Protein Alignment TTLL3B and Ttll2

DIOPT Version :10

• Sequence 1: NP_609068.2
• Gene: TTLL3B / 33946
• FlyBaseID: FBgn0031853
• Length: 756
• Species: Drosophila melanogaster
• Sequence 2: XP_011244473.1
• Gene: Ttll2 / 100216474
• MGIID: 3644030
• Length: 551
• Species: Mus musculus
• Alignment Length: 548
• Identity: 129/548 - (23%)
• Similarity: 214/548 - (39%)
• Gaps: 119/548 - (21%)

  Fly   267 LGGNNLEERMAF-IEDYQQ-TQARSLLLYVREHQPAELISENGTIFSTTLDFALGKVKKMVRHAE 329
            |.|::::|.... .||..| ...:.|:..|.|..|       |.:.|..|:....|..:..:..|
Mouse    30 LEGHSVQESKPLKTEDEPQGAPLKPLVFRVDESTP-------GLVQSVLLERGWDKFDEQRQDVE 87

  Fly   330 HYSL----------DDARIKPPTPAEIVENQTFMVQSTDVLKSNAKFK------------VSEKV 372
            .::|          :...:||..........|.:.:...:.|..|:.:            ::..:
Mouse    88 DWNLYWRSSSFRRAEYVNVKPWQRLNHHPGMTNLTRKDCLAKHLARMRSRYGESLYEFTPLTFIM 152

  Fly   373 MAEYARLAGLYLDQIESL--RPDYRWDGSRNLWILKPGYQSRGIGIVIRSSLDDILQWTSNNQNK 435
            ..:|.:....|..:.:.|  :|.|        ||.||...|||.||:|.|.:.|::      ...
Mouse   153 PTDYTKFVAKYFKEKQDLGTKPSY--------WICKPAELSRGRGIIIFSDIRDLM------FKG 203

  Fly   436 KYIVQKYIERPLLIYRTKFDIRQYMLLTITDTK-VSIWTYRDCYLRFSSQEFTMDDLRESI-HLT 498
            .|:|||||..|||:.|.|.|:|.|  :.||..| ::|:.|::..:||::::|.:.:|.:.. |||
Mouse   204 TYVVQKYICNPLLVGRYKCDLRIY--VCITGFKPLTIYMYQEGLVRFATEKFDLRNLEDYYSHLT 266

  Fly   499 NNSVQKRYKNKTNRDSRLPKNNMWSLDQFKNYLRIMGAPDGSWSKTYNGFKQNL----VAVVMAS 559
            |:|:.|...:.......:.:...|:|.:|.:|||       :|.......:|.:    :..|:|.
Mouse   267 NSSINKLGASYQKIKEVVGQGCKWTLSRFFSYLR-------NWDVDDLLLRQKISHMVILTVLAM 324

  Fly   560 LDETELLQNAFELYGCDFMLDEHYNPILIEINSTP----DLSPSTEITARICPMVL--------- 611
            .....:..|.|||:|.|.::|::..|.|:|:|..|    |.|....:...:...|:
Mouse   325 APSVPVTYNCFELFGFDILIDDNLKPWLLEVNYNPALTLDCSTDESVKRSLVHDVIELLYLNGLR 389

  Fly   612 ---KDCIRV-----VVDLPK----------NPTAATGLFELAFEVNYSINKGADGKPLELN---- 654
               |.|.|.     ||.|.:          |.::...|.|        ...|:...|...|
Mouse   390 SEEKKCGRTSPGNSVVSLARSHHHEFCATPNSSSYASLIE--------FTTGSKSDPAVQNICPK 446

  Fly   655 -GKQMTLFENMPRMRNSPRTRLLRKILNNVKTSTTKKVEKVVEAPAKNVKNPTAKITKKKKLSAS 718
             .:...|.|.|.|     |.|||.|     :.:.:|...|....|.|.| .|.|..::..|:...
Mouse   447 HTRTSQLREMMSR-----RDRLLTK-----EAAKSKPRHKAWHLPRKMV-FPYASQSQPHKMKGP 500

  Fly   719 AGSSTAASAQPSTQ--NLTTKLILNPAT 744
            ||....|.:.|:..  |.......|.||
Mouse   501 AGDLPEAGSTPNDHAGNFVLIFPFNKAT 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL3B	NP_609068.2	TTL	325..626	CDD:397308	85/361 (24%)
Ttll2	XP_011244473.1	TTL	108..381	CDD:397308	75/295 (25%)