DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Tsp and ism2b

DIOPT Version :9

Sequence 1:NP_001137802.1 Gene:Tsp / 33941 FlyBaseID:FBgn0031850 Length:1060 Species:Drosophila melanogaster
Sequence 2:NP_001018345.1 Gene:ism2b / 553163 ZFINID:ZDB-GENE-050523-4 Length:437 Species:Danio rerio


Alignment Length:314 Identity:69/314 - (21%)
Similarity:102/314 - (32%) Gaps:110/314 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   586 NCPKLPNS--GQEDADLDGHGDGCDD---DADGDNVQNSQDNCWLAYNTEQLDSDGDKVGDVCDN 645
            |.|.|.|:  |.::.::....:..||   |.:.|.|: ...|.|   :|....|..:.:|.....
Zfish    85 NLPDLANADIGSQNPNIQVTIEVLDDPPMDVEMDLVK-EWSNDW---STSSPSSTVEWLGGKKLF 145

  Fly   646 CVLKYNPRQLDTDEDGLG---DECDGDIDNDS---IPNALDNCPLLPNPSQSDVD---------- 694
            ..|.:.....|:.|||.|   ||.| |.|.||   ||:.|         .::|.|          
Zfish   146 WPLFWGYTDADSGEDGTGQAEDEED-DYDYDSGEPIPSGL---------GKTDGDWTHNRYEEKE 200

  Fly   695 --------------------NDGVGDAC-----DNCPNLPNPDQKDRDMDFVGDACHRDID---- 730
                                :...||.|     .:|..:|.||    |.:.||.....:::    
Zfish   201 EEWSTWSPCSVTCGHGNQTRSRSCGDFCTSTESQSCDLVPCPD----DWNSVGHVFPFEMENGTE 261

  Fly   731 --GDDDG-------------------VPNSLDNCPM-----VSNS--DQLDTDGDGTGDECDDDM 767
              |.|.|                   |...|.|||.     |||:  ..||...:.:....|...
Zfish   262 PYGTDVGSCEKWLNCKSEFLQRYLQQVFTELPNCPCSYPSHVSNNIVSLLDVGHERSFQWRDASG 326

  Fly   768 DGDGIPNYKDNCPLAKNPKQDDFNRNG----KGDSCEDDEDV-------DGVPN 810
            ..:.:..||   |.|::..:...::||    ....|.||...       .|.||
Zfish   327 PKERLDIYK---PSARSCLRSGLSKNGTTLAAQHCCYDDNKQLITRGKGAGTPN 377

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TspNP_001137802.1 EGF_CA 477..513 CDD:284955
TSP3 repeat_1C 563..595 CDD:275367 4/10 (40%)
TSP3 repeat_short 632..654 CDD:275365 3/21 (14%)
TSP_3 656..690 CDD:280556 15/39 (38%)
TSP3 repeat_long 656..690 CDD:275366 15/39 (38%)
TSP3 repeat_short 691..713 CDD:275366 8/56 (14%)
TSP3 repeat_long 714..751 CDD:275365 14/68 (21%)
TSP_3 715..751 CDD:280556 14/67 (21%)
TSP3 repeat_short 752..787 CDD:275366 7/34 (21%)
TSP_3 789..822 CDD:280556 8/33 (24%)
TSP_C 841..1038 CDD:283408
coiled coil 245..286 CDD:293927
TSPcc_insect 245..286 CDD:293927
EGF_CA 343..377 CDD:214542
EGF_CA 421..457 CDD:238011
ism2bNP_001018345.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 156..191 16/44 (36%)
TSP1 202..242 CDD:214559 5/39 (13%)
AMOP 266..428 CDD:281737 25/115 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170592960
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.930

Return to query results.
Submit another query.