DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AkhR and gnrhr1

DIOPT Version :9

Sequence 1:	NP_995639.1	Gene:	AkhR / 33942	FlyBaseID:	FBgn0025595	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_001138452.1	Gene:	gnrhr1 / 100270672	ZFINID:	ZDB-GENE-090128-2	Length:	377	Species:	Danio rerio

Alignment Length:	318	Identity:	109/318 - (34%)
Similarity:	178/318 - (55%)	Gaps:	19/318 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 FNDGHRLSITVYSILFVISTIGNSTVLYLLTK---RRLRGPLRIDIMLMHLAIADLMVTLLLMPM 95
            |....|..:....:|||.:.:.|.:||..:|:   |.|...||  :::..||.|||::|.::||:
Zfish    34 FTTAARYRVVATLVLFVFAAVSNLSVLISVTRGRGRHLASHLR--LLIASLASADLVMTFVVMPL 96

  Fly    96 EIVWAWTVQWLSTDLMCRLMSFFRVFGLYLSSYVMVCISLDRYFAILKPLKR--SYNRGRIMLAC 158
            :.:|..||||.:.|.||:|:.|.::|.::.:::::|.:||||:.|||.||:.  :..|.|.:|..
Zfish    97 DAIWNITVQWYAGDAMCKLLCFLKLFAMHSAAFILVVVSLDRHHAILHPLEALDAGRRNRRVLLA 161

  Fly   159 AWLGSVVCSIPQAFLFHLEEHPAVTGYFQCVIFNSFRSDFDEKLYQAASMCSMYAFPLIMFIYCY 223
            ||:.||:.:.||.|::...:...| .:.||....|||..:.|..|......::|.|||::..:||
Zfish   162 AWILSVLLASPQLFIYRALKAEGV-DFVQCATHGSFRHRWQETAYNMFHFVTLYVFPLLVMSFCY 225

  Fly   224 GAIYLEIYRKSQRVLKDVIAERFRRSNDDVLSRAKKRTLKMTITIVIVFIICWTPYYTISMWYWL 288
            ..|.:||.|:..|..........|||..|::.:|:.:||||||.||..|::||||||.:.:|||.
Zfish   226 TRILVEINRQMPRGKGKGGEPCLRRSGADMIPKARMKTLKMTIIIVASFVVCWTPYYLLGIWYWF 290

  Fly   289 DKHSAGKINPL-LRKALFIFASTNSCMNPLVYGLYNIRGRMNNNNPSVNNRHTSLSNR 345
            ..... ::.|: ...|||:|.:.|:|.:|::||.:         .||.....||..:|
Zfish   291 QPRML-QVTPVYAHHALFVFGNLNTCCDPVIYGFF---------TPSFRADITSCFSR 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AkhR	NP_995639.1	7tm_1	55..319	CDD:278431	97/269 (36%)
gnrhr1	NP_001138452.1	7tm_1	56..321	CDD:278431	97/268 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589184
Domainoid	1	1.000	193	1.000	Domainoid score	I3141
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H80348
Inparanoid	1	1.050	208	1.000	Inparanoid score	I3664
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D368588at33208
OrthoFinder	1	1.000	-	-		FOG0003145
OrthoInspector	1	1.000	-	-		otm25742
orthoMCL	1	0.900	-	-		OOG6_105158
Panther	1	1.100	-	-	O	PTHR24241
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X690
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.900