DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tsp and F14H12.3

DIOPT Version :10

Sequence 1:NP_523495.2 Gene:Tsp / 33941 FlyBaseID:FBgn0031850 Length:1060 Species:Drosophila melanogaster
Sequence 2:NP_508745.1 Gene:F14H12.3 / 180709 WormBaseID:WBGene00017471 Length:257 Species:Caenorhabditis elegans


Alignment Length:272 Identity:59/272 - (21%)
Similarity:75/272 - (27%) Gaps:106/272 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly   347 MC-YPGVQCHDTVNGAQCDSCPAGYEGDGRTCSLRNPCLDTPCPSG----AQC-LQVGYPPYFHC 405
            :| :.|...:....|.|.:  |:|       |   |.|.|:|..||    :.| ...|.|.....
 Worm     8 LCLFQGTLSYVIGGGVQAN--PSG-------C---NVCGDSPQWSGWTEWSSCSAAFGTPVQTRT 60

  Fly   406 ISCPMGHEVNGTSCRDMNECLLYDP---------------CDELATCTNLSPGFQCSPCPVGFDG 455
            ..||.|: ..|.|..:...|:||||               |.  |||..               |
 Worm    61 RLCPSGN-CQGGSTTESKPCVLYDPQPTQPQWGAWGGWSSCS--ATCGG---------------G 107

  Fly   456 THAHGYFADYYSVDYRRQTCLDVDECRTGFFRCPEHSTCINEIGSYRCQC----HEGYVTNGTYS 516
            |..            |.:.|.:                     |...|||    .|....|....
 Worm   108 TMT------------RSRVCNN---------------------GCSTCQCVGAAAESQACNAQPC 139

  Fly   517 C--LDRSSVFMCPDGTVCDRNAVCLRMDNIRHKCHCNVGWAGNGLICGRDTDVDGWPDQAIGCPE 579
            |  ...||...|  ...|.......|    ..:|.|..|..|..:      :.:..|.|| .|| 
 Worm   140 CTWTAWSSWSAC--SVTCGSGGSITR----SRQCSCGSGCTGGSV------EQEPCPQQA-ACP- 190

  Fly   580 LRCQRDNCPKLP 591
              |...|.|..|
 Worm   191 --CTTCNQPPPP 200

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TspNP_523495.2 coiled coil 245..286 CDD:293927
TSPcc_insect 245..286 CDD:293927
EGF_CA 421..457 CDD:238011 10/50 (20%)
EGF_CA 477..508 CDD:429571 4/34 (12%)
TSP3 repeat_1C 563..595 CDD:275367 9/29 (31%)
TSP3 repeat_short 632..654 CDD:275365
TSP_3 656..690 CDD:367074
TSP3 repeat_long 656..690 CDD:275366
TSP3 repeat_short 691..713 CDD:275366
TSP_3 714..751 CDD:367074
TSP3 repeat_long 714..751 CDD:275365
TSP3 repeat_short 752..787 CDD:275366
TSP_3 789..822 CDD:367074
TSP_C 841..1037 CDD:461725
F14H12.3NP_508745.1 TSP1 <39..86 CDD:472794 15/47 (32%)
TSP1 91..139 CDD:214559 14/97 (14%)
TSP1 142..187 CDD:214559 10/56 (18%)
Blue background indicates that the domain is not in the aligned region.

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