Protein Alignment Nhe3 and NHX1

DIOPT Version :10

• Sequence 1: NP_723202.2
• Gene: Nhe3 / 33939
• FlyBaseID: FBgn0028703
• Length: 711
• Species: Drosophila melanogaster
• Sequence 2: NP_198067.1
• Gene: NHX1 / 832773
• AraportID: AT5G27150
• Length: 538
• Species: Arabidopsis thaliana
• Alignment Length: 617
• Identity: 180/617 - (29%)
• Similarity: 287/617 - (46%)
• Gaps: 138/617 - (22%)

  Fly    25 LDAKATLNH-RIQSLDLLVFVFLLALTVLTIWLFKHHRVSWLHETGLAVIYGLIVGAIIRYAGTS 88
            |.:.:|.:| .:.:|:|  ||.||...::...|.:.:|  |::|:..|::.||         ||.
plant     9 LPSLSTSDHASVVALNL--FVALLCACIVLGHLLEENR--WMNESITALLIGL---------GTG 60

  Fly    89 ATLVHMQVEPQGVPTYSDKLPPDTLWFRYPVNQTNGTKPPEGIKTYAYVFRGQVHDVDENEIDLK 153
            .|::.:.                                 :|..::..|
plant    61 VTILLIS---------------------------------KGKSSHLLV---------------- 76

  Fly   154 ATFDPEVFFNIILPPIIFYAGYSLKKKYFFRNLGAILTFAIVGTTLSAFLIGGFMYGCVKLMPKY 218
              |..::||..:||||||.||:.:|||.||||...|:.|..|||.:|..:|.   .|..:...|.
plant    77 --FSEDLFFIYLLPPIIFNAGFQVKKKQFFRNFVTIMLFGAVGTIISCTIIS---LGVTQFFKKL 136

  Fly   219 LSSSFTFLDSLYFGALISPTDPLTILAIFNDLRVDVNLYALVLGESVLNDAVAIVLSGAIQNYG- 282
            ...:|...|.|..||:.:.||.:..|.:.|.....: ||:||.||.|:|||.::|:..|||::.
plant   137 DIGTFDLGDYLAIGAIFAATDSVCTLQVLNQDETPL-LYSLVFGEGVVNDATSVVVFNAIQSFDL 200

  Fly   283 EHYSNTGEFETTAFLRSLSDFFSIFLLSLMIGAAMGCLTA-LMTKFTRVRDFPLLESALFVLMSY 346
            .|.::...|..      |.:|..:||||.::|||.|.::| ::.|....|.....|.||.:||:|
plant   201 THLNHEAAFHL------LGNFLYLFLLSTLLGAATGLISAYVIKKLYFGRHSTDREVALMMLMAY 259

  Fly   347 STFLLAEATELTGVVAVLFCGICQAHYTYNNLSEDSRQRTKQIFELLNFLAENFIFSYIGV---- 407
            .:::|||..:|:|::.|.||||..:|||::|::|.||..||..|..|:||||.|||.|:|:
plant   260 LSYMLAELFDLSGILTVFFCGIVMSHYTWHNVTESSRITTKHTFATLSFLAETFIFLYVGMDALD 324

  Fly   408 -----SMFTFPKHHFDAGFIITAFICAAIGRAVNVYPLSWLLNIKRK---PKISTNFQHMLFFAG 464
                 |:...|........|:...:  .:|||..|:|||:|.|:.:|   .||:.|.|.:::::|
plant   325 IDKWRSVSDTPGTSIAVSSILMGLV--MVGRAAFVFPLSFLSNLAKKNQSEKINFNMQVVIWWSG 387

  Fly   465 L-RGAMSFALA----IRNTVSDER--QTMLTATSLIVIFTVVIQGGAANFLLNWLKIPVGVDDET 522
            | |||:|.|||    .|...:|.|  ..|:|:|..:.:|:.|:.|.....|:::| :|
plant   388 LMRGAVSMALAYNKFTRAGHTDVRGNAIMITSTITVCLFSTVVFGMLTKPLISYL-LP------- 444

  Fly   523 EQLNNYQVHSVYNSMDNSHPQTSDGYLQD----VEGGGVNRNKMRLSGGTDTNLDTPVDGTNGSL 583
                 :|..:.....|::.|::....|.|    :|..| |.|..|            .|...|.|
plant   445 -----HQNATTSMLSDDNTPKSIHIPLLDQDSFIEPSG-NHNVPR------------PDSIRGFL 491

  Fly   584 GGASGGRRRNSHEKAILARIWGNFDTKYMKPL 615
            ...:    |..|      ..|..||..:|:|:
plant   492 TRPT----RTVH------YYWRQFDDSFMRPV 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nhe3	NP_723202.2	Na_H_Exchanger	155..>531	CDD:470090	140/396 (35%)
NHX1	NP_198067.1	Na_H_Exchanger	44..>468	CDD:470090	154/510 (30%)