Protein Alignment homer and Homer1

DIOPT Version :9

• Sequence 1: NP_001036341.2
• Gene: homer / 33944
• FlyBaseID: FBgn0025777
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_036013945.1
• Gene: Homer1 / 26556
• MGIID: 1347345
• Length: 382
• Species: Mus musculus
• Alignment Length: 421
• Identity: 160/421 - (38%)
• Similarity: 225/421 - (53%)
• Gaps: 92/421 - (21%)

  Fly     3 EQPIFTCQAHVFHIDPKTKRTWITASMKAVNVSFFYDSSRNLYRIISVEGTKAVINSTITPNMTF 67
            |||||:.:||||.|||.||:.|:..|..||.||:||||:||:|||||::|:||:|||||||||||
Mouse    19 EQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINSTITPNMTF 83

  Fly    68 TQTSQKFGQWSDVRANTVYGLGFASEAELTKFVEKFQEVKEATKNAMKSANGSNAVTPTTSANT- 131
            |:||||||||:|.||||||||||:||..|:||.|||||.|||.:.|.:.:.....:|.|.|..:
Mouse    84 TKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEKMELTSTPSQESA 148

  Fly   132 -----SPISGRAVGSMQNDNTAIDPHTVEPPNMSNTNTQNANPDS-PSHKLLNTSDVKADIGSAT 190
                 ||::..::....::.|         |::    |||:.|.: |:.             :|.
Mouse   149 GGDLQSPLTPESINGTDDERT---------PDV----TQNSEPRAEPTQ-------------NAL 187

  Fly   191 PSPQPTSGVTGGGGVTISSGGSIVGMHTGPGAGATAEQQLKYENERLKMALAQSCANAKKWEIEL 255
            |.|.             |:|                        :|.:.....|.|.:|.||.||
Mouse   188 PFPH-------------SAG------------------------DRTQALSHASSAISKHWEAEL 215

  Fly   256 ATLKNNNIRLTSALQESTANVDEWKRQLHTYKEENIRL-KRDMEQLCVGGGVVAAAGGGATEDEL 319
            ||||.||.:||:||.||||||.:||:||..|:||..|| ||..|..||.....|.   .:.:.||
Mouse   216 ATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQANAV---HSHKTEL 277

  Fly   320 RREV----ATLKARTEQLQKELMQQEL----ELKSANISLREK------SNDQTLAKLSEVNGVF 370
            .:.|    .|||.:.|::::  ::||:    ||:....||.:|      .|.....:||::....
Mouse   278 NQTVQELEETLKVKEEEIER--LKQEIDNARELQEQRDSLTQKLQEVEIRNKDLEGQLSDLEQRL 340

  Fly   371 AKHLSELYGVQKDMESLIQI--AKCTXDTEL 399
            .|..:|....:.::::|::|  .|.. .|||
Mouse   341 EKSQNEQEAFRSNLKTLLEILDGKIFELTEL 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
homer	NP_001036341.2	EVH1_Homer_Vesl	3..111	CDD:269917	78/107 (73%)
Homer1	XP_036013945.1	EVH1_Homer_Vesl	19..127	CDD:269917	78/107 (73%)
		Smc	<203..>380	CDD:224117	63/174 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	164	1.000	Domainoid score	I3921
eggNOG	1	0.900	-	-		E1_28ISB
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	242	1.000	Inparanoid score	I3302
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1251658at2759
OrthoFinder	1	1.000	-	-		FOG0004784
OrthoInspector	1	1.000	-	-		otm44098
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10918
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R7014
SonicParanoid	1	1.000	-	-		X1808
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.960