Protein Alignment Nhe3 and NHX8

DIOPT Version :10

• Sequence 1: NP_723202.2
• Gene: Nhe3 / 33939
• FlyBaseID: FBgn0028703
• Length: 711
• Species: Drosophila melanogaster
• Sequence 2: NP_172918.2
• Gene: NHX8 / 838028
• AraportID: AT1G14660
• Length: 756
• Species: Arabidopsis thaliana
• Alignment Length: 585
• Identity: 133/585 - (22%)
• Similarity: 231/585 - (39%)
• Gaps: 133/585 - (22%)

  Fly    77 IVGAIIRYAGTSATLVHMQVEPQGVPTYSDKLPPDTLWF-----------RYPVNQTNGTKPPEG 130
            |:||.:.|......:.......:     :|..|.|.:.|           ||   ..|||:.|..
plant     4 IIGAALPYKSPEKAIASSSYSAE-----NDSSPVDAVIFAGTSLVLGTACRY---LFNGTRVPYT 60

  Fly   131 IKTYAY-VFRGQV-----HDVDE--NEIDLKATFDPEVFFNIILPPIIFYAGYSLKKKYFFRNLG 187
            :..... :|.|.:     |::.:  :.|.:....:|::...:.||.::|.:.:|:......|.:|
plant    61 VVLLVIGIFLGSLEYGTKHNLGKLGHGIRIWNGINPDLLLAVFLPVLLFESSFSMDVHQIKRCMG 125

  Fly   188 AILTFAIVGTTLSAFLIGGFMYGCVKLMPKYLSSSFTFLDSLYFGALISPTDPLTILAIFNDLRV 252
            .::..|..|..:|.|.:|..    :||...|   ::.:..||..|.|:..|||:.::|:..:|..
plant   126 QMVLLAGPGVLISTFCLGAL----IKLTFPY---NWDWKTSLLLGGLLGATDPVAVVALLKELGA 183

  Fly   253 DVNLYALVLGESVLNDAVAIVLSGAIQNYGEHYSNTGEFETTAFLRSL----SDFFSI--FLL-- 309
            ...:..|:.|||::||.|::|:                |:  .|.:.:    ||:.||  ||:
plant   184 SKKMTTLIDGESLMNDGVSVVV----------------FQ--LFFKMVMGHNSDWGSIIKFLVQN 230

  Fly   310 ---SLMIGAAMGCLTALMTKFTRVRDFPLLESALFVLMSYSTFLLAEATE---LTGVVAVLFCGI 368
               ::.||.|.|..:....||.    |....:.:.|.:|.|.|....|.|   ::|::.|:..|:
plant   231 SFGAVGIGLAFGIASVFWLKFI----FNDTVAQITVTLSASYFAYYTAQEWAGVSGILTVMILGM 291

  Fly   369 CQAHYTYNNLSEDSRQRTKQIFELLNFLAENFIFSYIGV-------SMFTFPKHHFDAGFIITAF 426
            ..|.:.......||.|.....:|:..::|...:|...||       |..|.........|:...:
plant   292 FFAAFARTAFKGDSHQSLHHFWEMAAYIANTLVFMLSGVIIAESVLSGQTISYKGNSWSFLFLLY 356

  Fly   427 ICAAIGRAVNV-----------YPLSWLLNIKRKPKISTNFQHMLFFAGLRGAMSFALAIR---- 476
            :...:.|.|.|           |.|.|..:|            :|.::|||||:|.:||:.
plant   357 LYVQLSRCVVVGVLYPLLCRSGYGLDWKESI------------ILTWSGLRGAVSLSLALSVKQS 409

  Fly   477 --NTV--SDERQTMLTATSLIVIFTVVIQGGAANFLLNWLKIPVGVDDETEQLNNYQVHSVYNSM 537
              |:.  ||.....|..|..||..|:|:.|.....||:.|:    :|..|........::.:..|
plant   410 SGNSYLSSDTGTRFLFLTGGIVFLTLVVNGSTTQLLLHLLR----MDTLTATKKRILEYTKFEMM 470

  Fly   538 -----------DNSHPQTSD--------GYLQDVEGGGVNRNKMRLSGGTD-TN-LDTPVDGTNG 581
                       |:....::|        ..|:|:||..||.:....:|..| || :|..:...||
plant   471 KTALKAFENLGDDEELGSADWPTVIRHISSLKDLEGRQVNPHDGYEAGSLDPTNIMDIRIRFLNG 535

  Fly   582  581
            plant   536  535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nhe3	NP_723202.2	Na_H_Exchanger	155..>531	CDD:470090	99/415 (24%)
NHX8	NP_172918.2	NhaP	42..>452	CDD:439796	107/457 (23%)