Protein Alignment TTLL3B and Ttll8

DIOPT Version :10

• Sequence 1: NP_609068.2
• Gene: TTLL3B / 33946
• FlyBaseID: FBgn0031853
• Length: 756
• Species: Drosophila melanogaster
• Sequence 2: XP_056840443.1
• Gene: Ttll8 / 315214
• RGDID: 1306462
• Length: 927
• Species: Rattus norvegicus
• Alignment Length: 791
• Identity: 223/791 - (28%)
• Similarity: 346/791 - (43%)
• Gaps: 167/791 - (21%)

  Fly    42 QCSVQKPLTSLNNSTSLGSHFSNFGAL--------GGGSGSKTMGGSSSMGSNN----FSPDSIG 94
            ||..|....:|.|..:.|.......|.        .|..|.:.....:||.:..    .|..|.|
  Rat   101 QCIAQARPVALGNRKTPGRSGRRSAAAARAVGRVPAGAGGQRNQLREASMENGERKKLTSTLSDG 165

  Fly    95 NLLARVRASTPLPRTVTSSPTAPEAQKRQMRNVYRTRVIDAYRNRRIFTVYGNYHTVRRALMRRG 159
            :.....:....:|:.::|||      |.....:.|.....|.:.::||::||:|..:|..|.|:|
  Rat   166 DHKEENKLKQGIPQDLSSSP------KLDRYKIARQLTEKAIKEKKIFSIYGHYPVIRATLRRKG 224

  Fly   160 WLEK----LP--------ASRHAKLQSMSEDALLEHARRGNDYEAVVISKMINHFPAFFIWQGKG 212
            |:||    .|        ..:.|:.:...|.||    .|.:|...|:...:.|..| :.:|..|
  Rat   225 WVEKKFNFFPKPLQNVEGEDKSAETKENQEIAL----ERFDDIHDVMSRLVKNEIP-YLLWTIK- 283

  Fly   213 QRDL-------CAEVRPFRNRVRRSQFLDFSTKVGLVGCAEQERWYREDGVCGMSYPRFYRLGGN 270
             ||:       |.::.....:.     ..|:||:||........||.:... ...:||.|.|...
  Rat   284 -RDVVDYHSLTCDQMLNHYGKT-----ASFTTKIGLCLNMRSLPWYVQANP-NTFFPRCYGLCTE 341

  Fly   271 NLEERMAFIEDYQQTQARSLLLYVREHQPAELISENGTIFSTTLDFALGKVKKMVRHAEHYSLDD 335
            :  |:..|::|:::|.|.|:|.:|..||             ...:.|.||.||          ::
  Rat   342 S--EKQEFLDDFRRTVAASILKWVVHHQ-------------NYCNRAKGKSKK----------EE 381

  Fly   336 ARIKPPTPAEIVEN--------------------QTFMVQ-----------STDVLK-------- 361
            |:...|:|.:..:|                    |.::.|           |.:.|.
  Rat   382 AKNGDPSPKKDPDNPDLKLPSLSGQVVDTACKVCQAYLGQLEHEDIDLSDASAEALSEEEWNDLT 446

  Fly   362 --------SNAKFKVSEKVMAEYARLAGLYLDQIESLRPDYRWDGSRNLWILKPGYQSRGIGIVI 418
                    .||....|....|:...|    |.:|.|:.|....||.||:||:||..:|||..||.
  Rat   447 QQYYLLVHGNASITDSRSYFAQCQAL----LSKISSVNPQTEIDGIRNIWIIKPAAKSRGRDIVC 507

  Fly   419 RSSLDDIL-------QWTSNNQNKKYIVQKYIERPLLIYRTKFDIRQYMLLTITD-TKVSIWTYR 475
            ...:::||       |.|.:|   |::||||||.|:|||.|||||||:.|  :|| ..::||.|:
  Rat   508 MDRVENILDLVATDSQTTKDN---KWVVQKYIETPMLIYDTKFDIRQWFL--VTDWNPLTIWFYK 567

  Fly   476 DCYLRFSSQEFTMDDLRESIHLTNNSVQKRYKNKTNRDSRLPKNNMWSLDQFKNYLRIMGAPDGS 540
            :.|||||:|.|::|.|..:|||.|||:|:|.||...|...||.:|||:..:|:.||:..|. .|:
  Rat   568 ESYLRFSTQRFSLDKLDSAIHLCNNSIQRRLKNDKERSPLLPCHNMWTSTRFQEYLQKRGR-GGT 631

  Fly   541 W-SKTYNGFKQNLVAVVMASLDETELLQNAFELYGCDFMLDEHYNPILIEINSTPDLSPSTEITA 604
            | |..|...|:.:...:..:.|..|..:|:|||||.||:|...:.|.||||||:|.:.|||.:||
  Rat   632 WGSIIYPSMKRAVTNAMRVAQDHVEARKNSFELYGADFILGRDFKPWLIEINSSPTMHPSTPVTA 696

  Fly   605 RICPMVLKDCIRVVVDLPKNPTAATGLFELAFE---VNYSINKGAD----GKPLELNGKQMTLFE 662
            ::|..|.:|.|:||||...:.....|.|||.:.   |......|:|    |..::...|||....
  Rat   697 QLCAQVQEDTIKVVVDRKLDRNCDIGNFELLWRQPAVELPPFNGSDLCVEGISVKKAKKQMPPIA 761

  Fly   663 NM---PRMRNSPRTRLLRKILNNVKTSTTKKVEKVVEAPAKNVKNPTAKITKKKKLSASAGSSTA 724
            |:   ..:.::|           .|..:.:.:.:.|..|::....|..|..:.|.||.:..:...
  Rat   762 NLGFSDSLLDAP-----------TKARSARPLPETVIGPSRMTVRPDWKREEAKVLSNTWSAPVM 815

  Fly   725 AS-----AQPS 730
            |:     |:|:
  Rat   816 AAEVRGQAKPT 826

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL3B	NP_609068.2	TTL	325..626	CDD:397308	125/356 (35%)
Ttll8	XP_056840443.1	TTL	<489..711	CDD:397308	103/227 (45%)