DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tsp and LOC100535166

DIOPT Version :9

Sequence 1:	NP_001137802.1	Gene:	Tsp / 33941	FlyBaseID:	FBgn0031850	Length:	1060	Species:	Drosophila melanogaster
Sequence 2:	XP_003200334.3	Gene:	LOC100535166 / 100535166	-ID:	-	Length:	387	Species:	Danio rerio

Alignment Length:	335	Identity:	59/335 - (17%)
Similarity:	111/335 - (33%)	Gaps:	125/335 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 TLDI---SANGATESRNFEIPNINETSTI----RSLALQFSKNRITLHVDCKASTHHDIDMNLAK 144
            |||:   ||.|.      ::.::.:....    |::.|...::|..::|.|:.....::|:.:.:
Zfish   126 TLDLVFWSAGGQ------QVVSVEDVELADGHWRNITLFVQEDRAQVYVGCEEINTQELDLPIQQ 184

  Fly   145 LYTQMDDPV--IKLFRERKYPLHFDGDMEH-----------SLQRANCQKGN----------HRR 186
            :..|.:..:  :::.:.......|.|.:::           .|:...||..:          |..
Zfish   185 ILDQQNAEISGLRIAKGAAKSDRFMGVLQNVRFVFGTTVDAILRNKGCQSSSFIPDVLTLEKHVN 249

  Fly   187 GNRRMLRNKITEREKNKKRDVRGWYEPTIAREGVVDHRHQEVPTDVERGDIPVLNGDCED--ALA 249
            |:...:|...|..:....:||.|:                                .|:|  ::.
Zfish   250 GSSPAIRTHYTGHKTKDLQDVCGF--------------------------------SCDDLTSMF 282

  Fly   250 RSLSDLLALVKLLREDVAHQRQEIAYLRMLLENCAGCKNPLTTDNQLRIEPDCRSANPCYPGVEC 314
            :.|..|..:||.|..|:   ||                  :|.||.|     .::....:.|| |
Zfish   283 KELKGLGVVVKQLSNDL---RQ------------------VTADNNL-----IKTQIKVHEGV-C 320

  Fly   315 L---------DSAAGPRCGHCPLGFIGDGKSCKPGVTCAHHMCYPGVQC-HDTVNGAQCDSCP-- 367
            |         |......|.||         :|:...|....:..|.:.| :.||...:|  ||
Zfish   321 LHNRIVYQDRDEWTVDSCTHC---------TCQNSATVCREISCPLMPCANATVPEGEC--CPRC 374

  Fly   368 -----AGYEG 372
                 ||.:|
Zfish   375 GTPSDAGIDG 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tsp	NP_001137802.1	EGF_CA	477..513	CDD:284955
		TSP3 repeat_1C	563..595	CDD:275367
		TSP3 repeat_short	632..654	CDD:275365
		TSP_3	656..690	CDD:280556
		TSP3 repeat_long	656..690	CDD:275366
		TSP3 repeat_short	691..713	CDD:275366
		TSP3 repeat_long	714..751	CDD:275365
		TSP_3	715..751	CDD:280556
		TSP3 repeat_short	752..787	CDD:275366
		TSP_3	789..822	CDD:280556
		TSP_C	841..1038	CDD:283408
		coiled coil	245..286	CDD:293927	9/42 (21%)
		TSPcc_insect	245..286	CDD:293927	9/42 (21%)
		EGF_CA	343..377	CDD:214542	10/38 (26%)
		EGF_CA	421..457	CDD:238011
LOC100535166	XP_003200334.3	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D120983at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010