Protein Alignment TTLL3B and TTLL6

DIOPT Version :9

• Sequence 1: NP_609068.2
• Gene: TTLL3B / 33946
• FlyBaseID: FBgn0031853
• Length: 756
• Species: Drosophila melanogaster
• Sequence 2: NP_001124390.1
• Gene: TTLL6 / 284076
• HGNCID: 26664
• Length: 891
• Species: Homo sapiens
• Alignment Length: 732
• Identity: 143/732 - (19%)
• Similarity: 250/732 - (34%)
• Gaps: 259/732 - (35%)

  Fly   239 VGLVGCAEQERWY--------REDGVCGMSYPRFYRLGGNNLEER-MAFIEDYQQTQARSLLLYV 294
            ||:.|.     ||        ||...|    |......|.|.||: .:..||.::|.|   |.:|
Human    31 VGIAGA-----WYFPRASSQAREMPQC----PTLESQEGENSEEKGDSSKEDPKETVA---LAFV 83

  Fly   295 REHQPAELISENGTIFSTTLDFALGKVKKMV------------RHAEHYSLDDARIKPPTPAEIV 347
            ||:..|    :||...:........|.|::|            |.|:.|...:..
Human    84 RENPGA----QNGLQNAQQQGKKKRKKKRLVINLSSCRYESVRRAAQQYGFREGG---------- 134

  Fly   348 ENQTFMVQSTDV---LKSNAKFKVSEKV-----MAEYAR---LAGLYLDQIESLRPDYR------ 395
            |:..:.:..||.   |:...:.|..:|:     |:|..|   ||......::....|:|
Human   135 EDDDWTLYWTDYSVSLERVMEMKSYQKINHFPGMSEICRKDLLARNMSRMLKMFPKDFRFFPRTW 199

  Fly   396 -----WDG----SRN----LWILKPGYQSRGIGIVIRSSLDDILQWTSNNQNKKYIVQKYIERPL 447
                 |..    ||:    .:|.||....:|.||.|..::.:|      ...:..|.|.||.:|.
Human   200 CLPADWGDLQTYSRSRKNKTYICKPDSGCQGKGIFITRTVKEI------KPGEDMICQLYISKPF 258

  Fly   448 LIYRTKFDIRQYMLLTITDTKVSIWTYRDCYLRFSSQEFT------MDDLRESIHLTNNSVQKRY 506
            :|...|||:|.|:|:|..| .:.|:.|.:...||::..::      :||:  .:||||.|:.|..
Human   259 IIDGFKFDLRIYVLVTSCD-PLRIFVYNEGLARFATTSYSRPCTDNLDDI--CMHLTNYSINKHS 320

  Fly   507 KNKTNRDSRLPKNNMWSLDQFKNYLRIMGAPDGSWS--KTYNGFKQNLVAVVMAS---------- 559
            .| .:||:.  ..:...|..|..||.     |.|::  :.:...:..::..::::
Human   321 SN-FSRDAH--SGSKRKLSTFSAYLE-----DHSYNVEQIWRDIEDVIIKTLISAHPIIRHNYHT 377

  Fly   560 -LDETELLQNAFELYGCDFMLDEHYNPILIEINSTPDLSPSTEITARICPMVLKDCIRVV----- 618
             .....|....||:.|.|.:||....|.|:|:|.:|..|..:.:...:...:|.|.:.::
Human   378 CFPNHTLNSACFEILGFDILLDHKLKPWLLEVNHSPSFSTDSRLDKEVKDGLLYDTLVLINLESC 442

  Fly   619 ----------------------------------VDLPKN---------------PTAATGLFEL 634
                                              |.|.|.               |:..:..:|.
Human   443 DKKKVLEEERQRGQFLQQCCSREMRIEEAKGFRAVQLKKTETYEKENCGGFRLIYPSLNSEKYEK 507

  Fly   635 AFEVNYSINKGA---------------------DGKP------LELNG---------KQMTLFEN 663
            .|:.|.|:.:..                     :.||      :|:.|         |.|..::.
Human   508 FFQDNNSLFQNTVASRAREEYARQLIQELRLKREKKPFQMKKKVEMQGESAGEQVRKKGMRGWQQ 572

  Fly   664 MPRMRNSPRTR-----------------LLRKILNNVKTSTTKKVEKVVEAPAKNVKNPTAKITK 711
            ..:.::...|:                 ||..:....|..|...:.:  |||.:...:...|:|.
Human   573 KQQQKDKAATQASKQYIQPLTLVSYTPDLLLSVRGERKNETDSSLNQ--EAPTEEASSVFPKLTS 635

  Fly   712 KKKLSA------------------------SAGSSTAASAQPSTQNL---------TTKLILNPA 743
            .|..|:                        .|.|::|.:....|.:|         ||:|.::|.
Human   636 AKPFSSLPDLRNINLSSSKLEPSKPNFSIKEAKSASAVNVFTGTVHLTSVETTPESTTQLSISPK 700

  Fly   744 TRENLAL----QYTAPK 756
            :...||:    :|:.|:
Human   701 SPPTLAVTASSEYSGPE 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL3B	NP_609068.2	TTL	325..626	CDD:281171	81/415 (20%)
TTLL6	NP_001124390.1	TTL	154..441	CDD:281171	70/303 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148123
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840