Protein Alignment AkhR and Oxtr

DIOPT Version :10

• Sequence 1: NP_995639.1
• Gene: AkhR / 33942
• FlyBaseID: FBgn0025595
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_001074616.1
• Gene: Oxtr / 18430
• MGIID: 109147
• Length: 388
• Species: Mus musculus
• Alignment Length: 356
• Identity: 105/356 - (29%)
• Similarity: 174/356 - (48%)
• Gaps: 58/356 - (16%)

  Fly    39 RLSITVYSILFVISTIGNSTVLYLLTKRRLRGPLRIDIMLMHLAIADLMVTLLLMPMEIVWAWTV 103
            |:.:.|..::..::..||:.||..|...|.:.. |:...:.||:||||:|.:..:..:::|..|.
Mouse    40 RVEVAVLCLILFLALSGNACVLLALRTTRHKHS-RLFFFMKHLSIADLVVAVFQVLPQLLWDITF 103

  Fly   104 QWLSTDLMCRLMSFFRVFGLYLSSYVMVCISLDRYFAILKPLKRSYNR--GRIMLACAWLGSVVC 166
            ::...||:|||:.:.:|.|::.|:|:::.:||||..||.:|| ||..|  .|:.:...|||.:|.
Mouse   104 RFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPL-RSLRRRTDRLAVLATWLGCLVA 167

  Fly   167 SIPQAFLFHLEEHPAVTGYFQCVIFNSFRSDFDEKLYQAASMCSMYAFPLIMFIYCYGAIYLEIY 231
            |:||..:|.|.|  ...|.|.|  :..|...:..|.|......::|..|:|:...|||.|..:|:
Mouse   168 SVPQVHIFSLRE--VADGVFDC--WAVFIQPWGPKAYVTWITLAVYIVPVIVLAACYGLISFKIW 228

  Fly   232 RKSQRVLKDVIAERFRRSND----------------DVLSRAKKRTLKMTITIVIVFIICWTPYY 280
            :..:  ||...|......:|                .::|:||.||:|||..||:.||:||||::
Mouse   229 QNLR--LKTAAAAAAAEGSDAAGGAGRAALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFF 291

  Fly   281 TISMWYWLDKHSAGKINPLLRKALFI----FASTNSCMNPLVYGLYNIRGR-------------- 327
            .:.||      |...:|.....:.||    .||.|||.||.:|.|:.  |.
Mouse   292 FVQMW------SVWDVNAPKEASAFIIAMLLASLNSCCNPWIYMLFT--GHLFHELVQRFLCCSA 348

  Fly   328 --MNNNNPSVNNRHTSLSNRLDSSNQLMQKQ 356
              :..:.|.    .||:|.:.:||..::.::
Mouse   349 RYLKGSRPG----ETSISKKSNSSTFVLSRR 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AkhR	NP_995639.1	7tmA_AKHR	39..328	CDD:320504	99/326 (30%)
		TM helix 1	40..66	CDD:320504	6/25 (24%)
		TM helix 2	74..101	CDD:320504	8/26 (31%)
		TM helix 3	112..142	CDD:320504	12/29 (41%)
		TM helix 4	151..172	CDD:320504	9/22 (41%)
		TM helix 5	200..229	CDD:320504	9/28 (32%)
		TM helix 6	256..286	CDD:320504	16/29 (55%)
		TM helix 7	298..323	CDD:320504	11/28 (39%)
Oxtr	NP_001074616.1	7tmA_OT_R	40..339	CDD:320509	99/314 (32%)
		TM helix 1	41..67	CDD:320509	6/25 (24%)
		TM helix 2	74..101	CDD:320509	8/26 (31%)
		TM helix 3	112..142	CDD:320509	12/29 (41%)
		TM helix 4	152..173	CDD:320509	8/20 (40%)
		TM helix 5	197..226	CDD:320509	9/28 (32%)
		TM helix 6	267..297	CDD:320509	17/35 (49%)
		TM helix 7	307..332	CDD:320509	11/24 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	354..388		6/26 (23%)