Protein Alignment TTLL3A and TTLL5

DIOPT Version :10

• Sequence 1: NP_609069.1
• Gene: TTLL3A / 33947
• FlyBaseID: FBgn0031854
• Length: 992
• Species: Drosophila melanogaster
• Sequence 2: XP_313563.5
• Gene: TTLL5 / 1274440
• VectorBaseID: AGAMI1_014267
• Length: 1115
• Species: Anopheles gambiae
• Alignment Length: 998
• Identity: 195/998 - (19%)
• Similarity: 333/998 - (33%)
• Gaps: 333/998 - (33%)

  Fly    16 VTDGDR-NRDQPQKCASATLAKK--PVTP---PAAPPPTPSNRVVAPLTVPVIQLTPAQSDSPVK 74
            :||..| |..|.        |||  |.||   ....||...:.|:|..|   ..|:||.|::...
Mosquito    51 ITDKPRLNHSQN--------AKKNIPTTPNPWVIGGPPGGKDAVLAFRT---YALSPAASENGTD 104

  Fly    75 LARPATPKETAISVPDHSNKENQPARTPPPSKSCPLGAPTNYVARRTWITTERMNELRRKAQEAA 139
            |:...:|..|                  |.|.:.....||:.||..: .||.|:.||:...:.:.
Mosquito   105 LSPGGSPSAT------------------PSSDATSSSCPTDPVATGS-ATTARLAELKSATKSST 150

  Fly   140 KQNKIFTIRGCFNSVRNALLMRGWV---------------------------------------- 164
            ......::...||..|..   ||..
Mosquito   151 ATATHSSLPKNFNVQRKT---RGTAPSRSSTTTEDEEDEEDGEDGEEEDDDDEDEVDQDEETAAR 212

  Fly   165 ------EKLDVHR----------KVMPAGQMTYEDLTQRLPKRKAGETRRQYVQKCERNIMSRFL 213
                  |::|...          ....||..:.|:.:....|...||..|
Mosquito   213 DVDVQDEEIDEEEGEGNDDEEGGDETDAGTTSQEESSPAKGKPSVGEATR--------------- 262

  Fly   214 EHMPVDFLWTNRKEKCDYIDQAKNPGMTINKFHRAPFTSKEGLCSQLRDFHWFFEEGTAEMYFPR 278
                     ||:.:|......:.:..::     .|..:|.:|
Mosquito   263 ---------TNKPKKRQLESSSSSSSLS-----NASMSSVKG----------------------- 290

  Fly   279 CYNVWSPEELGEFIENFKL--TACVAFLRAMLCKYHKQGSD-----AVFSCSGKIPYSAIDFAYK 336
                .|.:|:...:...|.  :..:|.|...|....||..:     .......::|.:.::..||
Mosquito   291 ----GSGDEIDTEMSTSKSEPSLAMAALDKKLAAQRKQKEENKENQQTAPLKTEMPAAQLNICYK 351

  Fly   337 ------RLVEYI----------DSCQHNDIDF---------------------EDPPKIWEHDWD 364
                  ||:..|          ..|  ||.:.                     ...|:.:|
Mosquito   352 FINTETRLLRKILNAHGMGESGPEC--NDFNLLWTGIHLKPDILRNLAPYQRVNHFPRSYE---- 410

  Fly   365 AFLFQHQQLVNEDGRIQHDGGQRLEPMVKSCLSLVDKMKVHWPQYSLDGYQNM----------WI 419
              |.:..:|.....|:||..|.:...:|.....|        ||    .|:.:          ||
Mosquito   411 --LTRKDRLYKNIERMQHLRGYKHFDIVPQSFLL--------PQ----DYKELIAAHNKCRGPWI 461

  Fly   420 VKPANKCRGRGIILMDNLKKILGVVNLSIASKSRYVVQKYIERPLILFQTKFDIRQWFLITNTQP 484
            |||....|||||.::::..:        |:|..:.||.|||..||.:...|.|||.:..:|:..|
Mosquito   462 VKPVASSRGRGIFIVNSPDQ--------ISSFEQVVVAKYISDPLCIDGHKCDIRIYVAVTSFDP 518

  Fly   485 LVVWFYRESYLRFSSQEYSLSNH---HESVHLTNYAIQKKYTNGKRDKRLPSENMWDCYSFQAYL 546
            |:::.|.|..:|.::.:|..:..   :..:||.||:|.|.:|:..:......|::...::..|.|
Mosquito   519 LIIYIYEEGLVRLATVKYDRTAENLWNPCMHLCNYSINKYHTDYIKSSNAGEEDVGHKWTLSALL 583

  Fly   547 RQIGKYNMWLERIFPGMR----KAIVGC----MLASQENMDRRPNTFELFGADFMICENFYPWLI 603
            |.:.......|::...:.    |||..|    :.|.:..:....|.|||:|.|.:|.:...|||:
Mosquito   584 RHLRSQGCNTEQLMLAIEDLIIKAIFSCTQPIVSACRMFVPHIGNCFELYGFDILIDDMLKPWLL 648

  Fly   604 EINSSPDLGATTSVTARMCPQCLEDVVKVVIDRRTDP--KA-------ELGNFELAYRQVVPPTP 659
            |:|.||.||..|.:..::....|.|::.:|......|  ||       ::.|....||:|....
Mosquito   649 EVNLSPSLGCDTPLDTKVKASMLTDLLTMVGIPAISPLQKACYDSKGQKIRNLTTPYRRVNSAD- 712

  Fly   660 AYMGLNLFVKGKQVLQKANHGGGHGHYYYQQQRKERSLATSSVYRQRSAIIHPATSISRIHRA-- 722
                   ||......::....||.|     ||::.:......:....||:......|.|..|:
Mosquito   713 -------FVHTTSGRKEGAGTGGSG-----QQQQGKGDGGGKLQTTLSALTAEELKIVRFARSQY 765

  Fly   723 ------MPTFNATEYMEKY--MVEPLSSSRSSLCSQLPQKSPSAAPALTATPSGATSSYILKQAG 779
                  :..|..::.|.:|  :::|::...:|              |:|::.||
Mosquito   766 ERRGGFVRIFPTSDSMNRYGSLLDPITGIPTS--------------AITSSSSG----------- 805

  Fly   780 RSITQLLSATHKRNTGGSLSGEQVQSTALPP-------------KRQR--------SCGPRLSST 823
               |.|:...|..|       :.:.|...||             |.:|        :.||:.::.
Mosquito   806 ---TYLMIIPHNYN-------QMLHSQLFPPGSETENRIVHRIQKYERALESSLPITIGPKHAAP 860

  Fly   824 NPVESTEKKFKILIKNYSSNGNE 846
            ..|:.. |:.::.::....||:|
Mosquito   861 KCVDEA-KRLRLQVRKLIENGHE 882

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL3A	NP_609069.1	TTL	342..640	CDD:397308	84/349 (24%)
TTLL5	XP_313563.5	None