DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Aatf and SPAC664.08c

DIOPT Version :9

Sequence 1:	NP_609066.1	Gene:	Aatf / 33943	FlyBaseID:	FBgn0031851	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_593456.1	Gene:	SPAC664.08c / 2543540	PomBaseID:	SPAC664.08c	Length:	452	Species:	Schizosaccharomyces pombe

Alignment Length:	510	Identity:	136/510 - (26%)
Similarity:	224/510 - (43%)	Gaps:	140/510 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 EKVSKLLAHPNESD--SAEDSDFDVATGPRLVDFEEEEYDLPDARSTDFRKRNV-----KLLSEQ 71
            |....|...|.|.|  :.||:..|      ..|..|||.|      |..|:..|     ||.|:|
pombe     9 ELAGMLNPQPQERDPEALEDAFSD------REDSSEEEND------TLGREHYVDVSESKLRSKQ 61

  Fly    72 S----DRYKGKISSRKELDDDEDKDDEQEVSYEESDEDDENLTNFKQKLNAGGAEDSEEETAAGH 132
            :    .::||:.:||:||                              ||:|..          :
pombe    62 APQLDPKFKGRKTSRQEL------------------------------LNSGSL----------N 86

  Fly   133 SESGEESEEIESNLTDFKKKFEAGDFKYDDDEEEDDDSEEEDH-----------SQESEGDDDDS 186
            |:|...|||                   :|.||:::|:..|||           |:|:|.||..|
pombe    87 SQSSSPSEE-------------------EDSEEDENDAVSEDHENFSSSEASSISEENEDDDQSS 132

  Fly   187 EDDEAEDDAIKP--------SDVMSKTNHQAEIQKGLAVQNQLRIWERLLELRINTQKFTSKANQ 243
            ...|.:.|.:|.        ||.: :|:...:::||||::.|:|.::.:|:.||..||..|
pombe   133 AIPEKDMDRLKKIINGEKKLSDQI-RTSALEDMKKGLALKEQMRFYDNVLDTRIRLQKGCS---- 192

  Fly   244 LPAPETLTKLASESDELQSVLNEAQERSSKLLQQLLSLQSAL--HQQYSEMKKSVKRKQPTEDSG 306
                    :|.|.|::||....||::.....:|..|.|:..|  ......:....|||:     .
pombe   193 --------QLLSSSNQLQGDKVEARDGLVSFIQHTLQLRKNLLIDSGVEILDSRSKRKE-----N 244

  Fly   307 PAVKKFGSVLQSNFQQMIG-YRNEVLLKWDDRTKLLTPGAGVKRKSLQEDYDIIKKIGSALANRE 370
            |...:..::..:|....:. ::|:.|.||.:|.:.: .|.....|....:..|:::|.:::.|::
pombe   245 PVSLEEIALEMNNLDDSLNEWKNDTLTKWHNRVQAV-QGISQSNKFKALNQSIVQQIENSMINKK 308

  Fly   371 ALVEKSQ----TPKNSQAEQQENTPVQRLKHIYDDSDFYHQQLRELIEYKASTSSNMSEITKQFV 431
            .|||:::    .|.|.....:          ||:|:|||...|::.|..:.:.|:.  :.|.:::
pombe   309 DLVERTRIDYSDPNNKTFNPE----------IYNDTDFYQSLLKDFINSRMADSTR--DGTVRWM 361

  Fly   432 ELQKLRQKMKKKVDTRASKGRKLRYVVHNKLINFMAPNESSDWTDASKSELYKSL 486
            ..:|.:|| |:.|||:||||||:||.||:||.|||||.|.:.|.|....:|:.||
pombe   362 ATKKQKQK-KENVDTKASKGRKIRYHVHDKLQNFMAPIEVTVWPDEQTEDLFSSL 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Aatf	NP_609066.1	AATF-Che1	211..337	CDD:290078	32/128 (25%)
Aatf	NP_609066.1	TRAUB	405..487	CDD:285388	35/82 (43%)
SPAC664.08c	NP_593456.1	AATF-Che1	164..276	CDD:290078	32/128 (25%)
SPAC664.08c	NP_593456.1	TRAUB	337..416	CDD:285388	35/82 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	64	1.000	Domainoid score	I2876
eggNOG	1	0.900	-	-		E1_KOG2773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	129	1.000	Inparanoid score	I1432
OMA	1	1.010	-	-		QHG54578
OrthoFinder	1	1.000	-	-		FOG0005185
OrthoInspector	1	1.000	-	-		oto100823
orthoMCL	1	0.900	-	-		OOG6_102684
Panther	1	1.100	-	-	LDO	PTHR15565
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R139
SonicParanoid	1	1.000	-	-		X4800
TreeFam	0	0.000	Not matched by this tool.
	11	10.900