Protein Alignment TTLL3A and Ttll10

DIOPT Version :10

• Sequence 1: NP_609069.1
• Gene: TTLL3A / 33947
• FlyBaseID: FBgn0031854
• Length: 992
• Species: Drosophila melanogaster
• Sequence 2: NP_001164004.1
• Gene: Ttll10 / 298692
• RGDID: 1560839
• Length: 727
• Species: Rattus norvegicus
• Alignment Length: 857
• Identity: 187/857 - (21%)
• Similarity: 296/857 - (34%)
• Gaps: 257/857 - (29%)

  Fly     1 MQTRPSSEPHRSRDQVTDGDRNRDQPQKCASATLAKKPVTPPAAPPPTPSNRVVAPLTVPVIQLT 65
            :.:|.....||.:|.:  |.|...:.::.     ||.|:.|||..|.......           :
  Rat    20 LNSRHRGHTHRGQDSL--GRRKLTRQRRD-----AKMPLHPPARRPHGHRRNG-----------S 66

  Fly    66 PAQSDSPVK-LARPATPKETAISVPDHSNKENQPARTPPPSKSCPLGAPTNYVARRTWITTERMN 129
            .||:::..: ..|.:.|:....:|.......::.||.|                ||...||....
  Rat    67 EAQTEATTQDTGRLSCPRRVGAAVCPIQGLGHRAARRP----------------RRGVGTTSASR 115

  Fly   130 ELRRKAQEAAKQNKIFTIRGCFNSVRNALLMRGWVEKLDVHRKVMPAGQMTYEDLTQRLPKRKAG 194
            ..|..|...|.:|     |..|                 :|.:|.|  ..|:  ::.:.|||  .
  Rat   116 APRPGALMPATRN-----RPRF-----------------IHYRVQP--PRTH--VSFKRPKR--S 152

  Fly   195 ETRRQYVQKCERNIMSRFLEHMPVDFLWTNRKEKCDYIDQAKNPGMT----------INKFHRAP 249
            .|.:.:.:             :|.   ||:.|.....:::...|.::          ..:..|.|
  Rat   153 RTHQSHTK-------------VPG---WTHEKRMGSSVEEGLRPELSQLEQDADNLGEEEAARLP 201

  Fly   250 FTSKEGLCSQLRDFH-------WFFEEGT--AEMYFPRCYNVWSPEELGEFIENFKLTACVAFLR 305
            .||..||..: .|.|       :|:..||  |.:....|.:...........|::||..|....|
  Rat   202 VTSLNGLLME-GDRHPNPGQGPFFYIGGTNGASIISNYCESKGWQRTQDSRCEDYKLKWCEIKCR 265

  Fly   306 AMLCKYHKQGSDAVFSCSGKIPYSAIDFAYKRLVEYIDSCQHNDIDFEDPPKIWEHDWDAFLFQH 370
            ...|.: ::|...:|    ::|.:      |.|...|...                   :.|.:|
  Rat   266 DNYCSF-REGQQLLF----QLPNN------KLLTTKIGLL-------------------SALREH 300

  Fly   371 QQLVNEDGRIQHDGGQRLEPMVKSCLSLVDKMKVHWPQ-YSLD------------GYQNMWIVKP 422
            .:.:::         .||.|   |..:.|.||...:|: |.||            ....|||.||
  Rat   301 ARTLSK---------ARLMP---STQAKVLKMDEFFPETYRLDIRDERQAFFTLFDETQMWICKP 353

  Fly   423 ANKCRGRGIILMDNLKK--ILGVVNLSIASKSRY-----------VVQKYIERPLILFQTKFDIR 474
            ....:|:||.|:.:.::  .|.....||.....|           |||:|::.||:|...|||:|
  Rat   354 TASNQGKGIFLIRSQEEAAALQAKTQSIEDDPIYRKMPFRAPQARVVQRYVQNPLLLDGKKFDVR 418

  Fly   475 QWFLITNTQPLVVWFYRESYLRFSSQEYSLSNHHESVHLTNYAIQKK------------------ 521
            .:.||....|.:| |:...|.|.:...|:..:...|.||||..:|||
  Rat   419 SYMLIACAMPYMV-FFGHGYARLTLSLYNPHSSDLSGHLTNQFMQKKSPLYMLLKDSTVWSMEHL 482

  Fly   522 --YTNGK--RDKRLPSENMWDCYSFQAYLRQIGKYNMWLERIFPGMRKAIVGCMLASQENMDRRP 582
              |.|.|  :.|.||.:  |...:|...::||..:                 |.||.:..::.:.
  Rat   483 NRYINDKFRKSKGLPRD--WVFTTFTKRMQQIMSH-----------------CFLAVKSKLECKL 528

  Fly   583 NTFELFGADFMICENFYPWLIEINSSPDLGATTSVTARMCP--------QCLEDVVKVVIDRRTD 639
            ..|:|.|.||:|.|||..||:|:||:|.|.....|...:.|        ..||...|.:..::..
  Rat   529 GYFDLIGCDFLIDENFKVWLLEMNSNPALHTNCEVLKEVIPGVVMETLDLALETCQKSLHSQKML 593

  Fly   640 PKAELGNFELAYRQVV-----------PPTPAYMGLNLFVKGKQVLQKANHGGGHGHYYYQQQRK 693
            |......|.|.|....           ||.            :.....:||.           |.
  Rat   594 PLQSQRRFVLLYNGETTDLWPRLGSSRPPI------------RLPYANSNHA-----------RS 635

  Fly   694 ERSLATSSVYRQRSAII-HPATSISRIHRAMP--TFNATEYMEKYMVEPLSSSRSSLCSQLPQKS 755
            ...:::||:...|..|. .||...|...|..|  ....:...:...|. :..|.:|:||.||:.|
  Rat   636 TCEISSSSLTSTRVTIADRPAARKSMSSRTAPICASRKSRLSDSGGVS-IEESETSVCSGLPEGS 699

  Fly   756 PSAA--PALTAT 765
            ..||  |:|..|
  Rat   700 RDAAREPSLGPT 711

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL3A	NP_609069.1	TTL	342..640	CDD:397308	88/353 (25%)
Ttll10	NP_001164004.1	PHA03247	<53..125	CDD:223021	18/98 (18%)
		CPSase_L_D2	323..576	CDD:473076	75/272 (28%)