Protein Alignment TTLL3B and TTLL1

DIOPT Version :10

• Sequence 1: NP_609068.2
• Gene: TTLL3B / 33946
• FlyBaseID: FBgn0031853
• Length: 756
• Species: Drosophila melanogaster
• Sequence 2: NP_036395.1
• Gene: TTLL1 / 25809
• HGNCID: 1312
• Length: 423
• Species: Homo sapiens
• Alignment Length: 420
• Identity: 103/420 - (24%)
• Similarity: 176/420 - (41%)
• Gaps: 100/420 - (23%)

  Fly   309 IFSTTLDFALGKVKKMVRH-AEHYSLDDARIKPPTPAEIVENQTFMVQSTDVLKSNAKFKVSEKV 372
            :||....:.|.. .::|.| ..||.|                     ...|::..|.| :..:::
Human    47 VFSVEAGYRLSD-DQIVNHFPNHYEL---------------------TRKDLMVKNIK-RYRKEL 88

  Fly   373 MAEYARLAG-------LYLDQIE---SLRPDYRW------DGSRNLWILKPGYQSRGIGIVIRSS 421
            ..|.:.||.       ||||.:.   .|..||..      ....:.||:||..:::|.||.:.:.
Human    89 EKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINK 153

  Fly   422 LDDILQWT---------SNNQNKKYIVQKYIERPLLIYRTKFDIRQYMLLTITDTKVSIWTYRD- 476
            |..|.:|:         |.:..:.|::..||..||||...|||:|.|:|::         |||.
Human   154 LSQIKKWSRDSKTSSFVSQSNKEAYVISLYINNPLLIGGRKFDLRLYVLVS---------TYRPL 209

  Fly   477 -CYL------RFSSQEFT-----MDDLRESIHLTNNSVQKRYKNKTNRDSRLPKNNMWSLDQFKN 529
             ||:      ||.:.::|     :|::  .:||||.::||.     ..|........|::...:.
Human   210 RCYMYKLGFCRFCTVKYTPSTSELDNM--FVHLTNVAIQKH-----GEDYNHIHGGKWTVSNLRL 267

  Fly   530 YLRIMGAPDGSWSKTYNGFK----QNLVAVVMASLDETELLQNAFELYGCDFMLDEHYNPILIEI 590
            ||......:.: ||.::...    |:|.||.....::    ::.||.||.|.::|:...|.|||:
Human   268 YLESTRGKEVT-SKLFDEIHWIIVQSLKAVAPVMNND----KHCFECYGYDIIIDDKLKPWLIEV 327

  Fly   591 NSTPDLSPSTEITARICPMVLKDCIRVVV---DLP------KNPTAATGLFELAFEVNYSINKGA 646
            |::|.|:.||.....:...::.|.:.:.|   ::|      ..|....|.:|:.::...:...||
Human   328 NASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWNKSPPKEVLGNYEILYDEELAQGDGA 392

  Fly   647 DGKPLELNGKQ-MTLFENMPRMRNSPRTRL 675
            |   .||..:| .:|.....|.|:|.|..|
Human   393 D---RELRSRQGQSLGPRAGRSRDSGRAVL 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL3B	NP_609068.2	TTL	325..626	CDD:397308	85/352 (24%)
TTLL1	NP_036395.1	TTL	59..364	CDD:397308	85/347 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	391..423		12/32 (38%)