DRSC/TRiP Functional Genomics Resources

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Protein Alignment AkhR and gnrr-4

DIOPT Version :9

Sequence 1:NP_995639.1 Gene:AkhR / 33942 FlyBaseID:FBgn0025595 Length:455 Species:Drosophila melanogaster
Sequence 2:NP_741799.1 Gene:gnrr-4 / 180841 WormBaseID:WBGene00016570 Length:514 Species:Caenorhabditis elegans


Alignment Length:428 Identity:105/428 - (24%)
Similarity:166/428 - (38%) Gaps:84/428 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 TKDMVFNDGHRLSITVYSILFVISTIG-NSTVLYLLTKRRLRGPL----RIDIMLMHLAIADLMV 88
            |:.:..:..:.|.:.:|.|.|.:.... ..||:.|...|..|..|    |:....:.|::||.:|
 Worm     9 TQRVELSFSYTLELWMYGIAFCVGLPAFIFTVVRLARSRSSRQHLVLAARLFSYKISLSVADCIV 73

  Fly    89 TLLLMPMEIVWAWTVQWLSTDLMCRLMSFFRVFGLYLSSYVMVCISLDRYFAILKP-------LK 146
            ..:..|.:..|..:..|...|:.|||..|...||.:|::.:.|.::.||.....|.       .|
 Worm    74 LFIYAPTQFAWIHSYWWFGGDIGCRLFKFISTFGFHLTANMQVLVAADRLLITAKMNRVTRNIKK 138

  Fly   147 RSYNRGRIMLACAWLGSVVCSIPQAFLFHLEEHPAVTGYFQCV-IFNSFRSDFDEKLYQAASMCS 210
            |.||. |:.||.||:.:::|:.||..||..:..|  .||.||: |:...|.||    |....:..
 Worm   139 RQYNT-RLSLAAAWILALICAGPQLILFRQKTTP--QGYPQCISIWTEHRVDF----YDRLELLE 196

  Fly   211 MYAFPLIMFIYCYGAIYLEIYRKSQ---------RVLKD-------VIAERFRRSNDDVLSRAKK 259
            .||:           :..|:..||.         |..|:       ...|....:|.:.|     
 Worm   197 QYAY-----------MQHELANKSPIYFFENGTLRYAKEDFPSEPGFTLEELHTNNRNWL----- 245

  Fly   260 RTLKMTITIVIVFIICWTPY------YTISMWYWLDKHSAGKINPLLRKALFIFASTNSCMNPLV 318
             .|:....::.:..||..||      ||:.: |.|...|.|:           |.|.:..:..:.
 Worm   246 -YLERLYNVLHLATICVIPYAMELICYTLIL-YILKGASKGR-----------FVSLSDIVKDIF 297

  Fly   319 YGLYNIRGRMNNNNPSVNNRHTSLSNRLDSSNQLMQKQLTNNSLLNGRGQVM----AAAVSATTK 379
            ......|...:....:|.....:|..|:.|..:.:|     |....|:...|    ||:|....:
 Worm   298 CCCKRARQHESPIESNVTQESDNLMARVPSKTKRLQ-----NIAPEGKSCDMERRRAASVDVPMR 357

  Fly   380 LANVVSLKGTANGNGSAAAAGTVPITP----PLTVTIA 413
            :.|..||....:.||||.||....:||    |.|.|.|
 Worm   358 IKNSSSLTVCIDENGSATAATRPEVTPQEQEPETRTQA 395

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AkhRNP_995639.1 7tm_1 55..319 CDD:278431 73/298 (24%)
gnrr-4NP_741799.1 7tm_GPCRs 25..>179 CDD:391938 48/156 (31%)
TM helix 1 25..46 CDD:341315 6/20 (30%)
TM helix 2 59..86 CDD:341315 6/26 (23%)
TM helix 3 97..126 CDD:341315 10/28 (36%)
TM helix 4 139..163 CDD:341315 11/24 (46%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D368588at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.920

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