Protein Alignment TTLL3A and TTLL3B

DIOPT Version :10

• Sequence 1: NP_609069.1
• Gene: TTLL3A / 33947
• FlyBaseID: FBgn0031854
• Length: 992
• Species: Drosophila melanogaster
• Sequence 2: XP_319095.4
• Gene: TTLL3B / 1279379
• VectorBaseID: AGAMI1_007827
• Length: 761
• Species: Anopheles gambiae
• Alignment Length: 820
• Identity: 247/820 - (30%)
• Similarity: 382/820 - (46%)
• Gaps: 110/820 - (13%)

  Fly    18 DGDRNRDQPQKCASATLAKKPVTP-PAAPPPTPSNRVVAPLTVPVIQLTPAQSDSPVK-LARPAT 80
            |..|..||..:.|...|.::.:.. ||..|| |||..............|...|.|:. |:||..
Mosquito    32 DYGRQLDQRFEQAPVQLTRRFLKGLPALEPP-PSNAHKRHQCPGPAGAAPGDDDRPLSPLSRPFP 95

  Fly    81 PKETAISVPDHSNKENQPARTPPPSKSCPLGAPTNYVARRTWITTERMNELRRKAQEAAKQNKIF 145
            ..:.:..|  |:.....|...||.........|.:...|.......:..:|:.|...|.::..||
Mosquito    96 QPKASQHV--HTFPRMAPRLQPPDDDEDANRTPKHKFFRNYSFDFLKQKQLKAKIASAVEKKHIF 158

  Fly   146 TIRGCFNSVRNALLMRGWVEKLDVHRKVMPAGQMTYEDLTQRLPKRKAGETRRQYVQKCERNIMS 210
            :|.|.:.::|.||..|.|:||......::  .::::..|.|:      .....:|    |..::|
Mosquito   159 SIVGHYPALRKALKTRHWLEKQTFRSALL--RELSHHALLQK------ASNGNEY----EEALVS 211

  Fly   211 RFLE-HMPVDFLWTNRKEKCDYIDQAKNPGMTINKFHRA-PFTSKEGLCSQLRDFHWFFEEGTAE 273
            ::|: ::|. |:|.:|..:....|:...|..:...:.|. .|..||.|...:...||..|||.||
Mosquito   212 KYLKPYLPY-FIWQHRNMRDCKQDRFYAPYRSRIHYERPYDFAVKENLIRLINASHWHQEEGFAE 275

  Fly   274 MYFPRCYNVWSPEELGEFIENFKLTACVAFLRAMLCKYHKQGSDAVFSCSGKIPYSAIDFAYKRL 338
            :.:||.|.:.:.:.:.:|.|:::||...:||..|     .:..:..|...|.:|...:..|.|.|
Mosquito   276 LDYPRTYLLDTEDIITKFQEDYQLTIVSSFLHHM-----AKHLEHAFDDEGTLPTDVLTTAMKYL 335

  Fly   339 VEYIDSCQHNDIDFED--PPKIWEHDWDAFLFQH--QQLVNEDGRIQHDGGQRLEPMVKSCLSLV 399
            ..|:...||.|||.|:  .|.:...:      :|  :||:..:.:.....|..:..:|.....||
Mosquito   336 RYYLGCAQHEDIDHEEFCEPLLTPEN------RHEMEQLLAGEAQFGSIPGYEVLSLVAQVKKLV 394

  Fly   400 DKMKVHWPQYSLDGYQNMWIVKPANKCRGRGIILMDNLKKILGVVNLSIASKSRYVVQKYIERPL 464
            .:....:|...:||.:||||:||.|:|||.||:|.::.:|:|..|:.:  ...:||.||||||||
Mosquito   395 HEAAKVFPDMKIDGIRNMWILKPGNRCRGLGIMLFNDDRKLLEHVDSN--PDVKYVAQKYIERPL 457

  Fly   465 ILFQTKFDIRQWFLITNT-QPLVVWFYRESYLRFSSQEYSLSNHHESVHLTNYAIQKKYTNGKRD 528
            ::..|||||||:||||.| ..|.||.||..||||||::::|.:..||:|||||:|||.|....|:
Mosquito   458 LIHCTKFDIRQYFLITYTNNVLKVWMYRNCYLRFSSRQFNLDDFSESIHLTNYSIQKNYAKEVRE 522

  Fly   529 --KRLPSENMWDCYSFQAYLRQIGKYNMWLERIFPGMRKAIVGCMLASQENMDRRPNTFELFGAD 591
              ..||:.|||....||.:|:.:.|...|..:|:|.|:|.|:..:.||.:.|....|.|||:|||
Mosquito   523 GADALPASNMWSLKRFQEHLQSLDKGFYWERKIYPDMKKNILAIVCASLDGMKMERNMFELYGAD 587

  Fly   592 FMICENFYPWLIEINSSPDLGATTSVTARMCPQCLEDVVKVVIDRRTDPKAELGNFELAYRQVVP 656
            ||:.|||...|||||:||||.::|.||:.:||..|||:||||||...|.:|..|.|||.:...:|
Mosquito   588 FMVTENFRTMLIEINTSPDLSSSTDVTSVICPAVLEDLVKVVIDNTKDKRAGTGQFELIHSLEIP 652

  Fly   657 PTPAYMGLNLFVKGKQVLQKANHGGGHGHYYYQQQRKERSLATSSVYRQRSAIIHPATSISRIHR 721
            ....| |..|.|.|:.:                 |.|.||
Mosquito   653 RVAPY-GYGLTVDGRSM-----------------QSKHRS------------------------- 674

  Fly   722 AMPTFNATEYMEKYMVEPLSSSRSSLCSQLPQKSPSAAPALTATPSGATSSYILKQAGRSITQLL 786
                        |..:.|:::|          ..|:.|...|:||..:|::     ||.::...:
Mosquito   675 ------------KSPLSPINTS----------TGPTVASTATSTPKRSTAA-----AGTTVATTV 712

  Fly   787 SATHKRNTGGSLSGEQVQSTALPPKRQRSCGPRLSSTNPV 826
            :.....:||.:....:....|.......|.|.:.|.|:.:
Mosquito   713 ATGGIISTGANGGNAKHSRYAASSSESSSRGSKTSLTSVI 752

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL3A	NP_609069.1	TTL	342..640	CDD:397308	132/304 (43%)
TTLL3B	XP_319095.4	None