Protein Alignment homer and Homer2

DIOPT Version :9

• Sequence 1: NP_001036341.2
• Gene: homer / 33944
• FlyBaseID: FBgn0025777
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_036113.1
• Gene: Homer2 / 26557
• MGIID: 1347354
• Length: 354
• Species: Mus musculus
• Alignment Length: 395
• Identity: 163/395 - (41%)
• Similarity: 215/395 - (54%)
• Gaps: 102/395 - (25%)

  Fly     1 MGEQPIFTCQAHVFHIDPKTKRTWITASMKAVNVSFFYDSSRNLYRIISVEGTKAVINSTITPNM 65
            ||||||||.:||||.|||.||:.|:.||.:||.||:|||.:||.||||||:|.|.:|||||||||
Mouse     1 MGEQPIFTTRAHVFQIDPSTKKNWVPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINSTITPNM 65

  Fly    66 TFTQTSQKFGQWSDVRANTVYGLGFASEAELTKFVEKFQEVKEATKNAMKSANGSNAVTPTTSAN 130
            |||:||||||||:|.|||||:||||:||.:||||.||||||:||.:.|...:....    .||:|
Mouse    66 TFTKTSQKFGQWADSRANTVFGLGFSSELQLTKFAEKFQEVREAARLARDKSQEKT----ETSSN 126

  Fly   131 TSPISGRAVGSMQNDNTAIDPHTVEPPNMSNTNTQNANPDSPSHKLLNTSDVKADIGSATPSPQP 195
            .|..||                 .|.|  |:|...:.|         .|.|.||.
Mouse   127 HSQESG-----------------CETP--SSTQASSVN---------GTDDEKAS---------- 153

  Fly   196 TSGVTGGGGVTISSGGSIVGMHTGPGAGATAEQQLKYENERLKMALAQSCANAKKWEIELATLKN 260
                                 |..|     |:..||.||::||:||.||.||.||||:||.||:.
Mouse   154 ---------------------HASP-----ADTHLKSENDKLKIALTQSAANVKKWEMELQTLRE 192

  Fly   261 NNIRLTSALQESTANVDEWKRQLHTYKEENIRLKRDMEQL---CVGGGVVAAAGGGATEDELRRE 322
            :|.|||:|||||.|:|::||||....::||.||:..:|:|   |               .|:.||
Mouse   193 SNARLTTALQESAASVEQWKRQFSICRDENDRLRSKIEELEEQC---------------SEINRE 242

  Fly   323 V---ATLKARTEQLQKELMQQELELKSANISLREKSN--DQTLAKLSEVNGVFAKHLSELYGVQK 382
            .   ..||.|.|:|:.|:..:|:|||    .||::|.  .|.:::...|:       .:|...::
Mouse   243 KEKNTQLKRRIEELESEVRDKEMELK----DLRKQSEIIPQLMSECEYVS-------EKLEAAER 296

  Fly   383 DMESL 387
            |.::|
Mouse   297 DNQNL 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
homer	NP_001036341.2	EVH1_Homer_Vesl	3..111	CDD:269917	79/107 (74%)
Homer2	NP_036113.1	EVH1_Homer_Vesl	3..111	CDD:269917	79/107 (74%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	110..166		21/123 (17%)
		SMC_prok_B	<167..>342	CDD:274008	59/161 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850704
Domainoid	1	1.000	164	1.000	Domainoid score	I3921
eggNOG	1	0.900	-	-		E1_28ISB
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3560
Inparanoid	1	1.050	242	1.000	Inparanoid score	I3302
Isobase	1	0.950	-	0	Normalized mean entropy	S3324
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004784
OrthoInspector	1	1.000	-	-		otm44098
orthoMCL	1	0.900	-	-		OOG6_106337
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R7014
SonicParanoid	1	1.000	-	-		X1808
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.630