - (37%)
• Gaps: 150/700 - (21%)

  Fly   356 PKIWEHDWDAFLFQHQQLVNEDGRIQHDGGQRLEPMVKSCLSLVDKMKVHWPQYSLDGYQNMWIV 420
            |:.:|      |.:..:|.....|:||..|.:...::.....|..:.......||.|  :..|||
Mouse   123 PRSYE------LTRKDRLYKNIIRMQHTHGFKAFHILPQTFLLPAEYAEFCNSYSKD--RGPWIV 179

  Fly   421 KPANKCRGRGIILMDNLKKILGVVNLSIASKSRYVVQKYIERPLILFQTKFDIRQWFLITNTQPL 485
            ||....||||:.|::|..:        |:.:...:|.:||..||::...|||:|.:.|:|:..||
Mouse   180 KPVASSRGRGVYLINNPNQ--------ISLEENILVSRYINNPLLIDDFKFDVRLYVLVTSYDPL 236

  Fly   486 VVWFYRESYLRFSSQEY---SLSNHHESVHLTNYAIQKK---YTNGKRDKRLPSENMWDCYSFQA 544
            |::.|.|...||::..|   |.:..::.:|||||::.||   |.:....:.....|.|...:...
Mouse   237 VIYLYEEGLARFATVRYDQGSKNIRNQFMHLTNYSVNKKSGDYVSCDDPEVEDYGNKWSMSAMLR 301

  Fly   545 YLRQIGKYNMWL-----ERIFPGMRKAIVGCMLASQENMDRRPNTFELFGADFMICENFYPWLIE 604
            ||:|.||....|     :.|...:..|.:....|.:..:..|.:.|||:|.|.:|.....|||:|
Mouse   302 YLKQEGKDTTALMAHVEDLIIKTIISAELAIATACKTFVPHRSSCFELYGFDVLIDNTLKPWLLE 366

  Fly   605 INSSPDLGATTSVTARMCPQCLEDVVKVV-----------------------------IDRRTDP 640
            :|.||.|.....:..::....:.|:..||                             ..:||.|
Mouse   367 VNLSPSLACDAPLDLKIKASMISDMFTVVGFVCQDPAQRTSNRSIYPSFESSRRNPFQKPQRTRP 431

  Fly   641 ----KAELGNFELAYRQVVPPTPAYMGLNLFVKGKQVLQKANHGGGHGHYYYQQQRKE---RSLA 698
                .||:.|...:.|:.||.......|.|.::..:||::...         :..|:.   |...
Mouse   432 LSASDAEMKNLVASAREKVPGKLGGSVLGLSMEEIKVLRRVKE---------ENDRRGGFIRIFP 487

  Fly   699 TSSVYRQRSAIIHPATSISRIHRAMPTFNATEYM-EKYMVEPLSSSRSSLCSQLPQKSPSAAPAL 762
            ||..:....:.:...||::             || ...:.:...:.|.||.:...:.|...||.|
Mouse   488 TSETWEIYGSYLEHKTSMN-------------YMLATRLFQDRGNPRRSLLTGRARVSTEGAPEL 539

  Fly   763 TATPSGATSSYILKQAGRSITQLLSATHKRNTGGSLSGEQVQSTALPPKRQRSCGPRLSSTNPVE 827
            ......:.:........|.:..|.....:|.:|        :..|:.||......|...:.....
Mouse   540 KVESMNSKAKLHAALYERKLLSLEVRKRRRRSG--------RLRAMRPKYPVIAQPAEMNIKTET 596

  Fly   828 STEKKFKILIKN---------YSSNGN--ENMQDARPE----VANSATATAISERKWR------- 870
            .:|::.::.:.|         ..|.|:  ||.....|.    |.||....|:...:|.
Mouse   597 ESEEEEEVGLDNDDEEQEASQEESAGSLGENQAKYTPSLTVIVENSPRDNAMKVAEWTNKGEPCC 661

  Fly   871 -----------SLRNIAATAGGSSNLAARSKGPPLIAPPSLPTRRLTRTKSEIDSTGMHAIGRTF 924
                       :|..|....|..|.:.||......:....:   |||
Mouse   662 KIEAQEPESKFNLMQILQDNGNLSKVQARLAFSAYLQHVQI---RLT------------------ 705

  Fly   925 GRKSNGPRLPISISVQALHRGEPIVAALKQATSELQLSQAQMMSPRTALA 974
             :.|.|..|..|.:.:...:.|.:|..||:|:|.||.| .:|:.|...||
Mouse   706 -KDSGGQTLSPSWAAKEDEQMELVVRFLKRASSNLQHS-LRMVLPSRRLA 753

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL3A	NP_609069.1	TTL	342..640	CDD:397308	83/323 (26%)
Ttll5	XP_006516052.1	TTL	117..395	CDD:397308	79/287 (28%)