Protein Alignment TTLL3B and TTLL4

DIOPT Version :10

• Sequence 1: NP_609068.2
• Gene: TTLL3B / 33946
• FlyBaseID: FBgn0031853
• Length: 756
• Species: Drosophila melanogaster
• Sequence 2: XP_016860876.1
• Gene: TTLL4 / 9654
• HGNCID: 28976
• Length: 1226
• Species: Homo sapiens
• Alignment Length: 462
• Identity: 110/462 - (23%)
• Similarity: 192/462 - (41%)
• Gaps: 95/462 - (20%)

  Fly   240 GLVGCAEQERWYREDGVCGMSYPRFYRLGGNNLEERMAFIE-----------DYQQTQARSLLLY 293
            ||..|..::....|:|....|     .|...:..|.:|.|.           ...:...|..|:|
Human   518 GLEDCCSRDENEEEEGDSECS-----SLSAVSPSESVAMISRSCMEILTKPLSNHEKVVRPALIY 577

  Fly   294 -------------VREHQPAELISENGTIFSTTLDFALGKVKKMVRHAEHYSL----DD------ 335
                         .|:.:..:|..|...:....:......:.|......|:.:    ||
Human   578 SLFPNVPPTIYFGTRDERVEKLPWEQRKLLRWKMSTVTPNIVKQTIGRSHFKISKRNDDWLGCWG 642

  Fly   336 ARIKPPTPAEIVENQ-------TFMVQSTDVLKSNAKFKVSEKVMAEYARLAGLYLDQIESLRPD 393
            ..:|.|:...|.|:|       :|.:...|.|..|.     .::.:.:.:....:..|...|..|
Human   643 HHMKSPSFRSIREHQKLNHFPGSFQIGRKDRLWRNL-----SRMQSRFGKKEFSFFPQSFILPQD 702

  Fly   394 YR-----WD-GSRNLWILKPGYQSRGIGIVIRSSLDDILQWTSNNQNKKYIVQKYIERPLLIYRT 452
            .:     |: .||..||:||...:|||||.:      |.:|:...:.:..:||:|:.:|.||..:
Human   703 AKLLRKAWESSSRQKWIVKPPASARGIGIQV------IHKWSQLPKRRPLLVQRYLHKPYLISGS 761

  Fly   453 KFDIRQYMLLTITDTKVSIWTYRDCYLRFSSQEF--TMDDL-RESIHLTNNSVQKRYKN---KTN 511
            |||:|.|:.:|..| .:.|:.:.|..:||:|.::  :|..| .:.:||||.||.|  ||   :.|
Human   762 KFDLRIYVYVTSYD-PLRIYLFSDGLVRFASCKYSPSMKSLGNKFMHLTNYSVNK--KNAEYQAN 823

  Fly   512 RDSRLPKNNMWSLDQFKNYLRIMGA-PDGSWSKTYNGFKQNLVAVVMASLD-ETELLQ------- 567
            .|....:.:.|:|....|||...|. .|..|.|    .|..:|..:::|.. .|.||:
Human   824 ADEMACQGHKWALKALWNYLSQKGVNSDAIWEK----IKDVVVKTIISSEPYVTSLLKMYVRRPY 884

  Fly   568 NAFELYGCDFMLDEHYNPILIEINSTPDLSPSTEITARICPMVLKDCIRV----------VVDLP 622
            :..||:|.|.||||:..|.::|:|.:|.|..|:.:...|...:::|.:.:          ::..|
Human   885 SCHELFGFDIMLDENLKPWVLEVNISPSLHSSSPLDISIKGQMIRDLLNLAGFVLPNAEDIISSP 949

  Fly   623 KNPTAAT 629
            .:.:::|
Human   950 SSCSSST 956

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL3B	NP_609068.2	TTL	325..626	CDD:397308	92/348 (26%)
TTLL4	XP_016860876.1	TTL	654..946	CDD:397308	85/309 (28%)