Protein Alignment Aatf and Aatf

DIOPT Version :9

• Sequence 1: NP_609066.1
• Gene: Aatf / 33943
• FlyBaseID: FBgn0031851
• Length: 488
• Species: Drosophila melanogaster
• Sequence 2: NP_062790.1
• Gene: Aatf / 56321
• MGIID: 1929608
• Length: 526
• Species: Mus musculus
• Alignment Length: 546
• Identity: 169/546 - (30%)
• Similarity: 261/546 - (47%)
• Gaps: 102/546 - (18%)

  Fly     9 PQTVAEKVSKLL-AHPNESDSAEDSDFDVATGPRLVD-FEEEEYDLPDARSTDFRKRNVKLLSEQ 71
            ||.:|.::.:|| ..|.|:|  .::|.:.||..|::| |:|.|.:..|...:..||.....|.:.
Mouse     4 PQPLALQLEQLLNPRPREAD--PEADPEEATRARVIDRFDEGEEEKDDLAVSSIRKLAPVSLLDT 66

  Fly    72 SDRYKGKISSRKELDDDEDKDDEQEVSYEESDEDDENLTNFKQKLNAGGAEDSEEETAAGHSESG 136
            ..||.||.:|||..     |:|..|.:...|.:::.:        :.||:||.:.| ..|..|.
Mouse    67 DKRYSGKTTSRKAW-----KEDHWEQALPSSSDNEAS--------DEGGSEDGDSE-GLGLEEI- 116

  Fly   137 EESEEIESNLTDFKKKFEAGDFKYDDDEEEDDDSE-------EEDHSQESEGDD--DDSEDDEAE 192
              ||:::.:|.|.|...|.|        .||.|||       .||..::.||:|  |..||..:|
Mouse   117 --SEDVDEDLEDNKISDEGG--------SEDGDSEGLGLEEFSEDVEEDLEGEDEEDREEDRNSE 171

  Fly   193 DDAIKPSDVMSKTNHQAEIQKGLAVQNQLRIWERLLELRINTQKFTSKANQLPAPETLTKLASE- 256
            ||.:..:  .|......|::||.||:||:.:|::|||.||..||.....||||.|:.......:
Mouse   172 DDGVVAA--FSSVKVSEEVEKGRAVKNQIALWDQLLEGRIKLQKALLTTNQLPQPDVFPVFKDKG 234

  Fly   257 SDELQSVLNEAQERSSKLLQQLLSLQSALHQQYSEMKKSVKRKQPTEDS---------------- 305
            ..|..|.|..:.:....||:.|:.||..|..||.:.:..|...:|..:|
Mouse   235 GPEFASALKNSHKALKALLRSLVDLQEELLFQYPDTRHIVNGAKPNTESEEISSEDDELVGEKKK 299

  Fly   306 ---GPAVKK-----FGSVLQSNFQQMIGYRNEVLLKWDDRTKL----LTPGAGVKRKSLQEDYDI 358
               .|..:|     :.|.:...|.....|||..|.||.|:|||    |..|.|...:|      |
Mouse   300 QRKAPPKRKLEMEDYPSFMAKRFADFTIYRNHTLQKWHDKTKLASGKLGKGFGAFERS------I 358

  Fly   359 IKKIGSALANREALVEKSQTPKNSQAEQQENTPVQRL-------------------------KHI 398
            :.:|...:.::|.|:.::||.:::.....:..||...                         :.|
Mouse   359 LTQIDHIMMDKERLLRRTQTKRSAYRVLGKPEPVPEPVAETLPGEPETLPQGPANAHLRDLDEEI 423

  Fly   399 YDDSDFYHQQLRELIEYKASTSSNMSEIT--KQFVELQKLRQKMKKKVDTRASKGRKLRYVVHNK 461
            :||.|||||.||||||.|.|:.....::.  :|::.:||||.|::||||.:||||||||:.|.:|
Mouse   424 FDDDDFYHQLLRELIERKTSSLDPNDQVAMGRQWLAIQKLRSKIRKKVDRKASKGRKLRFHVLSK 488

  Fly   462 LINFMAPNESSDWTDASKSELYKSLF 487
            |::||||.:.:..:|.:::||::|||
Mouse   489 LLSFMAPIDHTAMSDDARTELFRSLF 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aatf	NP_609066.1	AATF-Che1	211..337	CDD:290078	43/150 (29%)
		TRAUB	405..487	CDD:285388	40/83 (48%)
Aatf	NP_062790.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	13..51		14/39 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..175		33/118 (28%)
		AATF-Che1	188..339	CDD:290078	52/179 (29%)
		Binds POLR2J. /evidence=ECO:0000250	240..282		11/42 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	274..307		10/56 (18%)
		Binds RB1. /evidence=ECO:0000250	283..338		20/82 (24%)
		Binds RB1 and SP1. /evidence=ECO:0000250	339..438		33/125 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	388..410		13/46 (28%)
		TRAUB	430..514	CDD:285388	29/53 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	83	1.000	Domainoid score	I8368
eggNOG	1	0.900	-	-		E1_KOG2773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	210	1.000	Inparanoid score	I3658
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54578
OrthoDB	1	1.010	-	-		D428754at33208
OrthoFinder	1	1.000	-	-		FOG0005185
OrthoInspector	1	1.000	-	-		oto92688
orthoMCL	1	0.900	-	-		OOG6_102684
Panther	1	1.100	-	-	LDO	PTHR15565
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R139
SonicParanoid	1	1.000	-	-		X4800
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.870