Protein Alignment AkhR and LOC1281610

DIOPT Version :10

• Sequence 1: NP_995639.1
• Gene: AkhR / 33942
• FlyBaseID: FBgn0025595
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: XP_061505639.1
• Gene: LOC1281610 / 1281610
• VectorBaseID: AGAMI1_011925
• Length: 614
• Species: Anopheles gambiae
• Alignment Length: 405
• Identity: 112/405 - (27%)
• Similarity: 203/405 - (50%)
• Gaps: 61/405 - (15%)

  Fly    40 LSITVYSILFVISTIGNSTVLYLLTK-RRLRGPLR-----IDIMLMHLAIADLMVTLLLMPMEIV 98
            :.:.|.|.:.::|.:||...::.:.| |:.|...|     |..::.||:|||::||...:..|..
Mosquito   179 IRVIVLSAMAIVSLLGNVATMWNIQKNRKSRRVTRHNWSAIYSLIFHLSIADVLVTGFCLIGEAA 243

  Fly    99 WAWTVQWLSTDLMCRLMSFFRVFGLYLSSYVMVCISLDRYFAILKPLKRSYNRGR---IMLACAW 160
            |.:||.|::.:|.|:|....::|.||||:||:|.:.:||:.|:..|:| |.|..|   ..|..|:
Mosquito   244 WYYTVDWVAGNLFCKLFKLCQMFSLYLSTYVLVLVGVDRWVAVKYPMK-SLNTARRCHRFLFVAY 307

  Fly   161 LGSVVCSIPQAFLFHLEEHPAVTGYFQCVIFNSFRSDFDEKLYQAASMCSMYAFPLIMFIYCYGA 225
            |.|.:.|.||..:|.:.:.|.|..::|||....:...:.|:||...::..|:..||::.|..|.:
Mosquito   308 LLSFLLSTPQWMIFRVAKGPFVEDFYQCVTHGFYTDRWQEQLYTTFTLVFMFIIPLLILIGTYLS 372

  Fly   226 IYLEIYRKSQRVLK-DVIA-ER---FRRSNDD---VLSRAKKRTLKMTITIVIVFIICWTPYYTI 282
            .::.| ..|:::.: |..| :|   :|||:.:   ::.:||.::|::::.||:.|::||||||.:
Mosquito   373 TFMTI-SSSEKIFRIDTSAVDRTTYYRRSDTNRQRLIHKAKMKSLRISVVIVVAFVVCWTPYYIM 436

  Fly   283 SMWYWLDKHSAGKINPL------LRKALFIFASTNSCMNPLVYGLYN---IRGRMNNNNPSVN-- 336
            .:.:..       :||.      |:..:|.|..:||.:|||:||.::   ||.|.|..|..|.
Mosquito   437 MLIFMF-------LNPTERFGEDLQSGIFFFGMSNSLINPLIYGAFHLVPIRQRRNQYNQHVREG 494

  Fly   337 ----------NRHTSLSNRLD------SSNQLMQKQLTNNSLLNGRGQVMAAAVSATTKLANVVS 385
                      |.|......|:      :|:..:.::::..||        ...:.:..:..|.:.
Mosquito   495 SVYFQRSSTFNHHNGHQRNLNPHIKFSNSHSNLPEEISLMSL--------EKDLRSLDENVNQIH 551

  Fly   386 LKGTANGNGSAAAAG 400
            .||...|.|.....|
Mosquito   552 QKGGGGGGGGGGGGG 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AkhR	NP_995639.1	7tmA_AKHR	39..328	CDD:320504	96/313 (31%)
		TM helix 1	40..66	CDD:320504	6/26 (23%)
		TM helix 2	74..101	CDD:320504	10/26 (38%)
		TM helix 3	112..142	CDD:320504	13/29 (45%)
		TM helix 4	151..172	CDD:320504	8/23 (35%)
		TM helix 5	200..229	CDD:320504	8/28 (29%)
		TM helix 6	256..286	CDD:320504	12/29 (41%)
		TM helix 7	298..323	CDD:320504	11/30 (37%)
LOC1281610	XP_061505639.1	None