Protein Alignment TTLL3B and Ttll7

DIOPT Version :10

• Sequence 1: NP_609068.2
• Gene: TTLL3B / 33946
• FlyBaseID: FBgn0031853
• Length: 756
• Species: Drosophila melanogaster
• Sequence 2: NP_001289886.1
• Gene: Ttll7 / 70892
• MGIID: 1918142
• Length: 912
• Species: Mus musculus
• Alignment Length: 644
• Identity: 132/644 - (20%)
• Similarity: 226/644 - (35%)
• Gaps: 207/644 - (32%)

  Fly   209 QGKGQRDLCAEVRPF----RNRVRRSQFLDFSTKVGLVGCAEQERWYREDGVCGMSYPRFYRLGG 269
            ||....||..|: |:    :.:||:.:      |.|::..          .|.|..: ...||
Mouse    11 QGSSPVDLGTEL-PYQCTMKRKVRKKK------KKGIITA----------NVAGTKF-EIVRL-- 55

  Fly   270 NNLEERMAFI----ED-----------YQQTQARSLLLYVR-EHQP--AELISENGTIFSTTLDF 316
              :.:.|.|:    ||           .||.:...|..|.| .|.|  .|:..:         ||
Mouse    56 --VIDEMGFMKTPDEDETSNLIWCDAAVQQEKITDLQNYQRINHFPGMGEICRK---------DF 109

  Fly   317 ALGKVKKMVRHAEHYSLDDARIKPPT---PAEIVENQTFMVQSTDVLKSNAKFKVSEKVMAEYAR 378
            ....:.||::....    |....|.|   |:|..:.|.::.:    ||...|.|.
Mouse   110 LARNMTKMIKSRPM----DYTFVPRTWIFPSEYTQFQNYVKE----LKKKRKQKT---------- 156

  Fly   379 LAGLYLDQIESLRPDYRWDGSRNLWILKPGYQSRGIGIVIRSSLDDILQWTSNNQNKKYIVQKYI 443
                                    :|:||...:.|.||.:..:.|.:      ......|||:||
Mouse   157 ------------------------FIVKPANGAMGHGISLIRNGDKV------PSQDHLIVQEYI 191

  Fly   444 ERPLLIYRTKFDIRQYMLLTITDTKVSIWTYRDCYLRFSSQEFTMDDLRES------IHLTNNSV 502
            |:|.|:...|||:|.|:|:|..| .:.|:.|.|..:|..::::...:  ||      :||||.||
Mouse   192 EKPFLMEGYKFDLRIYILVTSCD-PLKIFLYHDGLVRMGTEKYIPPN--ESNLTQLYMHLTNYSV 253

  Fly   503 QKRYKNKTNRDSRLPKNNMWSLDQFKNYLRIMGAPDGSWSKTYNGFKQNLVAVVMASLDETELLQ 567
            .| :..:..|:....|.:..|:..|..:|:   |.....:|.::...:.:|..::.:  |..:|.
Mouse   254 NK-HNERFERNETEDKGSKRSIKWFTEFLQ---ANQHDVTKFWSDISELVVKTLIVA--EPHVLH 312

  Fly   568 N---------------AFELYGCDFMLDEHYNPILIEINSTPDLSPSTEITARICPMVLKDCIRV 617
            .               .||:.|.|.:||....|.|:|||..|......:|...:...||.:.:::
Mouse   313 AYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKRGVLLNALKL 377

  Fly   618 V--------VDLPK------------NPTAATG-----------------------LFELAFEV- 638
            :        .:|.|            ||.....                       |.::..:|
Mouse   378 LNIRTSDKRKNLAKQKAEAQRRLYGQNPVRRLSPGSSDWEQQRHQLERRKEELKERLLQVRKQVS 442

  Fly   639 ----------NYSINKGADGKPL--ELNGKQMTLFE--------NMPRMRNSPRTRLLRKILNNV 683
                      ||......:.|.|  :..|.....|:        :..|..|:|..::..:.|.::
Mouse   443 QEEHENRHMGNYRRIYPPEDKALLEKYEGLLAVAFQTFLSGRAASFQREMNNPLKKMREEDLLDL 507

  Fly   684 KTSTTKKVEKVVEAPAKNVKNP--------TAKITKKKKLSASAGSSTAASAQPSTQNL 734
            ........||::....: |:.|        .|::|||:|...|:.||..:|:..|...|
Mouse   508 LEQCEIDDEKLMGKTGR-VRGPKPLCCMPECAEVTKKQKYYGSSDSSYDSSSSSSNSEL 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL3B	NP_609068.2	TTL	325..626	CDD:397308	74/344 (22%)
Ttll7	NP_001289886.1	TTL	91..376	CDD:397308	80/350 (23%)
		YhaN	<384..>474	CDD:443752	11/89 (12%)
		c-MTBD region. /evidence=ECO:0000250|UniProtKB:Q6ZT98	388..450		6/61 (10%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	547..570		6/19 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	658..688