Protein Alignment TTLL3B and Ttll6

DIOPT Version :9

• Sequence 1: NP_609068.2
• Gene: TTLL3B / 33946
• FlyBaseID: FBgn0031853
• Length: 756
• Species: Drosophila melanogaster
• Sequence 2: NP_766387.2
• Gene: Ttll6 / 237930
• MGIID: 2683461
• Length: 822
• Species: Mus musculus
• Alignment Length: 594
• Identity: 121/594 - (20%)
• Similarity: 207/594 - (34%)
• Gaps: 176/594 - (29%)

  Fly   268 GGNNLEERMAFIEDYQQTQARSLLLYVREHQPAEL--ISENGTIFSTTLDFALGKVKKMV----- 325
            |....||  :..||.::.:....|.:|||:....|  ..::|.        ...|.|::|
Mouse    12 GAEEREE--SSTEDLEELKEFVTLAFVRENTQKRLQNAQQHGK--------KKRKKKRLVINLSN 66

  Fly   326 -------RHAEHYSLDDARIKPPTPAEIVENQTFMVQSTDV---LKSNAKFKVSEKV-----MAE 375
                   |.|:.|.|.:|.          :|..:.:..||.   |:...:.|..:|:     |:|
Mouse    67 CRYDSVRRAAQQYGLREAG----------DNDDWTLYWTDYSVSLERVMEMKSYQKINHFPGMSE 121

  Fly   376 YAR--LAGLYLDQIESLRP--------------------DYRWDGSRNLWILKPGYQSRGIGIVI 418
            ..|  |....:.::..|.|                    .|........:|.||....:|.||.|
Mouse   122 ICRKDLLARNMSRMLKLFPKDFHFFPRTWCLPADWGDLQTYSRTRKNKTYICKPDSGCQGRGIFI 186

  Fly   419 RSSLDDILQWTSNNQNKKYIVQKYIERPLLIYRTKFDIRQYMLLTITDTKVSIWTYRDCYLRFSS 483
            ..|:.:|      ...:..|.|.||.:|.:|...|||:|.|:|:|..| .:.::.|.:...||::
Mouse   187 TRSVKEI------KPGEDMICQLYISKPFIIDGFKFDLRVYVLVTSCD-PLRVFVYNEGLARFAT 244

  Fly   484 QEFT---MDDLRE-SIHLTNNSVQKRYKNKTNRDSRLPKNNMWSLDQFKNYLRIMGAPDGSWSKT 544
            ..::   :|:|.| .:||||.|:.|...|.........|.   .|..|.:|::..|.   ...:.
Mouse   245 TSYSHPNLDNLDEICMHLTNYSINKHSSNFVQDAFSGSKR---KLSTFNSYMKTHGY---DVEQI 303

  Fly   545 YNGFKQNLVAVVMAS-----------LDETELLQNAFELYGCDFMLDEHYNPILIEINSTPDLSP 598
            :.|.:..::..::::           .....|....||:.|.|.:||....|.|:|:|.:|..|.
Mouse   304 WRGIEDVIIKTLISAHPVIKHNYHTCFPSHTLNSACFEILGFDILLDRKLKPWLLEVNHSPSFST 368

  Fly   599 STEITARICPMVLKDCIRVVVD-------------------LPKNPTAATGLFEL---------- 634
            .:::...:...:|.|.: |:::                   |.:.|.....|.|:
Mouse   369 DSKLDKEVKDSLLYDAL-VLINLGNCDKKKVLEEERQRGRFLQQCPNREIRLEEVKGFQAMRLQK 432

  Fly   635 ----------AFEVNYSINKGADGKPLELNGK----QMTLFENMPRMRNSPRTRLLRKILNNVKT 685
                      .|.:.|      .|..||...|    ..:||:|....|  .|....|:::..::.
Mouse   433 TEEYEKKNCGGFRLIY------PGLNLEKYDKFFQDNSSLFQNTVASR--ARELYARQLIQELRQ 489

  Fly   686 STTKKVEKVVEAPAKNVKNPTAKITKKKKLSASAGSSTAASA------------QPSTQNLTT-- 736
            ...|||                 ..||.:...:.|.|....|            ||..:.:.|
Mouse   490 KQEKKV-----------------FLKKARKEETQGESAGEQARDKVVRLQRQRQQPKCKTVATCP 537

  Fly   737 -KLILNPAT 744
             |..|:|.|
Mouse   538 PKQSLHPVT 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL3B	NP_609068.2	TTL	325..626	CDD:281171	78/376 (21%)
Ttll6	NP_766387.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24		4/13 (31%)
		TTL	105..385	CDD:281171	66/292 (23%)
		c-MTBD region. /evidence=ECO:0000250|UniProtKB:Q8N841	371..450		9/85 (11%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	736..772
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	791..822

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838212
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840